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Anti-cytokine monoclonal antibodies

Anti-CD19 Monoclonal Antibodies: a New Approach to Lymphoma Therapy

Anti-CD19 Monoclonal Antibodies: a New Approach to Lymphoma Therapy

... Fc-engineered anti-CD19 XmAb5871 inhibits humoral immune responses ...proliferation, cytokine, and IgG synthesis that are induced by both BCR and TLR9 ...

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New application of anti-TLR monoclonal antibodies: detection, inhibition and protection

New application of anti-TLR monoclonal antibodies: detection, inhibition and protection

... Monoclonal antibody (mAb) is an essential tool for the analysis in various fields of biology. In the field of innate immunology, mAbs have been established and used for the study of Toll-like receptors (TLRs), a ...

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New horizons for the treatment of severe, eosinophilic asthma: benralizumab, a novel precision biologic

<p>New horizons for the treatment of severe, eosinophilic asthma: benralizumab, a novel precision biologic</p>

... circulating cytokine, and the second was to interfere with the IL-5R α on ...Both anti- IL5 monoclonal antibodies (mAbs) (mepolizumab and resli- zumab) and anti-IL5R α (benralizumab) ...

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A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis

A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis

... vivo cytokine production was previously described ...bilized anti-CD3 and anti-CD28 monoclonal antibodies (anti-CD3/anti-CD28; Dynabeads Human T-Activator, Invitrogen, ...

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Plasmapheresis, Anti-ACE2 and Anti-Fc&gamma;RII Monoclonal Antibodies: A Possible Treatment for Severe Cases of COVID-19

<p>Plasmapheresis, Anti-ACE2 and Anti-Fc&gamma;RII Monoclonal Antibodies: A Possible Treatment for Severe Cases of COVID-19</p>

... and release of cytokines (cytokine storm) following in fl uenza virus infection can increase the severity of the disease. 13 Also, it is known that several viral diseases are mediated by anti- body-dependent ...

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Monoclonal yeast killer toxin-like candidacidal anti-idiotypic antibodies.

Monoclonal yeast killer toxin-like candidacidal anti-idiotypic antibodies.

... Serological assay of KT-IdAbs. The serological assay of the product of cloned hybridomas was carried out by an inhibition-competitive enzyme-linked immu- nosorbent assay (ELISA) by a previously described procedure ...

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IL 17A and IL 17F do not contribute vitally to autoimmune neuro inflammation in mice

IL 17A and IL 17F do not contribute vitally to autoimmune neuro inflammation in mice

... graph shows the development of EAE according to clinical scores (n = 10; SEM as indicated) in 1 out of 2 independent experiments. (B and C) Th17-cytokine profile measured by ELISA of splenocytes isolated from mice ...

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The combination of anti-KIR monoclonal antibodies with anti-PD-1/PD-L1 monoclonal antibodies could be a critical breakthrough in overcoming tumor immune escape in NSCLC

The combination of anti-KIR monoclonal antibodies with anti-PD-1/PD-L1 monoclonal antibodies could be a critical breakthrough in overcoming tumor immune escape in NSCLC

... To our knowledge, this is the first study to analyze the correla- tions between PD-1 and KIR. We observed KIR expression before and after anti-PD-1 monoclonal antibody treatment. We found that the ...

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Quantitative ELISAs for serum soluble LHCGR and hCG-LHCGR complex: potential diagnostics in first trimester pregnancy screening for stillbirth, Down’s syndrome, preterm delivery and preeclampsia

Quantitative ELISAs for serum soluble LHCGR and hCG-LHCGR complex: potential diagnostics in first trimester pregnancy screening for stillbirth, Down’s syndrome, preterm delivery and preeclampsia

... LHR74 antibodies were initially pro- vided by Dr Hugues Loosfelt (INSERM, France) and subsequently the antibody producing clones were obtained from ATCC (Clone ID CRL-2685 and CRL- ...2686). Antibodies ...

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Trypanosoma cruzi Bromodomain Factor 3 Binds Acetylated α-Tubulin and Concentrates in the Flagellum during Metacyclogenesis

Trypanosoma cruzi Bromodomain Factor 3 Binds Acetylated α-Tubulin and Concentrates in the Flagellum during Metacyclogenesis

... specific antibodies diluted in PBS for 3 h. The antibodies used were polyclonal rabbit and mouse anti-TcBDF3, monoclonal mouse anti-acetylated ␣ -tubulin antibody clone 6-11B-1 ...

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Novel Antibody Lectin Enzyme Linked Immunosorbent Assay That Distinguishes Prion Proteins in Sporadic and Variant Cases of Creutzfeldt Jakob Disease

Novel Antibody Lectin Enzyme Linked Immunosorbent Assay That Distinguishes Prion Proteins in Sporadic and Variant Cases of Creutzfeldt Jakob Disease

... specific for the N-linked glycans. We also depleted the full- length PrP species in the brain homogenates with MAb 8B4- conjugated beads prior to the MAb 8B4-lectin ELISA. Re- moval of the full-length PrP species also ...

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Use of mouse anti rabies monoclonal antibodies in postexposure treatment of rabies

Use of mouse anti rabies monoclonal antibodies in postexposure treatment of rabies

... Abstract Immunization of mice and hamsters with a cocktail of mouse MAbs specific for rabies virus nucleocapsid protein and glycoprotein protected animals not only when challenged with a[r] ...

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Regulation of the anti Sm autoantibody response in systemic lupus erythematosus mice by monoclonal anti Sm antibodies

Regulation of the anti Sm autoantibody response in systemic lupus erythematosus mice by monoclonal anti Sm antibodies

... developed anti-Sm positivity showed that the D specificity almost always appeared ...an anti-Sm response is initiated by D-specific B-cell clones can ...

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Molecular mimicry between the human immunodeficiency virus type 1 gp120 V3 loop and human brain proteins.

Molecular mimicry between the human immunodeficiency virus type 1 gp120 V3 loop and human brain proteins.

... Western blot immunoblot analysis of the brain proteins was performed with several monoclonal and polyclonal anti-HIV-1 antibodies including polyclonal rabbit anti-HIV-1 gp120 American Bi[r] ...

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Development and Evaluation of a Novel ELISA for Detection of Antibodies against HTLV-I Using Chimeric Peptides

Development and Evaluation of a Novel ELISA for Detection of Antibodies against HTLV-I Using Chimeric Peptides

... The antigenic activity of chimeric peptide was evaluated using 20 HTLV-I infected serum samples. According to Fig. 1, the chimeric peptide has high antigenicity and could detect all HTLV-I-infected sera. These results ...

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Thymic hyperplasia in patients with Graves' disease  Identification of thyrotropin receptors in human thymus

Thymic hyperplasia in patients with Graves' disease Identification of thyrotropin receptors in human thymus

... mouse anti–human TSH- receptor mAb (1:250; TRANSBIO, Boulogne, France), which recog- nize amino acids 604–764 of human TSH receptor (24), overnight at 4 8 C, and visualized by a biotin-streptavidin–amplified ...

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Therapeutic treatment of New Zealand mouse disease by a limited number of anti idiotypic antibodies conjugated with neocarzinostatin

Therapeutic treatment of New Zealand mouse disease by a limited number of anti idiotypic antibodies conjugated with neocarzinostatin

... of anti-Id antibodies conjugated with NCS brought about an improvement in the survival rate of female NZB/W F1 ...of anti-DNA-producing cells. The suppression of anti-DNA antibody synthesis ...

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Production and analysis of human monoclonal IgG anti-DNA antibodies

Production and analysis of human monoclonal IgG anti-DNA antibodies

... Nevertheless, anti-idiotypes generated from a human monoclonal IgG anti-DNA antibody may identify germ-line encoded ...the anti-idiotype to ...the anti-idiotypes tended to recognise IgG ...

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Antibodies against C-Reactive Protein Cross-React with 60-Kilodalton Heat Shock Proteins

Antibodies against C-Reactive Protein Cross-React with 60-Kilodalton Heat Shock Proteins

... polyclonal anti-CRP antibodies cross-react with ...of anti-CRP antibodies (Ab) with Hsp60 in solid-phase enzyme immune assays, in epitope studies using a series of overlapping synthetic ...

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Induction of a neutralizing immune response to human respiratory syncytial virus with anti-idiotypic antibodies.

Induction of a neutralizing immune response to human respiratory syncytial virus with anti-idiotypic antibodies.

... 4199 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Anti-idiotypic anti-Id antibodies were raised in rabbits against monoclonal antibodies that recognized either F gly[r] ...

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