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activated prothrombin complex concentrate

Activated prothrombin complex concentrate to reverse the factor Xa inhibitor (apixaban) effect before emergency surgery: a case series

Activated prothrombin complex concentrate to reverse the factor Xa inhibitor (apixaban) effect before emergency surgery: a case series

... received activated prothrombin complex concentrate to reverse the anticoagulation effect before emergency cardiovascular ...received activated prothrombin complex ...

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Activated prothrombin complex concentrate factor VIII inhibitor bypassing activity (FEIBA) for the reversal of warfarin-induced coagulopathy

Activated prothrombin complex concentrate factor VIII inhibitor bypassing activity (FEIBA) for the reversal of warfarin-induced coagulopathy

... of activated PCC or FEIBA rather than the higher doses of non- activated three-factor PCC preparations available on the American market, such as Profilnine (Grifols) or Bebulin ...

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“Hemophilia and its Treatment: Brief Review” by Nikisha G. N., Menezes G. A., India.

“Hemophilia and its Treatment: Brief Review” by Nikisha G. N., Menezes G. A., India.

... Hemophilia is a genetic bleeding disorder. Hemophilia A or B is treated by recombinant clotting factor VIII or factor IX and immunosuppressives to prevent formation of alloantibodies and inhibitors. Formation of ...

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PREPARATION OF HIGHLY PURIFIED SOLVENTDETERGENT COA GULATION FACTOR VII AND FACTOR IX CONCENTRATES FROM PROTHROMBIN COMPLEX (PPSB)

PREPARATION OF HIGHLY PURIFIED SOLVENTDETERGENT COA GULATION FACTOR VII AND FACTOR IX CONCENTRATES FROM PROTHROMBIN COMPLEX (PPSB)

... and prothrombin complex concentratesl3-16 have been successfully ...an activated prothrombin complex concentrate which has been widely used in the treatment of hemophilia ...

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An Exploratory Cohort Study Comparing Prothrombin Complex Concentrate and Fresh Frozen Plasma for the Treatment of Coagulopathy After Complex Cardiac Surgery

An Exploratory Cohort Study Comparing Prothrombin Complex Concentrate and Fresh Frozen Plasma for the Treatment of Coagulopathy After Complex Cardiac Surgery

... the number of units of red blood cells transfused (median, [IQR] 2 [1-4] vs. 3 [1-5] units, p=0.181). The final propensity score included preoperative INR, postoperative activated partial thromboplastin time, and ...

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Preparation of factor VII concentrate using CNBr-activated

Preparation of factor VII concentrate using CNBr-activated

... eluted prothrombin complex was used as starting material for purifica- tion of coagulation factor ...thrombin complex (50 ml) was treated with a mixture of ...

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Safety and efficacy of prothrombin complex concentrate as first line treatment in bleeding after cardiac surgery

Safety and efficacy of prothrombin complex concentrate as first line treatment in bleeding after cardiac surgery

... the activated clotting time (ACT) was maintained above 450 ...thromboelastography, prothrombin and activated partial thromboplastin times, and platelet ...

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Prothrombin complex concentrate (Beriplex P/N) in severe bleeding: experience in a large tertiary hospital

Prothrombin complex concentrate (Beriplex P/N) in severe bleeding: experience in a large tertiary hospital

... Cryoprecipitate (one dose equivalent to 10 packs) was admin- istered when the fibrinogen level dropped below 1.0 g/l and the patient was bleeding. Clinical judgement was also involved in the decision-making process. Poor ...

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Four-factor prothrombin complex concentrate improves thrombin generation and prothrombin time in patients with bleeding complications related to rivaroxaban: a single-center pilot trial

Four-factor prothrombin complex concentrate improves thrombin generation and prothrombin time in patients with bleeding complications related to rivaroxaban: a single-center pilot trial

... recombinant activated factor seven, activated prothrombin complex concentrates or other coagulation factor concentrates (except fibrinogen con- centrate, DDAVP and tranexamic acid) were not ...

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Endogenous thrombin potential following hemostatic therapy with 4 factor prothrombin complex concentrate: a 7 day observational study of trauma patients

Endogenous thrombin potential following hemostatic therapy with 4 factor prothrombin complex concentrate: a 7 day observational study of trauma patients

... recombinant activated FVII (rFVIIa), has been re- ported to increase the risk of thromboembolic adverse events among bleeding patients without hemophilia ...

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Goal directed coagulation management of major trauma patients using thromboelastometry (ROTEM®) guided administration of fibrinogen concentrate and prothrombin complex concentrate

Goal directed coagulation management of major trauma patients using thromboelastometry (ROTEM®) guided administration of fibrinogen concentrate and prothrombin complex concentrate

... extrinsically activated thromboelastometric test (EXTEM), a test that uses rabbit brain thromboplastin as an activator, and fibrin-based thromboelastometric test (FibTEM), a test that assesses the fibrin-based ...

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Impact of fibrinogen concentrate alone or with prothrombin complex concentrate (+/− fresh frozen plasma) on plasma fibrinogen level and fibrin-based clot strength (FIBTEM) in major trauma: a retrospective study

Impact of fibrinogen concentrate alone or with prothrombin complex concentrate (+/− fresh frozen plasma) on plasma fibrinogen level and fibrin-based clot strength (FIBTEM) in major trauma: a retrospective study

... Blood samples were drawn as soon as possible following ER admission, either from arterial lines or, in less severe cases, from venous lines. For coagulation monitoring, citrated blood was collected in two standard ...

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Comparison of 3-Factor Prothrombin Complex Concentrate and Low-Dose Recombinant Factor VIIa for Warfarin Reversal

Comparison of 3-Factor Prothrombin Complex Concentrate and Low-Dose Recombinant Factor VIIa for Warfarin Reversal

... dose activated recombinant factor VII provided a more rapid and complete reversal of warfarin anticoagulation as determined by reduction of the INR to a value of ...factor prothrombin complex ...

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Prothrombin complex concentrate in surgical patients: retrospective evaluation of vitamin K antagonist reversal and treatment of severe bleeding

Prothrombin complex concentrate in surgical patients: retrospective evaluation of vitamin K antagonist reversal and treatment of severe bleeding

... Another alternative to FFP for treatment of life-threatening bleeding is activated recombinant factor VII (rFVIIa). This is approved for use as a bypassing agent in hemophiliac patients who have inhibitor ...

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Clinical review: Clinical management of new oral anticoagulants: a structured review with emphasis on the reversal of bleeding complications

Clinical review: Clinical management of new oral anticoagulants: a structured review with emphasis on the reversal of bleeding complications

... aPCC, activated prothrombinase complex concentrate; aPTT, activated partial thromboplastin time; AUC, area under the curve; bid, twice daily; BT, bleeding time; ECT, ecarin clotting time; ETP, ...

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The reversal effect of prothrombin complex concentrate (PCC), activated PCC and recombinant activated factor VII against anticoagulation of Xa inhibitor

The reversal effect of prothrombin complex concentrate (PCC), activated PCC and recombinant activated factor VII against anticoagulation of Xa inhibitor

... Fig. 3 Difference in thrombin generation parameters after adding reversal agents in different doses. Differences in thrombin generation parameters are expressed as per cent difference from baseline (rivaroxaban with no ...

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Role of prothrombin complex concentrate in perioperative coagulation therapy

Role of prothrombin complex concentrate in perioperative coagulation therapy

... cardiocentesis, activated PCC (FEIBA, 26 U/kg) was intravenously given, and “notable slowing of bleeding” was observed by the ...of activated PCC (16 U/kg) was administered for sus- pected bleeding, and no ...

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Efficacy of prothrombin complex concentrates for the emergency reversal of dabigatran induced anticoagulation

Efficacy of prothrombin complex concentrates for the emergency reversal of dabigatran induced anticoagulation

... by activated partial thromboplastin time (aPTT)), and general measures such as volume replacement and blood product ...fibrinogen concentrate, cryoprecipitate, fresh frozen plasma, platelets) may be crit- ...

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Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model

Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model

... shock. Prothrombin complex concentrate (PCC), activated PCC (aPCC) and recombinant activated factor VII (rFVIIa) have been pro- posed as candidates for reversing the anticoagulant ...

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The Bleeding Profile [ PT- APTT- PLATELETS COUNT ] in Apparently Normal Sudanese Pregnant Women during the Second and the Third Trimesters (2016)

The Bleeding Profile [ PT- APTT- PLATELETS COUNT ] in Apparently Normal Sudanese Pregnant Women during the Second and the Third Trimesters (2016)

... Prothrombin time showed significant difference, and appear to be slightly higher in third trimester than second and controls, this result disagrees with study done with Huda ...

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