ACTIVE PHARMACEUTICAL INGREDIENT (API)
Preparation of cocrystal in excipient systems by advanced pharmaceutical methods
... the active pharmaceutical ingredient ...the API to possess a basic or acidic ionisable group. Pharmaceutical cocrystals offer an alternative to salt forms as a means of improving the ...
254
Crystal structure of pirfenidone (5 methyl 1 phenyl 1H pyridin 2 one): an active pharmaceutical ingredient (API)
... an active pharmaceutical ingredient (API) approved in Europe and Japan for the treatment of Idiopathic pulmonary fibrosis (IPF), is reported here for the first ...
7
A NOVEL VALIDATED METHOD FOR DETERMINATION OF GENOTOXIC IMPURITES IN BEPOTASTINE BESILATE (API) WITH RESERVE PHASE HPLC TECHNICS
... Besilate API has Accurate, precision, reproducible, rugged, linear and robust ...of active pharmaceutical ingredient such as content Methyl benzene sulphonate and butyl benzene sulphonate in ...
14
Simultaneous Determination of N Acetyl Cysteine and Taurine by HPTLC Method in Active Pharmaceutical Ingredient and Pharmaceutical Dosage Form
... both active pharmaceutical ingredients (APIs) and marketed tablet ...in active pharmaceutical ingredient and tablet dosage form and to validate as per ICH ...
10
Analytical method for piperazine in an active pharmaceutical ingredient using chemical derivatization and HPLC UV
... A method to form a UV-active derivative of piperazine was developed. The method was based on the reaction of piperazine with NBD-Cl (4-chloro-7-nitrobenzofuran), forming a stable derivative, which was ...
6
Synthesis of fesoterodine: An enantiopure active pharmaceutical ingredient (API)
... Fesoterodine (1) is used to treat overactive bladder (a common problem with old age, a condition in which the bladder muscles contract unconcontrollably and cause frequent urination, urgent need to urinate, and inability ...
21
Isolation of Bulk Amount of Piperine as Active Pharmaceutical Ingredient (API) from Black Pepper and White Pepper (Piper nigrum L )
... Piperine was successfully isolated in a pure crystal form and that isolated crystals were characterized by its melting point which showed within the stan- dard range (129˚C - 130˚C) indicating no impurities and were used ...
10
Simultaneous determination of Ambroxal hydrochloride and Salbutamol Sulphate in pharmaceutical dosage by reverse phase high performance liquid chromatography
... pre-analyzed active pharmaceutical ingredient and reanalyzing the mixture by proposed ...from active pharmaceutical ...material, active pharmaceutical ingredient ...
5
Reversed phase high performance liquid chromatography method for determination of carvedilol hydrochloride from active pharmaceutical dosage form
... pre-analyzed active pharmaceutical ingredient and reanalyzing the mixture by proposed ...from active pharmaceutical ...material, active pharmaceutical ingredient ...
5
Stability indicating RP HPLC PDA method for the estimation of quetiapine fumarate in bulk and pharmaceutical dosage forms
... and pharmaceutical dosage ...bulk active pharmaceutical ingredient was subjected to thermal, photolytic, hydrolytic (acidic and basic) and oxidative stress conditions and stressed samples were ...
8
Modification of physicochemical and micromeritic properties of active pharmaceutical ingredient by crystallization technique
... 2) enzyme. Celecoxib is prescribed mainly in osteoarthritis, rheumatoid arthritis, 100 mg once/twice daily. In certain conditions like familial adenomatous polyopsis The introduction of fold selectivity) in the ...
5
Implementation of basic quality control tests for malaria medicines in Amazon Basin countries: results for the 2005–2010 period
... Level 2 comprises methodologies that can be per- formed in the field. Currently, as implemented by PQM, utilizes basic tests to evaluate four critical medicines quality attributes - identity, content, impurities, and ...
11
Scarce quality assurance documentation in major clinical trial registries for approved medicines used in post marketing clinical trials
... Indeed, a cGMP certificate sustains the quality standards of the manufacturing process and allows identification of substandard medicines. In turn, quality testing provides information on the integrity of the ...
6
SULFONIC ACID COUNTER IONS QUANTIFICATION IN PHARMACEUTICALS BY ION CHROMATOGRAPHY
... in pharmaceutical ingredients (doxazosin mesylate, amlodipine besylate and clopidogrel camphor sulfonate) by suppressed conductivity anion ...in API taken for the ...
8
IDENTIFICATION AND CHARACTERIZATION OF E, Z ISOMERS FOR ACID DEGRADENTS OF SECONDARY ALCOHOL IN API BY HS/GC/ EI MS
... any active pharmaceutical ingredient in sulphate salt form and 2°alcohols as process solvents in Gas Chromatography-Head Space analysis, there is a possibility of degrdation of secondary alcohols and ...
7
Comparison of the determination of a low-concentration active ingredient in pharmaceutical tablets by backscatter and transmission raman spectrometry
... reduced with transmission measurements and a root mean square error of prediction of 1.2% was achieved for the API with a 5 s acquisition time. Hargreaves et al. 31 used transmission Raman measurements to quantify ...
25
QUALITY ASSESSMENT IN THE EXTEMPORANEOUS PEDIATRIC PREPARATION OF POWDER PAPERS CONTAINING CRUSHED TABLETS OF SPIRONOLACTONE OR AMIODARONE
... Powder papers could replace capsules as they contain tablet powder and are an inexpensive, accessible, an easy-to-prepare alternative and lightweight physical state, which facilitates transport and storage. Among the ...
28
Designing the next generation of medicines for malaria control and eradication
... the pharmaceutical industry data are collected by the Centre for Medicines Research (CMR), but these cover a wide spectrum of infectious disease, and may miss malaria-specific ...
20
EVALUATION OF THE QUALITY OF SOME ANTIBIOTICS DISTRIBUTED IN ACCRA AND LAGOS
... Accra (Ghana) and Lagos (Nigeria) are two major cities with similar socio-economic settings in the West Africa sub region. Nigeria is known to have a long history of counterfeit antibiotics 6 . The National Agency for ...
10
Mass Spectrometric Structure Elucidation of the Trivalent and Pentavalent Nitrogen Contaminants of Pholcodine in the Cough Relief Medical Form Tuxidrin
... Weifa pharmaceutical company, and hence it no longer presents prob- lems to users and health authorities there; however, the medical form Tuxidrin, which contains a significant amount of pholcodine as the ...
6