activation transcription factor 3
Transcription factor activity of estrogen receptor α activation upon nonylphenol or bisphenol A treatment enhances the in vitro proliferation, invasion, and migration of neuroblastoma cells
... To study the specificity of bisphenol A and nonylphenol in regulating ER α activity, breast cancer MDA-MB-231 cells, which lack ER α (Figure 3), were used for ER α over- expression. In the presence of bisphenol A ...
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Activation of the MEF2 transcription factor in skeletal muscles from myotonic mice
... Immunoblotting. Muscle protein was extracted from dissected white vastus muscles by homogenization in lysis buffer (50 mM HEPES, pH 7.6, 250 mM NaCl, 0.1% Nonidet P-40 [NP-40], 5 mM EDTA, 1 mM DTT, and protease inhibitor ...
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Reovirus-Induced Apoptosis Requires Activation of Transcription Factor NF-κB
... Insight into the mechanisms by which reoviruses trigger apoptosis has emerged from studies of viral prototype strains that vary in their capacity to elicit this cellular response. Reo- virus strains type 3 Abney ...
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Effects of Nonstructural Proteins NS1 and NS2 of Human Respiratory Syncytial Virus on Interferon Regulatory Factor 3, NF-κB, and Proinflammatory Cytokines
... regulatory factor 3 (IRF-3) and nuclear factor B (NF- ...suppress activation and nuclear translocation of ...B activation was evaluated in Vero cells, which lack the ...
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Activation of AP-1-Dependent Transcription by a Truncated Translation Initiation Factor
... initiation factor 3 (eIF3) that has also been reported to interact with subunits of the proteasome and the COP9 ...AP-1 transcription factor ...the activation of Pap1 ...
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Anti cancer activity of Ginger (Zingiber officinale) leaf through the expression of activating transcription factor 3 in human colorectal cancer cells
... from transcription activa- tion of ATF3 promoter, ATF3 promoter (-1420/+34) trans- fected HCT116 and SW480 cells were incubated with 25, 50 and 100 μg/ml of GL for 24 ...mRNA activation by GL started to be ...
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Activating transcription factor 3 modulates protein kinase C epsilon activation in diabetic peripheral neuropathy
... the activation of intracellular responses to neuropathic manifestations has not been elucidated; specifically, whether activating transcription factor 3 (ATF3) is responsible for neuronal ...
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Anti Inflammatory properties of Salograviolide A purified from Lebanese plant Centaurea ainetensis
... the activation and translocation of the transcription factor, nuclear fac- tor kappa B (NF-κB) ...NF-κB activation could be beneficial in the treatment of inflammation ...
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The cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter.
... Plasmid RP19 was used as the template for synthesis of p19 antisense tran- scripts used in the RNase protection assay. RP19 was constructed by inserting a SacII/BamHI fragment (AAV nt 814 to 1045) into homologous sites ...
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Activation of Transcription of the Human Cytomegalovirus Early UL4 Promoter by the Ets Transcription Factor Binding Element
... EMSA. DNA fragments used in electrophoretic mobility shift assay (EMSA) were generated by using primer 5⬘-GCAGGTATcTAGaGTATCCG-3⬘ and primer 5⬘-CCTCACgcTagCCCGGACCAGAGCCG-3⬘ (31) for PCR amplifica- tion of ...
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Regulation of the master regulator FOXM1 in cancer
... CCCTC-binding factor (CTCF), cAMP responsive element-binding protein (CREB), sig- nal transducer and activator of transcription 3 (STAT3), and E2F interact directly with their binding sites and up- ...
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Major Human Cytomegalovirus Structural Protein pp65 (ppUL83) Prevents Interferon Response Factor 3 Activation in the Interferon Response
... glycoprotein-mediated activation of this IFN-like response is controlled through NF-B (76–78) and may benefit viral infection, given the distribution of NF-B sites on the viral genome ...gene ...
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Evolution of the activation domain in a Hox transcription factor
... Ubx activation was monitored by the intensity of the blue color generated by the lacZ reporter, benchmarked against a color standard ...an activation domain, yields white ...for transcription ...
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Activation of Latent Transgenes in Arabidopsis Using a Hybrid Transcription Factor
... (Figure 3), and found to have very low amounts, not cated as the target of the potently herbicidal natural significantly different from assay background (Table ...(Figure 3; tion should result in lethality, ...
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Krüppel-like factor 4, a novel transcription factor regulates microglial activation and subsequent neuroinflammation
... of 3 and 6 hours of LPS treatment and this increase was also found to be significant with respect to control (p < ...Microglial activation and neuroin- flammation is also associated with the release of ...
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Temporal Hierarchy of Gene Expression Mediated by Transcription Factor Binding Affinity and Activation Dynamics
... FIG 3 Effects of binding affinities on gene expression of PhoB-regulated ...the transcription start (see Text S1 in the supplemental material for detailed sequences and the positioning of Pho ...and ...
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Binding and Transcriptional Regulation by 14-3-3 (Bmh) Proteins Requires Residues Outside of the Canonical Motif
... of transcription. Yeast 14-3-3 proteins, known as Bmh, inhibit a post-DNA binding step in transcription activation by Adr1, a glucose-regulated transcription factor, by ...
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Herpesvirus Saimiri STP-A Oncoprotein Utilizes Src Family Protein Tyrosine Kinase and Tumor Necrosis Factor Receptor-Associated Factors To Elicit Cellular Signal Transduction
... 7. Activation of ICAM-1 promoter activity and enhanced expression of ICAM-1 protein by ...individual transcription factor binding sites are as follows: the TRE box indicates the TNF- ␣ response ...
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Role of the NFκB-signaling pathway in cancer
... Abnormal activation of signaling pathways is involved in tumor pathogenesis and plays critical roles in growth, progression, and relapse of ...Excessive activation of the NFκB- signaling pathway has been ...
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The Role of Cytokine Interleukin 2, Transcription Factor of FoxP3 in the Immunological Regulation of Allergic Rhinitis
... Immunologic role in AR is about Th1 and Th2 cells balances. Most individuals do not trigger a strong response of Th2 cells to environmental antigens. In atop- ic patients, a strong response to Th2 that produces cytokines ...
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