Age-related cataract genesis
Glutathione S-Transferase GSTM 1, Null Genotype May Be Associated with Susceptibility to Age-Related Cataract
... to cataract formation [3, ...glaucoma, cataract and other eye diseases by resulting in a number of molecular changes in the eye [3, 5, 6, ...patho- genesis of cataract is this peroxidative ...
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Ultraviolet-B induces ERCC6 repression in lens epithelium cells of age-related nuclear cataract through coordinated DNA hypermethylation and histone deacetylation
... Exposure of the lens to UVB induces DNA lesion and oxidative stress [11, 17]. Oxidative stress-induced DNA damage is considered an important factor in the patho- genesis of ARNCs [18, 19]. There are several ...
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Different alpha crystallin expression in human age-related and congenital cataract lens epithelium
... between age-related and congenital cataracts, the regula- tory factors may differ ...congenital cataract than in the age-related cataract ...
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Effects of cataract surgery and intra-ocular lens implantation on visual function and quality of life in age-related cataract patients: a systematic review protocol
... Strategies will be designed to identify all relevant studies for HRQoL among age-related cataract patients. We will search the bibliographic electronic databases like the Cochrane Library including ...
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A post trial survey to assess the impact of dissemination of results and unmasking on participants in a 13 year randomised controlled trial on age related cataract
... Concerns have been raised that participants in trials could be stressed [6] or even harmed [8,9] by provision of personal and/or of general study results [15]. Possible emotional harmful effects include: reliving ...
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... of cataract. Patient were ( with cataract and controls) matched by sex and years of ...of cataract was established by complete ocular ...with age related cataract and ...of ...
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Challenges for the cataract surgeon treating people with dementia: a qualitative study exploring anesthetic choices
... “If you ask me about people who need a general anesthetic, so that they really are unable to comprehend what was going on; I don’t think I have ever operated on anyone that bad. I think for the simple reason in order to ...
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Studies on in situ gelling system for better ocular drug therapy.
... This universe is very beautiful because we can see it, we can feel it. Imagine your life without your eyes. Every five seconds one person in the world goes blind and a child goes blind every minute. According to the ...
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Patterns of gene expression in microarrays and expressed sequence tags from normal and cataractous lenses
... cause. Cataract can be formed together with other devel- opmental disorders depending on mutations of factors that play roles in the differentiation of the lens, such as Pitx3 [136], crystallins, ferritin, ...
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Lifetime exposure to ambient ultraviolet radiation and the risk for cataract extraction and age-related macular degeneration : the Alienor Study
... Published on October 21, 2014 as Manuscript iovs.14-14471 1 Lifetime exposure to ambient ultraviolet radiation and the risk for cataract 2 extraction and age-related macular degeneration[r] ...
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Posterior segment causes of reduced visual acuity after phacoemulsification in eyes with cataract and obscured fundus view
... patient dissatisfaction after phacoemulsification, apart from being common premorbid conditions in patients presenting for cataract surgery. However, in both studies, the presence of these pathologies was ...
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Fruit, vegetable, and dietary antioxidant intake and age-related cataract risk: A case-control study
... of age-related cataract ...of cataract, which is in line with the results of previous studies (2, ...of cataract (23). However, the Age- Related Eye Disease Study found no ...
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A retrospective cohort study of clinical outcomes for intravitreal crystalline retained lens fragments after age-related cataract surgery: a comparison of same-day versus delayed vitrectomy
... received cataract surgery) is correlated with the treatment (no non-MCF cataract surgery patients received a same-day ...had cataract surgery at MCF were more likely to have been referred by other ...
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The Sight Loss and Vision Priority Setting Partnership (SLV-PSP): overview and results of the research prioritisation survey process
... The detailed methods for this prioritisation process have been described in detail elsewhere. 4 In brief, the process comprised fi ve stages ( fi gure 1). Our study did not require ethical approval or consent from ...
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Association of alpha A-crystallin polymorphisms with susceptibility to nuclear age-related cataract in a Han Chinese population
... Age-related cataracts (ARCs), which are a major cause of blindness worldwide, are characterized by lens opaci- ties and visual impairment due to degenerative changes in the lens in the elderly [1]. The ...
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The LEGSKO Mouse: A Mouse Model of Age-Related Nuclear Cataract Based on Genetic Suppression of Lens Glutathione Synthesis
... with age and is highly elevated in cataractous lenses, with over 50% of membrane bound protein methionine present in oxidized form ...with age as measured at 9 months compared to 3 months of age ...
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Rapid action to avoid cataract blindness in South Sulawesi
... with cataract as the main causes of blindness ...for cataract blindness control in South Sulawesi within the last 3 years (2014 - ...of cataract infrastructures, human resources, and cataract ...
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ESTIMATION OF SERUM ELECTROLYTES (NA+ AND K+) AND SERUM CALCIUM LEVELS IN SENILE CATARACT PATIENTS AND ITS COMPARISON WITH NON CATARACT PATIENTS
... eye. Age is considered as one of the strongest known risk factor for cataract ...for cataract formation is serum sodium and serum calcium, although serum potassium is ...senile cataract ...
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Evaluating vision-related quality of life in preoperative age-related cataract patients and analyzing its influencing factors in China: a cross-sectional study
... preoperative cataract patients who matched the inclusion criteria were recruited for this ...as age-related cataract(s) without other major eye diseases, such as glaucoma, macular ...
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Original Article The relationship of DNA repair gene XPD, XRCC1, OGG1, APE1, and WRN polymorphism with the risk of age-related cataract in Hani people from Mojiang region in Yunnan
... Abstract: Age-related cataract (ARC) is the leading cause of blindness in the elderly. This study investigated DNA repair genes, XPD, XRCC1, OGG1, APE1, and WRN single nucleotide polymorphisms ...
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