Anti immunoglobulin e
Omalizumab, an anti-immunoglobulin E antibody: state of the art
... Abstract: A large number of trials show that the anti-immunoglobulin (Ig) E antibody omalizumab is very effective in patients with severe allergic asthma. This is acknowledged in consensus docu- ...
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Omalizumab: an anti-immunoglobulin E antibody for the treatment of allergic respiratory diseases
... OMALIZUMAB IN TREATMENT FOR ALLERGIC ASTHMA Patients with severe persistent asthma, who are poorly controlled by LABAs and ICS despite optimal compliance to treatment, are at a risk of frequent exacerbations and ...
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Exhaled Nitric Oxide in Children With Asthma Receiving Xolair (Omalizumab), a Monoclonal Anti-Immunoglobulin E Antibody
... demonstrated that omalizumab prevents the sea- sonal increase in nasal and ocular symptoms and decreases the use of rescue medication. Collectively, these studies support the concept that anti-IgE ther- apy is ...
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Treatment of Childhood Asthma With Anti-Immunoglobulin E Antibody (Omalizumab)
... Omalizumab (rhuMAb-E25) is a recombinant, human- ized, monoclonal anti-IgE antibody of mouse origin de- veloped for the treatment of IgE-mediated diseases. Omalizumab binds to free IgE at the same site as the ...
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Anti interleukin 13 and anti interleukin 4 agents versus placebo, anti interleukin 5 or anti immunoglobulin E agents, for children and adults with asthma
... The majority of anti-interleukin-13 and anti-interleukin-4 agents are humanised monoclonal antibodies (i.e. biological therapies) that bind to, and inhibit their respective inflammatory cytokines or their ...
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Asthma severity in four countries of Latin America
... test; Anti-IgE: Anti-immunoglobulin E; ASLA: Asthma control in Latin America study; ATS: American Thoracic Society; BMI: Body mass index; COPD: Chronic obstructive pulmonary disease; ER: ...
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The isotype and IgG subclass distribution of anti carbamylated protein antibodies in rheumatoid arthritis patients
... and anti-citrullinated protein antibodies (ACPAs) [5]. More recently, anti-carbamylated protein (anti-CarP) anti- bodies, which target carbamylated proteins, have been detected in RA ...of ...
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Anti T cell immunoglobulin and mucin domain 2 monoclonal antibody exacerbates collagen induced arthritis by stimulating B cells
... A previous study by Chen et al. indicated that Sema4A-Ig fusion protein does not bind to the TIM-2- transfectants [4]. Consistent with this report, we have been unable to confirm the binding of Sema4A and TIM-2 (data not ...
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Regulation and dysregulation of immunoglobulin E: a molecular and clinical perspective
... Evidence also indicates that rather than merely prim- ing mast cells to respond to specific antigen, IgE, in the absence of cross-linking agents, favorably influences mast cell survival, receptor expression, and mediator ...
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Serum immunoglobulin E and immunoglobulin G reactivity to Agaricus bisporus proteins in mushroom cultivation workers
... Background and Purpose: Although molds are regarded as the main fungal allergen sources, evidence indicates that spores of Basidiomycota including Agaricus bisporus (A. bisporus) can be also found at high concentrations ...
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ANTI-TETANUS IMMUNOGLOBULIN ISOTYPES IN WOMEN OF CHILDBEARING AGE
... and 15.38% of women with one and two injections had the highest reciprocal titers of antibody (14.96 log ) , respectively (Tables II, III). High numbers of both groups of women produced anti-tetanus antibody. ...
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Characterization of the Nuclear Localization Signal of the Borna Disease Virus Polymerase
... Fine mapping of the L-NLS was performed by fusion of L to -galactosidase in order to ensure that fusion proteins were more than 60 kDa, the threshold for passive diffusion into the FIG. 3. B-galactosidase-L fusion ...
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Mouse Polyomavirus Utilizes Recycling Endosomes for a Traffic Pathway Independent of COPI Vesicle Transport
... Only a small proportion of virions deliver their genomic DNA to the cell nucleus. At about 3 h postinfection, we could see partial colocalization of VP1 with Rab11 and transferrin, which suggests that at least a ...
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Quantitation of Immunoglobulin to Hepatitis E Virus by Enzyme Immunoassay
... Reference human antibodies. Two reference HEV antisera, designated pools 1 and 2, were prepared from serum collected from 43 (pool 1) and 35 (pool 2) donors from Nepal who were selected because a first-generation EIA ...
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The likelihood of persistent arthritis increases with the level of anti citrullinated peptide antibody and immunoglobulin M rheumatoid factor: a longitudinal study of 376 patients with very early undifferentiated arthritis
... ACPA: anti-citrullinated protein antibodies; ACR: American College of Rheuma- tology; anti-CCP: anti-citrullinated peptide antibody; anti-CCP2: 2nd genera- tion anti-citrullinated ...
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A successful birth of severe secondary recurrent miscarriage case after a decline of phosphatidylserine dependent anti prothrombin antibody by intravenous immunoglobulin administration
... Especially, while she was admitted due to uncontrolla- ble severe pregnancy-induced hypertension (PIH) hap- pened in the second pregnancy, detection of antiphos- pholipid antibodies (APA) and her past history was close ...
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Characterization of preparations enriched for Streptococcus mutans fimbriae: salivary immunoglobulin A antibodies in caries-free and caries-active subjects.
... A representative enriched S. mutans fimbria preparation was composed of 85.0% protein and 15.0% carbohydrate and had demonstrable GTF enzyme activity equal to 3.5 times back- ground that was only partially inhibitable by ...
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Subpopulations of circulating B cells and regulatory T cells involved in in vitro immunoglobulin E production in atopic patients with elevted serum immunoglobulin E
... producing immunoglobulin (Ig)E and the regulatory T cells modulating this IgE production in normals, and in atopic patients with respiratory allergy, atopic dermatitis, and markedly elevated serum IgE ...
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Performance of serological tests PGL1 and NDO LID in the diagnosis of leprosy in a reference Center in Brazil
... IgG: Immunoglobulin G; IgM: Immunoglobulin M; IPTSP/UFG: Instituto de Patologia Tropical e Saúde Pública/ Universidade Federal de Goiás; MB: Multibacillary; MDT: Multidrug therapy; ML flow: ...
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Retrospective examination of lung tissue specimens for the presence of Legionella organisms: comparison of an indirect fluorescent antibody system with direct fluorescent antibody testing
... The working dilution of the goat anti-rabbit immunoglobulin fluorescein conjugate was used to titrate each of the rabbit antisera for the various Legionella strains.. The antisera to the[r] ...
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