anulus fibrosus
Fabrication and properties of acellular porcine anulus fibrosus for tissue engineering in spine surgery
... Keywords: Anulus fibrosus, Decellularization, Acellular, Disc degeneration, Intervertebral disc, Tissue engineering.. Introduction.[r] ...
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Brückner, Stella (2004): Histo- und cytochemische Untersuchung der Zwischenwirbelscheibe des Rhesusaffen (Macaca mulatta). Dissertation, LMU München: Medizinische Fakultät
... des Anulus fibrosus können in den Gallertkern einbezogen werden (BRETTSCHNEIDER, ...des Anulus fibrosus sind in den Randleisten der Wirbelkörper verankert, weiter innen strahlen sie ...
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The Human Inter Vertebral Disc - A Histological Approach
... collagenous anulus fibrosus laterally and the cartilage end plates inferiorly and ...The anulus consists of concentric rings or lamellae, with fibers in the outer lamellae continuing into the ...
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Potential use of human adipose mesenchymal stromal cells for intervertebral disc regeneration: a preliminary study on biglycan deficient murine model of chronic disc degeneration
... AF: anulus fibrosus; Bgn −/0 : biglycan-deficient mice; DAPI: 4',6-diamidino-2-phenylindole; DMEM: Dulbecco's modified Eagle's medium; D-PBS: Dulbecco ’ s phosphate-buffered saline; ECM: extracellular ...
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Effect of autologous platelet rich plasma releasate on intervertebral disc degeneration in the rabbit anular puncture model: a preclinical study
... Abbreviations AF: anulus fibrosus; ANOVA: analysis of variance; BMP: bone morphogenetic protein; DHI: disc height index; EGF: epidermal growth factor; GDF-5: growth differentiation facto[r] ...
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The Anatomic Basis of Vertebrogenic Pain and the Autonomic Syndrome Associated with Lumbar Disk Extrusion
... 12.-Schematic diagram of innervation of anterior spinal canal and structures of anterior aspect of spinal column modified from [15-17]: 1 = nucleus pulposus; 2 = anulus fibrosus; 3 = ant[r] ...
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RANK/RANKL/OPG system in the intervertebral disc
... AF: Anulus fibrosus; ANOVA: Analysis of variance; CEP: Cartilaginous endplate; FBS: Fetal bovine serum; Fisher PLSD test: Fisher protected least significant difference test; HE: Hematoxylin and eosin; HRP: ...
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The Value of T2 Relaxation Times to Characterize Lumbar Intervertebral Disks: Preliminary Results
... The current strategy used to quantify disk degeneration by MR is the use of morphologic criteria. 1,2 Specific findings such as clefts in the annulus fibrosus, decreased signal intensity, and loss of height are ...
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Tissue discrimination by bioelectrical impedance during PLL resection in anterior decompression surgery for treatment of cervical spondylotic myelopathy
... (annulus fibrosus, endplate cartilage, sub-endplate cortical bone, and PLL; PLL, dura mater, spinal cord, and nerve root) using a novel probe and a precision inductance-capacitance-resistance ...
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Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells
... Abbreviations ADAMTSs: A distintegrin and metalloproteinase with thrombospondin motifs; AF: Annulus fibrosus; B: basal; C: Chondrogenic; CTGF: connective tissue growth factor; CM: condit[r] ...
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Standardisation of basal medium for reproducible culture of human annulus fibrosus and nucleus pulposus cells
... The lifetime prevalence of degenerative disc disease (DDD) is very high. Over 90% of over age 50 show radiographic signs of DDD in magnetic resonance imaging studies [1]. Degeneration of the intervertebral disc (IVD) is ...
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Mild (not severe) disc degeneration is implicated in the progression of bilateral L5 spondylolysis to spondylolisthesis
... Annulus Fibrosus; ALL: Anterior Longitudinal Ligament; CL: Capsular Ligament; CT: Computed Tomography; DICOM: Digital Imaging and Communications in Medicine; DOF: Degrees of Freedom; Ex: Extension; FE: Finite ...
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Integrating Theoretical and Experimental Methods for Multi-Scale Tissue Engineering of the Annulus Fibrosus of the Intervertebral Disc
... annulus fibrosus is predicated on a high degree of structural organization over multiple length scales: aligned bundles of collagen fibers reside within each lamella and the direction of alignment alternates from ...
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Osteogenic differentiation of bone marrow stromal cells is hindered by the presence of intervertebral disc cells
... The NP is derived from the notochord of mesodermal origin [5]. During development, the notochord in the human embryo gradually breaks down and is enclosed within the primitive annulus fibrosus (AF) that later ...
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Expression of silent mating type information regulator 2 homolog 1 and its role in human intervertebral disc cell homeostasis
... Abbreviations AF: annulus fibrosus; BSA: bovine serum albumin; DMEM: Dulbecco’s modified Eagle’s medium; GAPDH: glyceraldehyde 3-phosphate dehydrogenase; IL: interleukin; IVD: interverte[r] ...
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MMP 2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc
... By using RNAi, we showed that MMP-2 functions as the primary gelatinase and is used by AF cells for degrading the local surrounding matrix.. Notably, in the absence of MMP-2, collagen re[r] ...
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Intervertebral Disk Appearance Correlated withStiffness of Lumbar Spinal Motion Segments
... in the annulus fibrosus probably explain the high degree of stiffness we found with normal interver- tebral disks that had an intact annular fibrosus (16). We did not attempt to correlate the amount of ro- ...
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TGF-β1 reduces the oxidative stress-induced autophagy and apoptosis in rat annulus fibrosus cells through the ERK signaling pathway
... Intervertebral disc degeneration: the role of the mitochondrial pathway in annulus fibrosus cell apoptosis induced by overload. Beta1 integrin inhibits apoptosis induced by cyclic stretc[r] ...
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The biology behind the human intervertebral disc and its endplates
... The two different parts of the IVD — the AF and the NP arise on two separate developmental pathways. At approximately 30 days human foetal gestation cells of the sclerotome migrate medially from pairs of paraxial somites ...
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Orbital Apex: Correlative Anatomic and CT Study
... Passing through the anulus of Zinn via the optic canal are the optic nerve and ophthalmic artery and via the superior orbital fissure are cranial nerves III superior and inferior branche[r] ...
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