adenosine 5′-O-(γ-thio)triphosphate
Sequence-based prediction of permissive stretches for internal protein tagging and knockdown
... ADP: Adenosine diphosphate; AMP: Adenosine monophosphate; ASA: Absolute surface area; aTc: Anhydrotetracycline; ATP: Adenosine triphosphate; Bla: β -lactamase; CFX: Cell-free extract; CoS- ...
17
Effect of adenosine 5'-triphosphate and magnesium ions on citrate synthase.
... by 5*-AMP and 3'»5'- cyclic AMP, appears to rule out the direct participation of the purine residue in the observed inhibition of CS, Accordingly, experiments were carried out to see whether inorganic ...
65
Targeting cancer cell metabolism in pancreatic adenocarcinoma
... ADP, adenosine 5’-diphosphate; ATP, adenosine 5’-triphosphate; AA, amino acid; ASNS, asparagine synthetase; BCAA, branched-chain amino acid; CA, carbonic anhydrase; EGFR, epidermal ...
16
Uridine Triphosphate Thio-analogues Inhibit Platelet P2Y12 Receptors and Aggregation
... USA), Adenosine diphosphate (ADP) was from Enzo Life Science (Lörrach, Germany), 2-Thiouridine-5’triphosphate (2S-UTP), 4-thiouridine 5′-triphosphate (4S-UTP), ...uridine ...
14
Crosstalk between purinergic receptors and lipid mediators in leishmaniasis
... Macrophages and neutrophils possess several pattern recognition receptors (PRR) that respond to pathogen- associated molecular patterns (PAMPs) present in the Leishmania surface, such as lipophosphoglycan (LPG) and ...
9
In Silico Pharmacokinetics Studies for Quinazolines Proposed as EGFR Inhibitors
... Synthesis and Structure-Activity Relationships for 4-[Phenylmethylamino] and 4-Phenylamino Quinazolines as Potent Adenosine 5’-Triphosphate Binding Site Inhibitors of the Tyrosine Kinase[r] ...
10
Adenosine thiamine triphosphate and adenosine thiamine triphosphate hydrolase activity in animal tissues
... kinetic properties of AThTP hydrolase. Phos- phate buffer fits well for AThTP hydrolase assay, but its efficiency is limited by pH values of 6.2-8.2 (pk a = 7.2). Since the activity of AThTP hydrolase depends strongly on ...
12
Optical Aptasensors for Adenosine Triphosphate
... Because of extremely large surface-to-volume ratios, diverse surface morphologies and functionalities, high dispersibilities, and excellent size-dependent properties such as surface plasmon resonance and quantum ...
20
Evaluation of an adenosine 5' triphosphate assay as a screening method to detect significant bacteriuria
... There was 89.4% agreement between the culture method and the ATP assay, with 7.0% false positive and 27.0% false negative results from the ATP assay using 105 organisms/ml of urine or gr[r] ...
5
The quest for modernisation of traditional Chinese medicine
... Abbreviations APL: Acute promyelocytic leukaemia; ATP: Adenosine-5’-triphosphate; EMA: The European Medicines Agency; EU: European Union; FDA: The Food and Drug Administration of the Uni[r] ...
11
Sedative effects of peanut (Arachis hypogaea L ) leaf aqueous extracts on brain ATP, AMP, Adenosine and Glutamate/GABA of rats
... tate, Adenosine triphosphate (ATP), Adenosine mono- phosphate (AMP), Adenosine (Ad), γ-aminobutyric acid (GABA), and Glutamate (Glu) using HPLC (High per- formance liquid ...
6
Leishmaniasis and glycosaminoglycans: a future therapeutic strategy?
... capable of differentially activate PRRs to modulate and evade the immune response [3]. On its surface, Leishmania parasites express molecules that promote their binding to macrophages. One of them, glycoprotein 63 ...
12
The yin and yang functions of extracellular ATP and adenosine in tumor immunity
... ADO: Adenosine; ADP: Adenosine diphosphate; AMP: Adenosine monophos‑ phate; AMPK: AMP‑activated protein kinase; APCs: Antigen presenting cells; ATP: Adenosine triphosphate; BMDCs: Bone ...
11
Treatment with Oral ATP decreases alternating hemiplegia of childhood with de novo ATP1A3 Mutation
... Video-electroencephalography (EEG) revealed no simul- taneous changes during the hemiplegic spells. There were no metabolic abnormalities; lactic acid/pyruvic acid exercise tests were unremarkable; and EEG, magnetic ...
5
Anoxic metabolism and biochemical production in Pseudomonas putida F1 driven by a bioelectrochemical system
... 6.5 % and 4–17 % of NGAM, depending which literature value is assumed. Even if the lower value for NGAM is still an overestimation, it seems that an additional energy production must be present, to explain the ongoing ...
13
Detection of bacteriuria by luciferase assay of adenosine triphosphate
... Application of the method to 469 clinical urine specimens showed that the ATP level after treatment with Triton/apyrase was correlated to bacterial counts and that the sensitivity of the[r] ...
8
The CREST-E study of creatine for Huntington diseaseA randomized controlled trial
... Prespecified secondary measures included the UHDRS total motor score (TMS) and a composite of the verbal fluency, symbol digit modalities, and Stroop interference cognitive tests. The pri- mary tolerability measure was ...
10
Molecular and biochemical characterisation of the electron transport chain of plasmodium falciparum
... The oxidative phospholipid bilayer deterioration and mitochondrial dysfunction have been demonstrated to be caused by carbon and oxygen radical species (Gardner, 1989; Richter, 1987; Zhang et al., 1990). Shown in Figure ...
248
Keeping the heart in balance: the functional interactions of myoglobin with nitrogen oxides
... Among ectotherms, fish have been extensively studied and may contain several Mb isoforms, as found in carp (Fraser et al., 2006) and goldfish (Roesner et al., 2008) – two related hypoxia-tolerant species expressing Mb-1 ...
8
Adenosine Triphosphate Metabolism in Hereditary Spherocytosis
... However, when active transport is completely blocked by ouabain, there remains an increased rate of ATP and glucose consumption by HS red cells compared to normal, which suggests that no[r] ...
9