Active Pharmaceutical Ingredients (APIs)
PRESENCE OF ORGANIC IMPURITIES INTO ACTIVE PHARMACEUTICAL INGREDIENTS: A REVIEW
... a pharmaceutical substance under investigation gives a maximum possible description of impurities present in ...in pharmaceutical products during the manufacturing process, chemical synthesis, formulation, ...
31
Crystal Engineering of Active Pharmaceutical Ingredients with Low Aqueous Solubility and Bioavailability
... the pharmaceutical industry have low aqueous ...these active pharmaceutical ingredients (APIs) is to use the crystal engineering technique of adding another molecule that disrupts the crystal ...
130
“GC and GC-MS Detection of Alkyl Mesylates in Active Pharmaceutical Ingredients” by N Balaji, Sayeeda Sultana, India.
... three active pharmaceutical ingredients [APIs: dolasetronmesylate (DOL), benztropinemesylate (BM), and dabigatranetexilatemesylate (DEM)] by a capillary gas chromatography method using flame ...
5
POLYMORPHISM AND SOLUBILITY OF SELECTED ACTIVE PHARMACEUTICAL INGREDIENTS
... of active pharmaceutical ingredients (APIs) and address the solubility, stability and hydration problems using the crystal engineering ...academicians, pharmaceutical scientists and US-FDA ...
15
Self-assembled sorbitol-derived supramolecular hydrogels for the controlled encapsulation and release of active pharmaceutical ingredients
... Active pharmaceutical ingredients (APIs) can be formulated into LMWGs using one of two strategies: (a) covalent conjugation and (b) physical ...
6
Regulatory Aspects of Cleaning and Cleaning Validation in Active Pharmaceutical Ingredients
... and active pharmaceutical ingredients (APIs) can be contaminated by other pharmaceutical products or APIs, by cleaning agents, by microorganisms or by other materials ...the ...
6
ELECTROSPRAY IONIZATION MASS SPECTROMETRY FRAGMENTATION PATHWAYS OF SALTS OF SOME 1,2,4 TRIAZOLYLTHIOACETATE ACIDS, THE ACTIVE PHARMACEUTICAL INGREDIENTS
... of active pharmaceutical ingredients, derivatives, 1,2,3-triazole-ylthio-acetate acids in case of two different voltages during fragmentation, ...
10
Sustainable Production of Highly Active Pharmaceutical Ingredients (HAPIs)
... Abstract- This paper deals with the sustainable and best methods that should be employed in the production of Highly Active Pharmaceutical Ingredients (HAPIs). We start with a brief introduction of ...
5
Study of technological properties of the active pharmaceutical ingredients for developing the combined medicine for neuropathy complex treatment
... of pharmaceutical development the technological properties of the initial active pharmaceutical ingredients and their combination (morphological properties of substances and their ...
5
Co-crystals: A novel approach to modify physicochemical properties of active pharmaceutical ingredients
... the active pharmaceutical ingredients and the bulk material properties can be modified, whilst maintaining the intrinsic activity of the drug ...of active pharmaceutical ...
12
Development and application of high resolution solid state NMR methods for probing polymorphism of active pharmaceutical ingredients
... The work presented in this thesis has focussed on the development of solid-state NMR techniques for studying the structure of crystalline organic molecules, specifically in application to the study of active ...
170
Assessment of active pharmaceutical ingredients in drug registration procedures in Pakistan : implications for the future
... the pharmaceutical drug registration process in Pakistan, to ensure good quality, safe, effective and affordable medicines are produced that will help improve patient care in Pakistan, and potentially boost ...
14
SULFONIC ACID COUNTER IONS QUANTIFICATION IN PHARMACEUTICALS BY ION CHROMATOGRAPHY
... three active pharmaceutical ingredients (API), namely acetate, mesylate, chloride, camphor sulfonate, trifluoroacetic acid, bromide, besylate, p-toluene sulfonate, phosphite, phosphate, ...
8
The production and sales of anti-tuberculosis drugs in China
... Results: First-line drugs were the majority in both sales (89.5 %) and production (92.3 %) of anti-TB drugs in China. The production of rifampicin held the majority share in active pharmaceutical ...
6
Enabling precision manufacturing of active pharmaceutical ingredients : workflow for seeded cooling continuous crystallisation
... the pharmaceutical industry and regulatory agencies as a means to pro- vide a consistent supply of ...rapid pharmaceutical process development with the associated constraints of speed to market and limited ...
32
Investigating effect of water of hydration on active pharmaceutical ingredients in a water-sensitive dosage form
... When pharmaceutical scien- tists purchase raw materials, caution for the impurity be- ing trapped in during manufacturing and purification processes must be ...
8
A NOVEL VALIDATED STABILITY INDICATING HPTLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF IRBESARTAN AND HYDROCHLOROTHIAZIDE IN ACTIVE PHARMACEUTICAL INGREDIENTS
... From the above resulting solution 8 µL of sample solution containing 1200 ng/spot of irbesartan and 100 ng/spot of hydrochlorothiazide were injected and from the peak area of irbesartan [r] ...
14
Enabling precision manufacturing of active pharmaceutical ingredients : workflow for seeded cooling continuous crystallisations
... the pharmaceutical industry and regulatory agencies as a means to pro- vide a consistent supply of ...rapid pharmaceutical process development with the associated constraints of speed to market and limited ...
32
Mind the gaps the epidemiology of poor quality anti malarials in the malarious world analysis of the WorldWide Antimalarial Resistance Network database
... APIs: Active pharmaceutical ingredients; IP: Intellectual property; GPHF-Minilab®: Global Pharma Health Fund; ACT: Artemisinin combination therapy; WHO: World Health Organization; USP: United States ...
14
A NOVEL RP HPLC METHOD FOR THE QUANTIFICATION OF CABOZANTINIB IN ACTIVE PHARMACEUTICAL INGREDIENTS AND PHARMACEUTICAL DOSAGE FORMS
... Materials: The active pharmaceutical ingredient and pharmaceutical dosage form were kindly gifted by Spectrum Laboratories, Hyderabad. HPLC grade water, acetonitrile is of Merck, Mumbai, and ...
7