anti-cancer drug
ELECTROCHEMICAL OXIDATION AND DETERMINATION OF AN ANTI CANCER DRUG PEMETREXED DISODIUM
... of anti-cancer drug PTD has been investigated at glassy carbon electrode using voltammetric ...of anti-cancer drug PTD was ...
5
Chemoresistance of Cancer Cells: Requirements of Tumor Microenvironment-mimicking In Vitro Models in Anti-Cancer Drug Development
... efficacious drug candidates might be eliminated during early screening, and compounds with lower or no clinical efficacy might progress into clinical trials, resulting in increased developmental cost and ...vitro ...
17
Comparison of responsiveness to cancer development and anti-cancer drug in three different C57BL/6N stocks
... effective anti-cancer drug discovered in 1965, proven to have anti-cancer activity in mouse models and used in the treatment of solid tumors such as testicular cancer, ovarian ...
10
Molecular chess? Hallmarks of anti cancer drug resistance
... of anti-cancer drug resistance. The advent of anti-CTLA antibody treatment with ipilimumab in melanoma [84] showed that the promise was likely to be fulfilled, and the success of ...
8
Metformin as a new anti-cancer drug in adrenocortical carcinoma
... vitro anti-proliferative effect of metformin in preclinical models is obtained by using higher doses than those reached in diabetic patients [49], thus apparently limiting its potential use in cancer ...
13
LESS TOXIC NANOPARTICLES OF PLATINUM BASED ANTI CANCER DRUG
... Toxicity Studies: Rats administered (i.p.) with eudragit cisplatin nanoparticles shows no mortality in 24 h, the first death observed was after 24 h and the second, third death was after 45 h these animals show the signs ...
16
Fabrication and evaluation of gelatin nanoparticles for delivering of anti - cancer drug
... SEM and AFM analyze, the protein nanoparticle as it has been assembled herein, not only mimics the size and surface chemistry of nanoparticles such as viruses and plasmid, but also can be used as drug delivery ...
8
Evaluation of Anti Oxidant Status and Radioprotective Activity of a Novel Anti Cancer Drug in Mice
... bles 7 and 8) when compared to the irradiated animals. In the present study, the effect of the different treat- ments on some haematological indexes was evaluated and the results were depicted in (Tables 9 and 10). The ...
13
Targeted drug delivery of anti cancer drug by applying gastro retentive systems and its pharmacological evaluation.
... gastric cancer are typically men (male: female ratio ...gastric cancer is diagnosed, it is usually ...gastric cancer are similar to those of peptic ulcer ...gastric cancer is still in the ...
317
Extracellular vesicles and anti cancer drug resistance
... Approximately 30 years ago, exosomes were described as involved in reticulocyte maturation by transporting transferrin receptor out of the cell [35]. Building on this knowledge, over recent years increasing evidence ...
14
Dissolution characteristics of anti cancer drug Cytarabine
... Cytarabine is an effective drug for the treatment of leukemia. In this paper, the dissolution behavior of Cytarabine in normal saline and citric acid solution was studied using microcalorimetry in order to obtain ...
5
Three Protocols Designed to Individualize and Maximize Anti Cancer Drug Therapy
... similar drug limiting hematologic ...the drug received ...the drug, an increased ca- pacity of the hematopoietic system to resist the drug, or both, is ...
11
Journal of Applied Pharmaceutical Science
... Four novel Polyhedral Oligomeric Silsesquioxane (POSS) particles were tested for biocompatibility for a promising application in anti-cancer drug delivery. We previously investigated the interference ...
5
Polyurethane membrane with porous surface for controlled drug release in drug eluting stent
... crease drug release because porous structure had larger surface ...of drug from porous PU membranes increases the potential usefulness of a bare metal stent cover to limited drug release of hydro- ...
5
Superparamagnetic reconstituted high-density lipoprotein nanocarriers for magnetically guided drug delivery
... 7.5 mg/mL, free cholesterol 0.175 mg/mL and cholesteryl oleate 0.075 mg/mL, all from previously prepared stocks, were added and mixed thoroughly. This mixture was then dried under nitrogen. To this mixture, 1 mg/mL ...
12
Evaluation of Anti Diabetic Drug Alogliptin for the Treatment of Cancer in Rats
... diabetic drug) in which variety of pharmacological features are ...date anti-cancer activities of this Drug have not been ...of anti-cancer activities in experimental animal ...
17
Fertilité masculine après chimiothérapie: à propos d’une série de 26 patients traités pour cancer du testicule stade 1
... : Reproductive effects of anti-cancer drug, cyclophosphamide in male rats at differents ages.. : Reproductive effects of anti-cancer drug, procarbazine in male rats at di[r] ...
6
Effect of polyunsaturated fatty acids on drug-sensitive and resistant tumor cells in vitro
... the anti-cancer ...vincristine drug uptake and decrease in its efflux (vincristine) by tumor cells that could result in higher intracellular concentration(s) of the anti-cancer ...
35
Synthesis of a reactive oxygen species-responsive
... acid functional group is coupled to the native primary amine of the anti-cancer drug doxorubicin. The presence of a 143[r] ...
5
Systemic delivery of the anticancer agent arenobufagin using polymeric nanomicelles
... plasma drug concentrations at all time points except for 5 and 360 minutes (Figure ...elevated drug plasma ...enhanced drug exposure by ABG-PNs may be associated with reduced body ...
9