Antifungal therapy
Fluconazole for empiric antifungal therapy in cancer patients with fever and neutropenia
... empiric therapy, the treatment failure for these patients might be due to a low dose of fluconazole (6 patients on daily dose of 200 mg and 1 patient on 600 mg) while other trials on empiric fluconazole ...
10
Combination Antifungal Therapy for Cryptococcal Meningitis
... received antifungal therapy for more than 3 days, had had cryptococcosis, were pregnant, had renal or liver failure, were receiving rifampin, or did not provide written informed ...
12
Antifungal Therapy in Children With Invasive Fungal Infections: A Systematic Review
... additional antifungal therapy) was observed in 51% of children who received CAB, 64% who received 1 mg/kg per day of liposomal amphotericin B, and 63% who received 3 mg/kg per day of liposomal amphotericin ...
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Impact of inappropriate antifungal therapy according to current susceptibility breakpoints on Candida bloodstream infection mortality, a retrospective analysis
... combination therapy with AmB-d and fluconazole, and one received ...initial antifungal agent was modified in 37% (55/149) of the ...other antifungal due lack of a clinical response; ...tive ...
9
EVALUATION OF APPROPRIATE USE OF ANTIFUNGAL THERAPY IN A TERTIARY CARE HOSPITAL
... of antifungal used in Malays compared to other ...affect antifungal outcome, appropriate antifungal therapy was assessed based on four criterias: Indication, appropriate dosage, drug-drug ...
5
Development of fluconazole resistance in a series of Candida parapsilosis isolates from a persistent candidemia patient with prolonged antifungal therapy
... An 82 year-old male was admitted to the PUMCH in December, 2008 with severe, acute pancreatitis. He was managed with mechanical ventilation and received par- enteral nutrition, diuretics and anti-microbial ...
7
Clinical characteristics and outcomes in 303 HIV-infected patients with invasive fungal infections: data from the Prospective Antifungal Therapy Alliance registry, a multicenter, observational study
... Data for each IFI were collected, including patient demographics and clinical characteristics, comorbidities, existing medications and antifungal therapies, immunologic risk, and concomitant bacterial and viral ...
9
Mitochondria and Fungal Pathogenesis: Drug Tolerance, Virulence, and Potential for Antifungal Therapy
... of antifungal drugs and for virulence, our understanding of the roles of this organelle in human fungal pathogens is still ...of antifungal drugs, but the exact molecular mechanisms are not fully ...
8
Assessment of Antifungal Therapy in an 800-Gram Infant with Candidal Arthritis and Osteomyelitis
... Pharmacologic properties and toxicities of antifungal drugs, however, have not been defmed for the neonate or young infant; hence, we report the successful treatment of a low-birth-weigh[r] ...
7
New Formulation Strategies in Topical Antifungal Therapy
... Different type of topical delivery systems of flucona- zole, including emulsion, emulgel, lipogel, and thickened microemulsion-based hydrogel have been evaluated to optimize the formulation type based on its drug ...
10
Serum galactomannan index for early prediction of mortality in immunocompromised children with invasive pulmonary aspergillosis
... were risk factors for mortality in a univariate analysis in the present study. However, none of them were signifi- cantly associated with mortality in a multivariate ana- lysis. Although the duration of fever and ...
10
Diagnostic Issues, Clinical Characteristics, and Outcomes for Patients with Fungemia
... corticosteroid therapy, or mechanical ventilation or had undergone ...or antifungal therapy given in the 2 weeks before blood culture, the therapy given for the present episode of fungemia, ...
9
MANAGEMENT OF FEBRILE NEURTROPENIA IN ONCOLOGY PRACTICE
... combination therapy using ...Empirical antifungal therapy should be added after 4 days of persistent fever in patients at high risk for invasive fungal infection (IFI); the details of the ...
6
Epidemiology, species distribution and outcome of nosocomial Candida spp bloodstream infection in Shanghai
... tifungal therapy and mortality was demonstrated ...of antifungal treatment 48 h after having the first positive blood culture report was an independent determinant of hospital ...empirical antifungal ...
10
(1,3) β D glucan based diagnosis of invasive Candida infection versus culture based diagnosis in patients with sepsis and with an increased risk of invasive Candida infection (CandiSep): study protocol for a randomized controlled trial
... the antifungal therapy is de- layed until there is microbiological proof of fungal infec- tion ...early antifungal therapy triggered by BDG serum concentration will reduce ICI occurrence to ...
10
Successful management of cryptococcosis of the bilateral adrenal glands and liver by unilateral adrenalectomy with antifungal agents: a case report
... to antifungal chemotherapy ...case, antifungal therapy was effective in reducing the liver mass, but the bilateral adrenal masses did not change and the liver mass still ...
5
Severe mycosis as a rare infection after a corn auger injury of the hand: a case report
... Even with surgery, these infections are so serious and difficult to manage that death may ultimately occur. Kontogiori et al. describe a fatal case of necrotizing fas- ciitis in a 25-year-old, previously healthy farmer ...
5
A Study on the Prevalence of Oropharyngeal Candidiasis in the Immunocompromised Individuals and their Antifungal Susceptibility Pattern in Tirunelveli Medical College Hospital.
... Systemic antifungal chemotherapy can be associated with toxicity, cost, and emergence of ...pre-emptive antifungal therapy, which consists of limiting antifungal therapy only to those ...
121
A systematic review of the impact of antifungal stewardship interventions in the United States
... Establishing the impact of AFS interventions on clinical outcomes should be a primary focus along with reporting antifungal utilization and other process outcomes. Only a few studies evaluated clinical outcomes ...
10
Aspergillosis in Intensive Care Unit (ICU) patients: epidemiology and economic outcomes
... initial antifungal therapy: a one day delay in starting anti- aspergillus antifungal therapy was associated with ap- proximately ...initial antifungal therapy also had a ...
8