Aberrant Methylation
Lack of Aberrant Methylation in an Adjacent Area of Left Sided Colorectal Cancer
... higher methylation in ADJ than in ...However, methylation levels of most DMGs in cancer did not differ between ADJ and LNM, indicating that promoter hypermethylation in distant cancer adjacent areas, a ...
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Aberrant Methylation-Mediated Suppression of APAF1 in Myelodysplastic Syndrome
... The aberrant methylation of genes involved in the apoptotic pathway is poorly defined in ...When aberrant methylation occurs in the promoter of genes that suppress tumorigenesis, it can lead ...
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Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma
... DAPK1 methylation in DLBCL biopsies, a much smaller proportion of the pa- tients have aberrant methylation in cfDNA from plasma, possibly because only the more advanced tumors shed DNA into the ...
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Original Article ART1 induces aberrant methylation
... DNA methylation occur in cancer, including hypomethylation of oncogenes and hyper- methylation of tumor suppressor genes ...of aberrant methylation sta- ...hypo- methylation activates ...
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A Study on the Aberrant Methylation of Colorectal Cancer MLH1 Gene
... island aberrant methylation on the regulation of MLH1 gene ...the methylation status of the first exon of MLH1 gene in the ...the methylation level of cancer tissues was statistically ...
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Genome-wide analysis of aberrant methylation of enhancer DNA in human osteoarthritis
... enhancer methylation pattern, we used SMART to identify the differentially methylated CpG sites (DMCs) across three groups from all available CpGs in the human ...more methylation than other genomic ...the ...
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Aberrant Methylation of APAF-1 Gene in Acute Myeloid Leukemia Patients
... DNA methylation and interestingly observed that the methylation pattern of approximately 580 recessive genes was significantly different between the female and male subjects 17 ...the methylation ...
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Association between HIC1 and RASSF1A Promoter Hypermethylation with MTHFD1 G1958A Polymorphism and Clinicopathological Features of Breast Cancer in Iranian Patients
... DNA methylation levels in normal and tumor tissues could therefore influence the susceptibility to this tumor ...of aberrant methylation of HIC1 and RASSF1A gene promoters and their association with ...
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Original Article Quantitative DNA hypomethylation of PTEN in Uyghur patients with type 2 diabetes mellitus
... evaluate methylation patterns at multiple CpG sites with- in the promoter region of PTEN in ...significant aberrant methylation of PTEN between IFG/IGTs and NGTs, we found that aberrant ...
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Gomih_unc_0153D_17332.pdf
... Differential methylation of DMRs associated with PEG3, PEG1/MEST and IGF2 expression was strongly associated with HPV infection among women with ICC [93, ...by aberrant methylation and subsequent ...
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Methylation and Expression Status of SOCS1 and SOCS3 in Oral Lichen Planus
... by aberrant methylation in the promoter region of the SOCS 3 gene is associated with several types of malignancy, such as hepatocellular carcinoma, multiple myeloma, malignant melanoma, and colorectal ...
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Analysis of the transcriptional regulation of cancer-related genes by aberrant DNA methylation of the cis-regulation sites in the promoter region during hepatocyte carcinogenesis caused by arsenic
... arsenic methylation metabolism and may be the potential target of arsenic-induced ...have aberrant DNA methylation have been ...to aberrant methylation sites cannot well reflect the ...
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Original Article Aberrant promoter methylation of SH3GL2 gene in vulvar squamous cell carcinoma correlates with clinicopathological characteristics and HPV infection status
... that aberrant methylation might be the main reason of SH3GL2 downregulation or absence in ...gene methylation participated in a variety of tumors occurrence and ...moter methylation and ...
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Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities
... lowest methylation levels, resembling peripheral blood leukocytes, and MS2 was ...the methylation clusters, but homozygous deletions of CDKN2A were more frequent in ...the methylation clusters with ...
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CpG island methylation of TMS1/ASC and CASP8 genes in cervical cancer
... by aberrant methylation ...DNA methylation in breast cancer ...that aberrant methylation of the 5' region of TMS1/ASC is well correlated with loss of expression in ovarian ...for ...
5
Aberrant Vimentin Methylation Is Characteristic of Breast Cancer
... that aberrant methylation of the vi- mentin gene is frequently found to be methylated in advanced colorectal carcinomas and is closely related with colorectal ...of methylation on CpG region near the ...
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SHOX2 and WT1 Promoter Methylation Correlates with the Lung Cancer in Iranian Patients
... between aberrant promoter methylation of the two genes: SHOX2(Short stature homeobox 2) and WT1(Wilms’ tumor gene1), in the plasma samples of the Iranian lung cancer ...DNA methylation kit and ...
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Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension
... The idea that cardiac and metabolic disease can have intrauterine origins, referred to as developmental ori- gins of health and disease (DOHaD), was initially based on early epidemiological studies of prenatal nutri- ...
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Gene Expression and Promoter Methylation Status of VHL, Runx-3, E-cadherin, P15 and P16 Genes During EPO-Mediated Erythroid Differentiation of CD34+ Hematopoietic Stem Cells
... So methylation pattern of CpG islands was an impressive tool to understanding both normal and aberrant gene expression, in this context current study try to find out the alternation of methylation ...
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Zhang_unc_0153D_15904.pdf
... Earlier relevant efforts focused on analyzing two-dimensional genomic datasets. For example, eQTL method can jointly analyze SNP and gene expression data to identify target genes of regulatory SNPs [Zhang, et al. 2010]. ...
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