Anti Tubercular Therapy
The potential role of CT enterography and gastrointestinal ultrasound in the evaluation of anti-tubercular therapy response of intestinal tuberculosis: a retrospective study
... Current diagnostic and therapeutic regimens of ITB greatly rely on the evaluation of the responses to anti- tubercular therapy (ATT). Several approaches for ITB diagnosis exist, including acid-fast ...
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Effectiveness of Knowledge Based Approach for the Improvement of Patient Adherence and Reducing the Severity of Adverse Drug Reaction in Anti Tubercular Therapy
... Frederick ADK etal., 42 made a study in Ndola, Zambia, to investigate factors leading to treatment non compliance and awareness of TB transmission among patients during TB treatment, in order to propose a community-based ...
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A PHARMACOVIGILANCE STUDY IN THE DEPARTMENT OF CHEST & TUBERCULOSIS ON ANTI TUBERCULAR THERAPY IN A TERTIARY CARE TEACHING HOSPITAL OF SOUTH INDIA
... reaction does not progress to evident hepatitis and recover completely despite of the continuing INH therapy. In contrast, if clinical symptoms occur, severe Hepatocellular toxicity could be happened which is ...
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Severity Assessment and Pattern of Adverse Drug Reactions with Anti-Tubercular Therapy.
... Gastrointestinal effects were reported by 8.3% of the patients which included anorexia, nausea, vomiting, abdominal pain and diarrhea. Mild anorexia and nausea were more common (12) but were rarely severe enough to ...
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Effectiveness of real-time polymerase chain reaction assay for the detection of Mycobacterium tuberculosis in pathological samples: a systematic review and meta-analysis
... The reliability of RT-PCR to confirm an early diagnosis of TB meningitis and abdominal TB has been well estab- lished when smear and culture tests are rarely positive [89, 90]. It has also proved useful for an early ...
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Pharmacokinetics of isoniazid, rifampicin, pyrazinamide and ethambutol in Indian children
... on anti-tubercular drugs in children raises the concern of suboptimal plasma con- centrations attained when the same mg/kg dose used in adults is extrapolated to children ...of anti-tubercular ...
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Anti Tubercular Activities and Molecular Characterization of Salivary Extract of Leech (Hirudo medicinalis) against Mycobacterium tuberculosis
... [10]. Anti-tubercular therapy has been made difficult because of the increased occurrence of mul- ti-drug resistant tuberculosis (MDR-TB) and extensively drug resistant tubercu- losis ...
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Differentiation of Mycobacterium tuberculosis complex from non tubercular mycobacteria by nested multiplex PCR targeting IS6110, MTP40 and 32kD alpha antigen encoding gene fragments
... and extra-pulmonary TB which increases the sensitivity for detection [11–15]. One study has reported a robust, reproducible and uniform nested PCR (nPCR) protocol for the removal of PCR inhibitors, but nested PCR lacks ...
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Paradoxical reactions in ocular tuberculosis
... Diagnosis of this entity is often presumptive and its management lacks uniform guidelines. Establishing a prior exposure to MTB utilizing tuberculin skin tests (TST), interferon gamma release assays (IGRA), chest X- ray, ...
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Assessment of Clinical Profile, Laboratory Profile and Treatment Outcome of Tubercular Pleural Effusion treated under RNTCP daily fixed dose regimen
... diagnosed tubercular pleural effusion patients of any sex and age >18years over a period of 1year (1st Nov’17- 31st Oct’18) admitted at sri siddhartha medical college hospital and research centre, after ...
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HYDRAZIDE DERIVATIVES AND ITS BIOLOGICAL POTENTIAL-A REVIEW
... world’s current population has been infected with M.tuberculosis and new infection occurs at a rate of one per second. It is endemic in most developing countries and resurgent in developed and developing countries with ...
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IN SILICO DESIGN, SYNTHESIS AND IN VITRO ANTI TUBERCULAR AND ANTI MICROBIAL SCREENING OF NOVEL BENZIMIDAZOLE DERIVATIVES
... INTRODUCTION: The discipline of medicinal chemistry is devoted to the discovery and development of new agents for treating diseases. Most of this activity is directed to new natural or synthetic organic compounds 1 . ...
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SCREENING OF ABUTILON INDICUM L LEAF AND SEED EXTRACTS FOR ANTITUBERCULAR ACTIVITY
... Anti tubercular Activity screening Antitubercular activity of all solvent extracts was tested against the Mycobacterium tuberculosis H37Ra and Mycobacterium bovis strains using the micro[r] ...
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SYNTHESIS OF SOME NOVEL FORMAZANS AS POTENTIAL ANTITUBERCULAR AGENTS
... The selected compounds were screened for their anti-tubercular activity by microplatealamar blue assay (MABA) method. The effectof the synthesized compounds were tested with different concentrations ...
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“In Vitro Hepatoprotective Activity of Barleria montana Nees Leaves against Anti-Tubercular Drugs induced Hepatotoxicity in BRL3A Cell Lines” by Jyothi Basini, Mohana Lakshmi Sabapathi, India.
... of anti-tubercular drugs (HTS2) elevates the formation of lipid peroxides and ROS, leading to the inactivation of enzymatic and non-enzymatic antioxidants in the ...by anti- tubercular drugs ...
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Drug resistance profile among multi-drug resistant tuberculosis patients at diagnosis and correlation with history of anti-tubercular treatment in a tertiary care center
... Many of the factors mentioned does not hold true for patients because most had received appropriate therapy, most had adhered to treatment, none had contact with DR-TB cases and none had received SLD (except FQ). ...
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Identification of the anti mycobacterial functional properties of piperidinol derivatives
... Treatment of TB is increasingly hindered by the emergence of drug-resistant strains and this has led to increased efforts in the identification of new potent inhibitors of M. tuberculosis and pharmacologically validated ...
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Rare Case of Multifocal Cutaneous Tuberculosis Verrucosa Cutis: Posing Clinical and Histopathological Diagnostic Dilemma
... Tuberculosis verrucosa cutis (TBVC) occupies a pre-eminent position across the spectrum of cutaneous tuberculosis. TBVC is positioned between lupus vulgaris and scrofuloderma. TBVC is no longer the most frequent type of ...
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A Study on Assessment of Adverse Drug Reactions in Patients with Tuberculosis in a Tertiary Care Teaching Hospital
... with Anti-tubercular drugs can result in non-compliance and therapeutic ...by anti-tubercular drugs and their assessment by using causality, severity and preventability ...
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Non antibiotic therapy for mycobacterium tuberculosis infection
... of therapy, marked drug toxicity, failure of the patient to complete the prescribed ...possess anti tubercular activity are -1] Phenothiazines like Chlorpromazine and Thioridazine 2] proton pump ...
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