Adipose Tissue Derived Cytokines
Adipose tissue-derived cytokines and their correlations with clinical characteristics in Vietnamese patients with type 2 diabetes mellitus
... players in the pathogenesis of metabolic syndromes [34]. A decreased resistin concentration by knocking out the resistin encoding gene or blocking resistin by antibody could protect against obesity-associated hyperglyce- ...
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Human cord blood-derived platelet lysate enhances the therapeutic activity of adipose-derived mesenchymal stromal cells isolated from Crohn’s disease patients in a mouse model of colitis
... platelets derived from peripheral ...soft tissue repair if compared with the peripheral blood counterpart ...to tissue repair as indicated by histo- pathological analysis ...1 cytokines such ...
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Adipose tissue-derived stem cells show considerable promise for regenerative medicine applications
... an adipose tissue substitute enriched with stem ...large tissue loss or breast reconstruction, there have been attempts at their reconstruction using tissue engineering techniques with ...
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Intranasal mesenchymal stem cell secretome administration markedly inhibits alcohol and nicotine self-administration and blocks relapse-intake: mechanism and translational options
... anti-inflammatory cytokines and antioxidant molecules [8, ...secretome derived from adipose tissue MSCs activated in vitro in pro-inflammatory conditions results in a strong therapeutic effect ...
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Human adipose-derived stem cells for the treatment of intracerebral hemorrhage in rats via femoral intravenous injection
... and/or cytokines generated by the endogenous neural stem cells and the MSC in the ...of tissue damage or regeneration of lost nerve cells to facilitate motional improvement of the ICH induced rats, as ...
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Characterisation and comparison of adipose tissue macrophages from human subcutaneous, visceral and perivascular adipose tissue
... is upregulated during the late stages of monocyte dif- ferentiation [28] and serves as a scavenger receptor that binds different ligands, including oxidized low-density lipoprotein, oxidized phospholipids, long chain ...
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Current use of autologous adipose tissue-derived stromal vascular fraction cells for orthopedic applications
... cells. Adipose stem cells excrete a variety of cytokines, chemokines, growth factors, and exosomes [60, ...the tissue and differentiate into tissue- specific stem cells ...
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Plasticity of human adipose derived stem cells – relevance to tissue repair
... and adipose), it has been proposed that they harbor also myogenic capability (Rodriguez et ...been derived from MSCs using specific cocktails of cytokines and chemical compounds (Bekhite et ...
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Syngenic Adipose-Derived Stem/Stromal Cells Delivered in Decellularized Adipose Tissue Scaffolds Enhance In Vivo Tissue Regeneration Through Host Cell Recruitment
... and cytokines that include IL-1β, IL-6, and TNFα ...as tissue repair ...subtype-specific cytokines, and may be present in varying numbers based on the time course of tissue repair, and the ...
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Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta
... different tissue-derived ...angiogenic cytokines that could significantly promote the growth and tube formation of endothelial ...some tissue-derived MSC populations with potent ...
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Adipose tissue-derived mesenchymal stem cells and platelet-rich plasma: stem cell transplantation methods that enhance stemness
... factors, and bioactive molecules with trophic paracrine effects in response to local microenvironmental cues, and these factors are likely to mediate the main mech- anisms underlying the regenerative and repair potential ...
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Lymphatic transport of high density lipoproteins and chylomicrons
... Because it has proven more challenging than expected to under- stand the HDL cycle well enough to manipulate it therapeutically, significant attention should be focused on the half of apoA1- bearing HDL particles found ...
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The ratio of ADSCs to HSC-progenitors in adipose tissue derived SVF may provide the key to predict the outcome of stem-cell therapy
... to soluble factors, MSCs also secrete membrane-derived extracellular microvesicles (ExMVs), which may deliver messenger RNA, micro RNA, and proteins in order to communicate with the surrounding cells and ...
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Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease
... of cytokines and chemokine re- ceptors may be disease specific, such as interferon gamma (IFNγ) and CXCR3 in NME, and IL-17 and CCR2 in GME ...[34]. Cytokines have also been implicated in the phenotype ...
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First-in-man intravenous implantation of stromal vascular fraction in psoriasis: a case study
... As stem cell therapy is a novel approach and the full mechanisms of action are not fully understood, it is unclear to what extent this therapy may facilitate tissue repair or reverse the effects of autoimmune ...
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The Co-Delivery of Syngeneic Adipose-Derived Stromal Cells and Macrophages on Decellularized Adipose Tissue Bioscaffolds for In Vivo Soft Tissue Regeneration
... pre-differentiated ASC-seeded constructs into severe combined immunodeficient (SCID) mice enhanced macroscopic vascularization, retention of scaffold volume, and quantitatively greater levels of lipid accumulation after ...
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The Current Perspectives of Stem Cell Therapy in Orthopedic Surgery
... After high-energy trauma or gunshot injuries, bone de- fects may occur from extrusion of bony fragments. Bone defects are one of the major challenging situations of or- thopedic surgery. In this area, the first stem cell ...
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Safety of adipose-derived cell (stromal vascular fraction – SVF) augmentation for surgical breast reconstruction in cancer patients
... fat tissue between the breast skin and the chest ...connective tissue diseases, chronic anticoagulants treatment (<15 days before the therapy), body mass index (BMI) >30, contraindications for ...
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Clinical analysis of selected complement derived molecules in human adipose tissue
... We would also like to highlight our observation that in human AT strong correlations between selected complement-derived molecules (mainly C5b-9/MAC) and SDF-1 are observed. This cross-talk between C5b-9/ MAC and ...
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Fracture Healing Effects of Locally Administered Adipose Tissue Derived Cells
... fore, the healing effect of locally administered ADCs may be attributed to cytokine production and humoral effects, rather than direct cellular proliferation and differentiation into osteoblasts and stromal cells. ...
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