airway epithelial cell
Airway epithelial cell tolerance to Pseudomonas aeruginosa
... with epithelial cells (see [48] for ...the airway epithelial surface ...than cell lines grown directly on plastic. However, well-characterized cell lines facilitate mechanistic studies, ...
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Culturing the Unculturable: Human Coronavirus HKU1 Infects, Replicates, and Produces Progeny Virions in Human Ciliated Airway Epithelial Cell Cultures
... human airway epithelium, a likely initial site for coronavirus inoculation and ...ciliated airway epithelial cell ...bronchial airway epithelial cells and mirrors the morphology ...
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PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema
... Additional file 2: Figure S1. Neutrophil elastase (NE) increases placenta growth factor (PlGF) expression in endothelial cell. BAEC and fibroblast were treated with neutrophil elastase (NE) (0 – 300 mU/ml) for 24 ...
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Airway epithelial cell expression of interleukin 6 in transgenic mice Uncoupling of airway inflammation and bronchial hyperreactivity
... We produced transgenic mice which overexpress human IL-6 in the airway epithelial cells. Transgenic mice develop a mononuclear cell infiltrate adjacent to large and mid-sized airways. ...
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Epilysin (matrix metalloproteinase-28) contributes to airway epithelial cell survival
... We observed that A549 cells expressing wild-type MMP28 had increased survival rates during serum-deprivation compared to cells expressing mutant or no MMP28. After 6 days in serum-free medium, only wild-type clones ...
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Differentiated transplant derived airway epithelial cell cytokine secretion is not regulated by cyclosporine
... the airway epithelium to injury and disordered repair in the pathogenesis of BOS may be stimulation of fibroblast proliferation, a process that can be mediated by growth factors such as ...
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Activation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione
... nasal epithelial cells obtained from delF508 homozygous CF ...different airway effects, and its levels are low in the CF airway; CF and other airways diseases may therefore represent, at least in ...
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Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes
... (eosinophilia, airway epithelial cell injury, regenerative goblet cell hyperplasia, bronchocentric pulmonary fibro- sis, and atelectasis) induced by a single installation of ...and ...
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TRAIL (CD253) Sensitizes Human Airway Epithelial Cells to Toxin-Induced Cell Death
... ricin-induced cell death is of particular interest, considering that TRAIL activates cell death through an extrinsic apoptotic pathway, whereas ricin triggers intrinsic pathways induced as a result of the ...
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Airway epithelial homeostasis and planar cell polarity signaling depend on multiciliated cell differentiation
... an epithelial scratch wound (3, 40) (effect variable among donors, Figure 7, C and D, and Supplemental Figure ...CF airway epithelium in ...of airway epithelial cell ...
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Effect of Host Modification and Age on Airway Epithelial Gene Transfer Mediated by a Murine Leukemia Virus-Derived Vector
... well-differentiated airway epithelial cell cultures for 2 h was not associated with a significant loss of transduction efficiency when the previously incubated vector was used to transduce naive CFT1 ...
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pats.200805-041hr.pdf
... small airway epithelial renewal is administra- tion of naphthalene to mice, which causes death of the majority of the Clara cell population due to selective metabolic activa- tion of the ...the ...
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Production of the novel C C chemokine MCP 4 by airway cells and comparison of its biological activity to other C C chemokines
... MCP-4 (previously referred to as CK b 10) which was discov- ered via large-scale cDNA sequencing by Human Genome Sciences. Preliminary screens among 10 novel chemokines identified by this method indicated that MCP-4 is a ...
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0947-10.pdf
... ciliated airway epithelial cell cultures (HAE) that recapitulate the morphology, biochemistry, and physiology of the human airway epithe- lium, the apical surfaces of HAE were inoculated with ...
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Influenza Virus Receptor Specificity and Cell Tropism in Mouse and Human Airway Epithelial Cells
... tracheal epithelial cells, lung sections, and an in vivo mouse model, and we de- termined the human relevance using a human in vitro airway epithelial cell model and human lung ...ciliated ...
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Respiratory viral infections and host responses; insights from genomics
... in airway epithelial cells found that RV-induced IFN-β and IFN-λ responses were impaired in subjects with asthma, leading to in- creased viral replication and shedding and exaggerated secondary responses ...
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Effect of vitamin D3 on the antimicrobial activity of human airway surface liquid: preliminary results of a randomised placebo-controlled double-blind trial
... human airway epithelial cell cultures on the gene expression of cathelicidin in response to vitamin D 3 and expression of CYP27B1 (1-alpha hydroxylase), responsible for vitamin D 3 ...
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Endosomal processing limits gene transfer to polarized airway epithelia by adeno associated virus
... of cell-surface receptors (9) and/or receptor ligands in the viral coat (10, ...of airway epithelia are not the major rate-limiting factors in transduction of this tissue ...other airway diseases, ...
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Allergen induced IL 9 directly stimulates mucin transcription in respiratory epithelial cells
... The identity of accessory factors remains unknown. Obvious sources are proteins other than Th2 cytokines present in the active fractions of airway fluid. For exam- ple, IL-8 (8 kDa) was abundant in our asthmatic ...
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Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation
... goblet cell metaplasia and Th2 inflammation in neonatal ...human airway epithelial cells in vitro, FOXA3 induced SPDEF and caused goblet cell metapla- sia ...goblet cell metaplasia in ...
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