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A-type K+ channel

K+-Channel Transgenes Reduce K+ Currents in Paramecium, Probably by a Post-translational Mechanism

K+-Channel Transgenes Reduce K+ Currents in Paramecium, Probably by a Post-translational Mechanism

... PAK11 is 1 of more than 15 members in a gene family that encodes K ⫹ -channel pore-forming subunits in Paramecium tetraurelia. Microinjection of PAK11 DNA into macronuclei of wild-type cells results ...

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A Mathematical Model of a Midbrain Dopamine Neuron Identifies Two Slow Variables Likely Responsible for Bursts Evoked by SK Channel Antagonists and Terminated by Depolarization Block

A Mathematical Model of a Midbrain Dopamine Neuron Identifies Two Slow Variables Likely Responsible for Bursts Evoked by SK Channel Antagonists and Terminated by Depolarization Block

... novel type of bursting that we call “inverted square wave bursting” when exposed to Ca 2 + -activated small conductance (SK) K + channel blockers in ...This type of bursting has three phases: ...

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An inwardly rectifying K+ channel is required for patterning

An inwardly rectifying K+ channel is required for patterning

... Mutations that disrupt function of the human inwardly rectifying potassium channel KIR2.1 are associated with the craniofacial and digital defects of Andersen-Tawil Syndrome, but the contribution of Kir channels ...

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The molecular mechanisms and pharmacotherapy of ATP-sensitive potassium channel gene mutations underlying neonatal diabetes

The molecular mechanisms and pharmacotherapy of ATP-sensitive potassium channel gene mutations underlying neonatal diabetes

... the channel contain- ing all wild-type subunits, so the resulting ATP sensitivity of heterozygous population is very close, but not identical, to that of a pure wild-type channel ...

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COMPARATIVE ANALYSIS AND IDENTIFICATION OF GENES RELATED TO POTASSIUM TRANSPORTER FAMILIES IN SORGHUM BICOLOR

COMPARATIVE ANALYSIS AND IDENTIFICATION OF GENES RELATED TO POTASSIUM TRANSPORTER FAMILIES IN SORGHUM BICOLOR

... with K+ transport in Sorghum ...ORK Type), eight genes to CNGC (Table 2), 4 genes to Trk family (Table 3) and two putative K+ /H+ antiporter genes were analyzed (Table ...sorghum K+ ...

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Transcriptional control of Ca(2+) activated K(+) channel expression: identification of a second, evolutionarily conserved, neuronal promoter

Transcriptional control of Ca(2+) activated K(+) channel expression: identification of a second, evolutionarily conserved, neuronal promoter

... different channel densities. The control of channel density can be just as important as channel type in determining a cell’s electrical properties (Baro et ...

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Characteristics of Five Types of K+ Channel in Cultured Locust Muscle

Characteristics of Five Types of K+ Channel in Cultured Locust Muscle

... Only outward currents were observed for the type 1 channel in excised, outside-out patches, to give a chord conductance of 5 pS between pipette potentials of OmV and +120mV.. In inside-o[r] ...

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Muscle channelopathies and critical points 
in functional and genetic studies

Muscle channelopathies and critical points in functional and genetic studies

... ion channel genes, by antibodies directed against ion channel proteins, or by changes of cell homeostasis leading to aberrant splicing of ion channel RNA or to disturbances of modification and ...

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Cracking the Secret Code of the Selectivity Ratio between K and Na Ions in the KcsA K channel

Cracking the Secret Code of the Selectivity Ratio between K and Na Ions in the KcsA K channel

... between K + and Na + ions in the KcsA channel ...of K + ...the channel. Figure 1 shows how K + ions enter the K + channel and its ...

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A Generalizable Semantics for an Inheritance Reasoner

A Generalizable Semantics for an Inheritance Reasoner

... Channel theory provides a formal framework which admits distinctions of fine granularity attuned to the needs of providing semantics to the family of inheritance reasoners under consideration. The sanctioning of a ...

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I. Ion Channels in Human THP-1 Monocytes

I. Ion Channels in Human THP-1 Monocytes

... Figure 5B and C illustrate I SK currents during volt- age pulses. In general, there was no obvious or consis- tent time dependence. In the cell illustrated, there was a suggestion of turn-on during pulses to positive ...

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Monte Carlo simulation of electrolyte solutions in biology: in and out of equilibrium

Monte Carlo simulation of electrolyte solutions in biology: in and out of equilibrium

... We have to make a clear distinction between models and methods [1] even if these two concepts often overlap and are confused (especially, in the case of detailed all-atom models integrated in simulation pack- ages). Let ...

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Computer modelling and experimental investigation of building integrated sub wet bulb temperature evaporative cooling system

Computer modelling and experimental investigation of building integrated sub wet bulb temperature evaporative cooling system

... dry channel while water sips through the micro-pores of the panels on the back surface to wet its surface and form the wet ...dry channel through the wet channel as shown by the arrangement of ...wet ...

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A Comparative Study of Coolants Based on the Cooling Time of Injection Molding

A Comparative Study of Coolants Based on the Cooling Time of Injection Molding

... Cooling channel of Ø6 mm is used with the channel distance of 15 mm above and below the components. Figure 5 explain the placement of the cooling channels with respect to component. The cooling channels ...

5

Zeolite as natural gas adsorbents

Zeolite as natural gas adsorbents

... zig-zag channel, however once the channel is blocked, the adsorbate could not diffuse further to the adsorption ...323 K and 137 kPa, cage structures shows better adsorptive characteristic than the ...

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K+ transport in Malpighian tubules of Tenebrio
molitor L : a study of electrochemical gradients and basal K+
uptake mechanisms

K+ transport in Malpighian tubules of Tenebrio molitor L : a study of electrochemical gradients and basal K+ uptake mechanisms

... The mechanisms underlying ion transport in insect Malpighian tubules have been studied extensively in a number of species (for reviews, see Maddrell and O’Donnell, 1992; Nicolson, 1993; Pannabecker, 1995; Beyenbach, ...

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Inhibition of T Cell and Stimulation of B Cell Proliferation by Restraint Stress Mediated by Voltage Gated Potassium Channel 1 3 Expression

Inhibition of T Cell and Stimulation of B Cell Proliferation by Restraint Stress Mediated by Voltage Gated Potassium Channel 1 3 Expression

... In addition, T cells including Th1, Th2, Th17, natural killer T cells, and regulatory T cells (Tregs), may con- tribute to the development and/or progression of diseases. An imbalance between different T cells may lead ...

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CO2 dependent opening of an inwardly rectifying K+ channel

CO2 dependent opening of an inwardly rectifying K+ channel

... open probability of the channel was estimated from all- points histograms. The area under the curve corresponding to single-channel or multiple-channel openings was obtained from a sum of up to four ...

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Review: Evolutionary link between prokaryotic and eukaryotic K+ channels

Review: Evolutionary link between prokaryotic and eukaryotic K+ channels

... domains of life. Hence, we have constructed a phylogenetic tree from the majority of known sequences by means of the CLUSTREE algorithm using a variable-sequence window (Fig. 3). By selecting a region (e.g. of 101 amino ...

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Characterization of single non inactivating potassium channels in primary neuronal cultures of Drosophila

Characterization of single non inactivating potassium channels in primary neuronal cultures of Drosophila

... Permeability and gating properties of single, non-inactivating K + channel currents in neurons of eag, a mutant which has defects in the delayed rectifier K + channel, were indistinguish[r] ...

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