Adefovir Dipivoxil
Initial combination anti viral therapy with lamivudine and adefovir dipivoxil decreases short term fatality rate of hepatitis B virus related acute on chronic liver failure
... Methods: In this retrospective study, 131 eligible ACLF patients, including 61 treated with 100 mg lamivudine and 10 mg adefovir dipivoxil daily and 70 not treated with any nucleoside analogs (NAs), were ...
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Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report
... Hypophosphatemic osteomalacia caused by proximal renal tubule dysfunction induces Fanconi’s syndrome, which leads to impaired reabsorption of amino acids, glu- cose, urate, and phosphate [1]. The chronic loss of phos- ...
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<p>Low-dose adefovir dipivoxil–induced hypophosphatemia osteomalacia in five chronic hepatitis B virus–infected patients. Is low-dose adefovir dipivoxil–induced nephrotoxicity completely reversible?</p>
... Abstract: Adefovir dipivoxil (ADV) is one of the most important nucleostide analogues currently in use for the treatment of chronic hepatitis B virus (HBV) ...
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Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B
... detoxication, removing blood heat from the liver, conditioning physical quality and eliminating jaundice, and has a significant effect in improving symptoms and signs of chronic hepatitis, protecting liver and lowering ...
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Adefovir dipivoxil induced hypophosphatemic osteomalacia in chronic hepatitis B: a comparative study of Chinese and foreign case series
... Adefovir dipivoxil (ADV) is a nucleotide analogue of adenosine monophosphate, which is effective in viral sup- pression for both treatment-naive and lamivudine-resistant chronic HBV-infected patients ...
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Case report Bilateral femoral head necrosis and pathological fractures resulted from Fanconi syndrome due to adefovir dipivoxil treatment: a case report and systematic analysis of 7 cases
... Abstract: We presented a case of a patient underwent bilateral total hip arthroplasty for femoral head necrosis and pathological femoral neck fracture resulted from adefovir dipivoxil related Fanconi ...
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De novo entecavir+adefovir dipivoxil+lamivudine triple-resistance mutations resulting from sequential therapy with adefovir dipivoxil, and lamivudine
... and adefovir dipivoxil were ...+ adefovir dipivoxil + lamivudine triple-resistance mutations were identified in 60 % (3/5) entecavir- naïve patients who received sequential therapy with ...
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Efficacy and resistance in de novo combination lamivudine and adefovir dipivoxil therapy versus entecavir monotherapy for the treatment naive patients with chronic hepatitis B: a meta analysis
... We searched the following databases: PubMed, Embase, Web of Science, The Cochrane Library, OVID, and CBM (Chinese Biological Medical Literature) until May 1, 2013. Of these databases, CBM database provides literature in ...
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Original Article Renal hypophosphatemia and osteomalacia during long-term therapy of adefovir dipivoxil in patients with chronic hepatitis B
... Hepatitis B virus (HBV) infection affects approx- imately two billion people worldwide, of which about 350 million people are chronically infect- ed [1]. To achieve sustained HBV DNA suppres- sion and persistent disease ...
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Case Report Hypophosphatemic osteomalacia induced by prolonged low-dose adefovir dipivoxil therapy for CHB two cases report and literature review
... Background: Adefovir dipivoxil (ADV) is a nucleotide used as a long-term therapy for chronic hepatitis B ...receiving adefovir for 10 years before the confirma- tion of ...from adefovir to ...
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Cost-effectiveness analysis of lamivudine, telbivudine, and entecavir in treatment of chronic hepatitis B with adefovir dipivoxil resistance
... Abstract: The purpose of this study was to analyze the cost-effectiveness of lamivudine (LMV), telbivudine (LdT), and entecavir (ETV) in treatment of chronic hepatitis B with adefovir dipivoxil (ADV) ...
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Detection of rtN236T mutation associated with adefovir dipivoxil resistance in Hepatitis B infected patients with YMDD mutations in Tehran.
... Adefovir dipivoxil (ADV) is a nucleotide analogue that interferes with the reverse transcriptase activity of hepatitis B virus (HBV) polymerase upon viral ...
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Meta analysis: Adefovir dipivoxil in combination with lamivudine in patients with lamivudine resistant hepatitis B virus
... Adefovir dipivoxil (ADV) as an oral prodrug of an acyclic monophosphate adenine analog, has gained popularity as a first-line treatment modality for patients with compen- sated hepatitis B, by virtue of its ...
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Adefovir dipivoxil is less expensive than lamivudine and associated with similar prognosis in patients with hepatitis B virus-related hepatocellular carcinoma after radical resection
... LAM and ADV are the most widely used nucleos(t)ide analogues in developing countries because they are much less expensive than novel analogues such as entecavir and tenofovir disopro[r] ...
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Clinical features of hypophosphatemic osteomalacia induced by long-term low-dose adefovir dipivoxil
... A cross-sectional analysis was carried out on patients who had been diagnosed with ADV-induced hypophosphatemic osteomalacia in Peking Union Medical College Hospital in recent 5 y[r] ...
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<p>Impact of antiviral therapy with nucleos(t)ide analog on survival of patients with HBV-related small hepatocellular carcinomas</p>
... Results: The data showed that 1-year, 3-year, 5-year overall survival rate of HBV-SHCC patients in NA-experienced group were 90.27%, 90.69%, 65%, NA-naïve group were 70.81%, 73.95%, 47.39%, and untreated group were ...
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Denosumab improves clinical manifestations of hypophosphatemic osteomalacia by adefovir induced Fanconi syndrome: a case report
... low-dose adefovir dipivoxil (10 mg/day) to treat chronic hepatitis B for approximately 5 ...by adefovir dipivoxil ...s adefovir dipivoxil dose and added calcitriol (active ...
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Effectiveness of Chinese herbal medicine in treating liver fibrosis: a systematic review and meta-analysis of randomized controlled trials
... Lu N, Xu Y, Cheng WN: Clinical research of adefovir dipivoxil tablets combined with Fufang Biejia Ruangan tablets on treating hepatic fibrosis following chronic hepatitis B. Chen FQ, Lin[r] ...
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In Vitro Drug Susceptibility Analysis of Hepatitis B Virus Clinical Quasispecies Populations
... The availability of oral nucleoside/nucleotide analog anti- hepatitis B virus (HBV) reverse transcriptase (RT) inhibitors has greatly improved the management of patients with chronic hepatitis B, a disease leading to 1 ...
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Hyperimmune anti-HBs plasma as alternative to commercial immunoglobulins for prevention of HBV recurrence after liver transplantation
... In this study we report our long-term experience with 21 patients with HBV-related end-stage liver disease (ESLD) who received HIP for prevention of HBV reinfection after LT. Patients underwent liver transplantation at ...
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