Adverse Drug Event
Methods for evaluating adverse drug event preventability in emergency department patients
... toxic drug serum concentration or abnormal lab results (which re- viewers felt did not equate to the events being always definitely preventable; Table ...the adverse drug ...
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Labeling an Adverse Drug Event “Preventable”
... This case also raises at least two critical questions about the patient-physician relationship and the appropriate response to a preventable adverse event: what is the extent of Dr. McKinley’s duty to Mr. ...
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Concordance and predictive value of two adverse drug event data sets
... Methods: We systematically evaluated the concordance of two widely used ADE data sets – Lexi-comp from 2010 and SIDER from 2012. The strength of the association between ADE (drug) counts in Lexi-comp and SIDER was ...
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Adverse Drug Event prediction combining shallow analysis and machine learning
... the Adverse Drug Reactions (ADRs) in EHRs in order to alleviate the work-load to sev- eral services within a hospital (pharmacy service, documentation ...reports. Event detection was thoroughly ...
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Extracting Adverse Drug Event Information with Minimal Engineering
... like drug names or drug attributes, includ- ing dosages, routes, and adverse events are entity- like spans, while the pairing of attributes and drugs are naturally represented as relations to be ex- ...
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Representing Clinical Notes for Adverse Drug Event Detection
... An advantage of using the terms representation is that, in comparison to the other representations – in particular the distributed ones – it lends itself to some degree of interpretability. While random forest belongs to ...
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Standardizing adverse drug event reporting data
... input drug names before MedEx-based annota- ...200 drug names and annotated them using the RxNorm ...lected drug names, using P = TP/(TP + FP), R = TP/(TP + FN), and F = 2PR/(P + R), in which TP ...
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Predictive modeling of structured electronic health records for adverse drug event detection
... In this study, we investigated the use of various data types in EHRs for drug safety surveillance. Here, we focused on using the structured data to build predictive models using machine learning based methods. ...
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Evaluating the risk of patient re-identification from adverse drug event reports
... Previous work has assumed that an adversary would have prior knowledge which she uses to re-identify a sin- gle record. There is also work considering prior knowledge by the adversary about multiple records in the ...
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Early Event Detection and Discontinuation of the Culprit Drug Increases the Rate of Survival in Severe Cutaneous Adverse Drug Reactions: A Multi-Center Study in Bangladesh
... An adverse drug event (ADE) can be defined as an injury resulting from medical intervention related to a drug (Kohn et ...An adverse drug reaction (ADR) is a medication-induced ...
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Adverse Effect Relations Extraction from Massive Clinical Records
... extract adverse drug event and effect (adverse–effect) relations from massive clinical ...records. Adverse–effect rela- tions share some features with relations proposed in previous ...
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Clinical interventions in Australian community pharmacies
... Code Primary domains VS.01 Pl Adverse reactions Patient suffers from an adverse drug event P2 Drug Choice Problem Pati~nt gets or is going to gd a wrong or no drug drug for his/her disea[r] ...
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The Emergency Division as a strategic center for pharmacovigilance activities. The role of hospital pharmacist experience at the Hospital *Gaetano Rummo* of Benevento
... (adverse drug reaction) or ADE (adverse drug event), the percen- tage of hospital admissions due to acute ADR and ADE, suspected drugs which caused reaction and other drugs took in ...
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Incidence and predictors of major adverse drug events among drug resistant tuberculosis patients on second line anti tuberculosis treatment in Amhara regional state public hospitals; Ethiopia: a retrospective cohort study
... excessive Adverse Drug Events (ADE) than first line anti-TB drugs, which in turn make the successful treatment of TB a ...An adverse drug event was defined as any untoward medical ...
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<p>Comparison of Adverse Event Profiles of Tumor Necrosis Factor-Alfa Inhibitors: Analysis of a Spontaneous Reporting Database</p>
... unexpected adverse events could occur because patients have various backgrounds and etiologies, unlike in clinical trials, where enrollment criteria are ...unexpected adverse drug effects can emerge, ...
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Assessments of harms in clinical trials
... the drug, the usage of the drug, how long the drug has been on the market, the year of its introduction and whether there has been any publicity about the ...(i.e. drug use is not known, and ...
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Adverse event reporting in adult intensive care units and the impact of a multifaceted intervention on drug-related adverse events
... for adverse events (AEs) that could occur due to the complexity of care, the large number of inter- ventions performed, and the patients’ fragile medical conditions ...
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Mortality and oral anticoagulants in the Food and Drug Administration Adverse Event Reporting System
... We deliberately focused our analyses exclusively on mortality for three major reasons. First, death is the most important outcome measure validating the effi- cacy of any drug in general, and NOACs in particular. ...
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Dextromethorphan: a case study on addressing abuse of a safe and effective drug
... the Drug Enforcement Administration (DEA) in 2007 requested that FDA evalu- ate whether DXM should be recommended for scheduling under the Controlled Substances Act ...
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Effect of database profile variation on drug safety assessment: an analysis of spontaneous adverse event reports of Japanese cases
... comparisons between other countries. There are limitations in demonstrating the association between variances in regula- tions and databases. Spontaneous reporting system databases mostly depend on the compliance of ...
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