atherosclerotic plaque
Carotid Atherosclerotic Plaque Progression and Change in Plaque Composition Over Time: A 5 Year Follow Up Study Using Serial CT Angiography
... investigate atherosclerotic carotid plaque progression in hu- ...quantify atherosclerotic plaque measures in vivo and track changes over time in large study ...in plaque volume was ...
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Intracranial Atherosclerotic Plaque Enhancement in Patients with Ischemic Stroke
... with atherosclerotic plaque(s) in the ves- sel(s) supplying the territory of ...had plaque, with 1 showing mild enhancement and the other no ...
6
Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR −/− mouse model of atherosclerosis
... attenuate plaque formation, we used the LDLR -/- mouse model of atherosclerosis ...reverse atherosclerotic plaque formation in mice fed a high-fat (HFD) diet (or chow as ...
36
Aldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaque
... is atherosclerotic plaque disruption, which may result from increased plaque vulnerability ...[29]. Plaque vulnerable to disruption is characterized by increased content of lipids and ...
15
Berberine derivatives reduce atherosclerotic plaque size and vulnerability in apoE−/− mice
... aortic atherosclerotic le- sion size, improved plaque stability (increased α-SMA and collagen content, and increased fibrous cap thickness), and decreased EMMPRIN, MMP-9, CD68, ICAM-1, VCAM-1 and NFκB p65 ...
13
Reproducibility of 3-dimensional ultrasound readings of volume of carotid atherosclerotic plaque
... [6]. Atherosclerotic plaque volume assessed by 3-dimensional (3D) US [7] may represent a more reliable measure of atherosclerosis than IMT [8] and more recently non-invasive 3D US imaging has ermerged as ...
8
Ultrasound imaging versus morphopathology in cardiovascular diseases. Coronary atherosclerotic plaque
... Different echocardiographic techniques have been employed in the attempt to provide adequate visualiza- tion of coronary arteries (Table 2). However, intracoro- nary ultrasound (ICUS) represents the most valuable method ...
10
Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation
... In this study, we examined lipid peroxidation products, ie, thiobarbituric acid reactive substances (TBARS) and LDL-conjugated diene, formed as a result of oxidative stress generated in a hypercholesterolemic ...
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Identification and Quantitative Assessment of Different Components of Intracranial Atherosclerotic Plaque by Ex Vivo 3T High Resolution Multicontrast MRI
... Intracranial atherosclerosis is increasingly recognized as an important cause of stroke worldwide. As with carotid atheroscle- rosis, there is increasing recognition that aggressive (dual) antiplatelet therapy may be ...
7
Statins Induce the Accumulation of Regulatory T Cells in Atherosclerotic Plaque
... Tregs secrete two major cytokines (TGF- β and IL-10), which are associated with their survival and function (30). TGF- β plays an important role in regulat- ing the signaling pathway that promotes Foxp3 expression and ...
8
Developing a novel rabbit model of atherosclerotic plaque rupture and thrombosis by cold-induced endothelial injury
... Because atherosclerotic plaque rupture occurs in a ran- dom fashion, by its very nature it is difficult to study directly in ...prevent plaque rupture and thrombosis from happening on a large ...
9
Original Article Cystatin C is associated with coronary artery disease and coronary atherosclerotic plaque morphology in patients with normal glomerular filtration rate
... atherosclerosis, plaque rupture, restenosis, and aneurysm ...of atherosclerotic plaque and ab- dominal aortic aneurysm (AAA) were decreased and the cathepsin was ...
9
In silico analyses of metagenomes from human atherosclerotic plaque samples
... and atherosclerotic plaque microbiotas [5, 15, ...the plaque in patients with advanced athero- sclerotic disease ...symptomatic atherosclerotic plague samples (average ...stable plaque ...
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Mathematical modelling of the atherosclerotic plaque formation
... This work is motivated by the design of mathematical models and numerical tools to simulate the first steps in the atherosclerotic plaque formation. The main goal is first to build a mathematical model of ...
12
3D Quantitative Evaluation of Atherosclerotic Plaque Based on Rotational Angiography
... ticular, atherosclerotic plaque has been associated with many acute clinical ...icant atherosclerotic narrowing at the origin of the internal carotid ...
6
Sex Differences of High Risk Carotid Atherosclerotic Plaque with Less Than 50% Stenosis in Asymptomatic Patients: An In Vivo 3T MRI Study
... carotid plaque and the presence of a thin or ruptured fibrous cap and IPH and the size of LR/NC in patients with ⬍50% ...of atherosclerotic plaque exists even during the early stages of the disease ...
7
Ticagrelor promotes atherosclerotic plaque stability in a mouse model of advanced atherosclerosis
... rotic lesion evaluation is a standard method, next to lesion evaluation “en-face” or within the innominate artery. As a limitation, we cannot exclude that site-specific effects can bias our data. To explore the potential ...
9
CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis
... Human plaque histology. The specimens used in the PIT versus TCFA coronary plaque study (65% men, age 71.7 ± 12.4 years) were obtained at autopsy. Specimens were formalin fixed, paraffin embed- ded, and ...
16
Shear stress–induced changes in atherosclerotic plaque composition are modulated by chemokines
... addition, the lesions contained increased amounts of extracellular matrix (collagen) and VSMCs, thereby increasing collagen synthe- sis, when compared with the lesions of the control group. Impor- tantly, inhibition of ...
12
High resolution intravascular magnetic resonance quantification of atherosclerotic plaque at 3T
... identify atherosclerotic lesions, followed by high-resolution CMR to characterize FCT, lesion size, and/or vessel wall ...and plaque size in healthy and hyperlipidemic rabbit models, with post-mortem ...
11