antibody-mediated rejection
Original Article Acute cellular rejection and antibody-mediated rejection in endomyocardial biopsy after heart transplantation: a retrospective study from a single medical center
... Phosphorylated S6 kinase (S6RP) and 70 S6-kinase (S6K) protein immunostainings were performed in patients with histological or clini- cal suspicion of antibody-mediated rejection. The patients with ...
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Eculizumab to Treat Antibody-Mediated Rejection in a 7-Year-Old Kidney Transplant Recipient
... Humoral sensitization to HLA antigens as a result of a previous transplant, pregnancy, or blood transfusions has emerged in recent years as one of the most challenging clinical problems in kidney transplantation. ...
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Clazakizumab in late antibody mediated rejection: study protocol of a randomized controlled pilot trial
... Late antibody-mediated rejection (ABMR) triggered by donor-specific antibodies (DSA) is a cardinal cause of kidney allograft dysfunction and ...this rejection type are well established, but ...
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Current perspectives on antibody-mediated rejection after lung transplantation
... of antibody-mediated rejection (AMR) in lung transplantation remain ...cellular rejection and ...of rejection and conduct clinical trials to identify optimal treatment ...
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Treatment of acute antibody-mediated rejection using Rituximab
... Acute rejection (AR) is one of its complications that are associated with a high frequency of graft loss in some cases or graft dysfunction in others (1, ...Acute Antibody Mediated Rejection ...
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Eculizumab to Treat Antibody-Mediated Rejection in a 7-Year-Old Kidney Transplant Recipient
... Humoral sensitization to HLA antigens as a result of a previous transplant, pregnancy, or blood transfusions has emerged in recent years as one of the most challenging clinical problems in kidney transplantation. ...
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Antibody mediated rejection across solid organ transplants: manifestations, mechanisms, and therapies
... of antibody-mediated rejection (AMR), and our knowledge of the mechanisms of antibody-medi- ated allograft injury have expanded our understanding of ...
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Rituximab, plasma exchange and immunoglobulins: an ineffective treatment for chronic active antibody-mediated rejection
... active antibody-mediated rejection; CCI: Charlson comorbidity index; DSA: Donor specific antibodies; eGFR: Estimated glomerular filtrated rate; IFTA: Interstitial fibrosis and tubular atrophy; IVIG: ...
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Treatment with intravenous immunoglobulins and methylprednisolone may significantly decrease loss of renal function in chronic-active antibody-mediated rejection
... Chronic-active Antibody Mediated Rejection (c-aABMR) is an important cause of renal allograft dysfunction over time, often presenting as a continuous decline in allograft function, either with or ...
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Late antibody-mediated rejection after ABO-incompatible kidney transplantation during Gram-negative sepsis
... details). Antibody titer changes were investigated as well: after centrifugation the supernatant was stored at 4°C and anti-A titers were measured the following day by adding A erythrocytes in serial plasma ...
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The Effect of Bortezomib on Antibody Mediated Rejection after Kidney Transplantation
... Histologic data are shown in Table 2. All rejection episodes manifested as pure AMR, that is, not as AMR mixed with acute cellular rejection. C4d status and biopsy scoring are presented according to the ...
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Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody mediated rejection
... a sufficient amount of Ab from the circulation to the site of tissue damage has been a driving evolutionary force for lymphoid neo- genesis: the process by which ectopic “tertiary lymphoid organs” appear within ...
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Bortezomib in late antibody mediated kidney transplant rejection (BORTEJECT Study): study protocol for a randomized controlled trial
... Background: Despite major advances in transplant medicine, improvements in long-term kidney allograft survival have not been commensurate with those observed shortly after transplantation. The formation of donor-specific ...
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Delayed hyperacute rejection in a patient who developed <em>clostridium difficile</em> infection after ABO-incompatible kidney transplantation
... The patient had good initial graft function with creatinine decreasing to 1.7 mg/dL on POD#6. Nonetheless, plasma- pheresis was performed on POD#6 for an anti-A1 IgG titer of 1:32 per our protocol. On POD#7, however, his ...
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Expression of MMP-2 and TIMP-1 in Renal Tissue of Patients with Chronic Active Antibody-mediated Renal Graft Rejection
... humoral rejection and was included in Banff 07 pathologic diagnostic criteria, there- fore chronic active antibody-mediated rejection (AMR) was being paid more and more attention ...
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Bronchus associated lymphoid tissue–resident Foxp3+ T lymphocytes prevent antibody mediated lung rejection
... Antibody-mediated rejection (AMR) is a principal cause of acute and chronic failure of lung ...in rejection-free human lung grafts and accumulated within induced bronchus-associated lymphoid ...
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Myocardial T1 mapping: where are we now and where are we going?
... Cardiac magnetic resonance T1 mapping pre and post contrast in heart transplant patients with clinical antibody-mediated rejection: a preliminary experience. Edwards NC, Moody W[r] ...
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Longitudinal immunological characterization of the first presensitized recipient of a face transplant
... for antibody-mediated rejection (AMR) following face transplantation have been ...cell–mediated rejection (TCMR), there is a critical need to delineate the features that can ...
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Rituximab: An emerging therapeutic agent for kidney transplantation
... and antibody responses in solid-organ transplant ...of antibody-mediated rejection (AMR), post-transplant lymphoproliferative disorder (PTLD), and recurrent glomerular diseases in the renal ...
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Neuropsychiatric Lupus with Antibody Mediated Striatal Encephalitis
... A 38-year-old man presented with progressively worsening cog- nitive impairment, orofacial dyskinesia, and bilateral upper ex- tremity chorea. MR imaging of the brain demonstrated bilateral symmetric T2/FLAIR ...
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