Anaplastic Thyroid Carcinoma
Locally Advanced Anaplastic Thyroid Carcinoma with Long Term Survival of More Than 7 Years after Combined Surgery Including Tracheal Resection and Radiotherapy: Case Report
... Background: Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignan- cies with a mean survival time of 6 months regardless of ...advanced anaplastic thyroid ...
8
Evidence from an updated meta-analysis of the prognostic impacts of postoperative radiotherapy and chemotherapy in patients with anaplastic thyroid carcinoma
... Two investigators (WW and QX) searched PubMed, Embase, Web of Science, VIP Database for Chinese Technical Periodicals, Wanfang Data Knowledge Service Platform, and China National Knowledge Infrastructure (CNKI) for ...
7
Salvage pembrolizumab added to kinase inhibitor therapy for the treatment of anaplastic thyroid carcinoma
... Background: Anaplastic thyroid carcinoma (ATC) is a rare but deadly form of thyroid cancer. Kinase inhibitors kinase inhibitors have shown clinical efficacy in the management of ATC, however, ...
10
Simultaneous occurrence of distant metastases to the small intestine and the thoracic esophagus from anaplastic thyroid carcinoma: a case report
... Anaplastic thyroid carcinoma (ATC) is an aggressive malignancy and characterized by spreading to regional lymph nodes and distant metastases, but we were unable to find a previous report of ...
6
<p>BRMS1 downregulation is a poor prognostic biomarker in anaplastic thyroid carcinoma patients</p>
... Thyroid cancer (TC) is the most common malignancy of the endocrine system. 1 For most TC patients, the standard treatment (surgery followed by either radioactive iodine or observation) can promise an excellent ...
9
Diagnosis and Treatment of Anaplastic Thyroid Carcinoma
... detecting thyroid malignancies. FNAC should be performed in any thyroid nodule >1 cm and in those <1 cm if there is any clinical (history of head and neck irradiation, family history of thyroid ...
5
Targeting ubiquitin-specific protease 22 suppresses growth and metastasis of anaplastic thyroid carcinoma
... ATC, anaplastic thyroid carcinoma; BMI-1, B-cell- specific murine leukemia virus integration site-1; cl- caspase-3, cleaved caspase-3; DAB, diaminobenzidine; DAPI, 4ʹ, 6-diamidino-2-phenylindole; ...
13
Anaplastic Thyroid Carcinoma: A Therapeutic Dilemma
... 25. Franzen A, Heldin NE. BMP-7 induced cell cycle arrest of anaplastic thyroid carcinoma via p21(CIP1) and p27 (KIP1). Biochem Biophys Res Commun 2001;285:773-81. 26. Greenberg VL, Wiliams JM, ...
6
Long Term Survival in a Patient with Anaplastic Thyroid Carcinoma Treated with Cricotracheal Resection
... Airway management is another significant issue in- volved in treatment of these patients. Of all malignancies, anaplastic thyroid carcinoma most commonly requires tracheostomy as part of management ...
5
Original Article Immunohistochemical detection of epithelial- mesenchymal transition associated with stemness phenotype in anaplastic thyroid carcinoma
... neoplastic thyroid tissue. This suggests that the anaplastic thyroid carcinoma cells arise via epithelial-mesenchymal transition from differen- tiated thyroid carcinoma and in ...
8
Imaging of Anaplastic Thyroid Carcinoma
... SUMMARY: Anaplastic thyroid carcinoma is fatal if ...of anaplastic thyroid carcinoma in 57 patients. Anaplastic thyroid carcinoma presented as a large neck ...
5
CT evaluation of anaplastic thyroid carcinoma
... As already reported [1, 3, 15], anaplastic thyroid carcinoma in our study often invaded neighboring structures such as the carotid artery 37%, internal jugular vein 53%, larynx 32%, trac[r] ...
7
Original Article PUMA enhances sensitivity of anaplastic thyroid carcinoma cells to cisplatin
... p53 upregulated modulator of apoptosis (PU- MA) as a BH3-only Bcl-2 family protein plays an essential role in p53-dependent and -indepen- dent apoptosis [8, 9]. PUMA deficiency blocks apoptotic responses to p53 ...
9
Biochemical aspects of the combined use of taxanes, irradiation and other antineoplastic agents for the treatment of anaplastic thyroid carcinoma
... way (PIK3CA, PTeN, PIK3C2G, PIK3CG, PIK3C3, PIk3r1, PIk3r2, akT3, TSC1, TSC2, mTOr), SWI- SNF nucleosome remodeling complex (arId1a, arId1B, arId2, arId5B, SMARCB1 , PBrM1, ATRX), DNA mismatch repair genes (MSh2, MSh6, ...
14
18F-FDG PET/CT in the diagnosis of tumor thrombus from anaplastic thyroid carcinoma in a young boy
... Coronal PET/CT (A) and CECT (B) image showing FDG avid thyroid mass (long thin arrows) with bilateral internal jugular vein thrombosis (short thick arrows) showing superior extension up[r] ...
5
FOXA1 is a potential oncogene in anaplastic thyroid carcinoma
... differentiated thyroid carcino- mas did not show detectable expression of ...follicular thyroid tissues, still not well understood in terms of potential transition to undifferentiated thyroid ...
10
Anaplastic thyroid carcinoma diagnosed after treatment of lenvatinib for papillary thyroid carcinoma
... that anaplastic transformation of PTC was ...in thyroid tumors, p53 gene inactivation, which is a late event in the carcinogenic process and occurs together with a marked increase in cell proliferation, ...
5
Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors
... Anaplastic thyroid carcinoma (ATC) is the most aggressive form of thyroid cancer, and often derives from pre-existing well-differentiated ...of thyroid cancer-related deaths, due to its ...
18
Prevalence and pattern of thyroid malignancy in thyroid nodule in Aseer Central Hospital in KSA
... Conclusions: Thyroid nodule is a common clinical problem and the proportion of such nodules that prove to be malignant is not small, investigations are of immense help to corroborate with the clinical and ...
5
Novel treatments for advanced thyroid cancer and elucidation of biomarkers
... (DTC), anaplastic (ATC) and advanced medullary thyroid cancer ...persistent thyroid cancer is merely based on the molecular unraveling of the carcinogenesis pathways implicated in thyroid ...
151