autoimmune premature ovarian failure
Ovarian antibodies as detected by indirect immunofluorescence are unreliable in the diagnosis of autoimmune premature ovarian failure: a controlled evaluation
... has ovarian failure on an au- toimmune ...diagnose autoimmune oophoritis with certainty ...commercial ovarian antibody tests for the diagnosis of au- toimmune premature ovarian ...
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EXPLORATION OF ANTI OVARIAN ANTIBODIES IN FEMALES UNDERGOING INTRAUTERINE INSEMINATION AND IN VITRO FERTILIZATION; A PRELIMINARY STUDY
... 2003). Autoimmune premature ovarian failure (POF) has been considered to be a mechanism possibly responsible for primary idiopathic ...and ovarian antibodies i.e. ovarian ...
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Treatment of Premature Ovarian Failure by Ultrasound Intra Ovarian Injection of Bee Venom
... Primary ovarian insufficiency (POI) or premature ovarian failure (POF) or premature menopause is defined as cessation of menstruation before the expected age of Menopause (40 years) ...
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ANTI FOLLICLE STIMULATING HORMONE ANTIBODIES IN POLYCYSTIC OVARY SYNDROME AND APPEARANTLY HEALTHY CONTROLS
... in autoimmune pathology, detection of specific autoantibodies seems to be the most practical clinical and research marker of most autoimmune ...ensuing ovarian dysfunction often results in ...
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Molecular cytogenetic analysis of Xq critical regions in premature ovarian failure
... 30 years of age the incidence was 1:1000 [1]. In addition to a reduction in the duration of fertility, there are other important health issues that may be associated with POF such as an increased risk of overall ...
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Premature ovarian failure
... The causes of POF are extremely heterogeneous. Acquired forms such as those occurring after treatments for neo- plastic diseases or autoimmune diseases account for many cases [1]. POF has a strong genetic ...
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Down-regulation of progesterone receptor membrane component 1 (PGRMC1) in peripheral nucleated blood cells associated with premature ovarian failure (POF) and polycystic ovary syndrome (PCOS)
... part of a membrane complex that binds progesterone [2,3]. PGRMC1 is believed to be involved in progesterone signaling in the reproductive system and it mediates pro- gesterone's anti-apoptotic effects on granulosa cells ...
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Short stature and primary ovarian insufficiency possibly due to chromosomal position effect in a balanced X;1 translocation
... The other gene we found overexpressed in the pro- band, the DIAPH2 gene [14], affects fertility in female flies, and has been found disrupted in a family with POI, though no mutation demonstrated its role in ...
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Reproductive issues in patients undergoing Hematopoietic Stem Cell Transplantation: an update
... with ovarian stimulation) and pelvic infections should be included in the ...and ovarian size should be performed in each ...age, ovarian reserve should be evaluated including Antral Follicular Count ...
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Oral Cyclophosphamide Confounds the Relationship between CYP2C19 and CYP2B6 Pharmacogenetics and Cyclophosphamide induced premature Ovarian Failure in Lupus Nephritis Patients
... Figure 1. Hepatic activation of the prodrug cyclophosphamide to the DNA cross linking product phosphoramide mustard which is responsible for cytotoxicity to proliferating cells including ovarian follicle granulosa ...
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Identification of X chromosome genes causing premature ovarian failure
... only ovarian function while those of the short arm affect stature as well (Sarto et al 1973, Therman et al ...specific ovarian function genes are disrupted at a breakpoint, rather than a general ...
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Investigating the role of X chromosome breakpoints in premature ovarian failure
... Banding cytogenetic techniques, such as QFQ (Q-bands by Fluorescence using Quinacrin), GTG (Giemsa-Trypsin- Giemsa) and RHG (R-bands by heating using Giemsa) banding, showed the presence of abnormal karyotypes in 4 ...
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ESR1, HK3 and BRSK1 gene variants are associated with both age at natural menopause and premature ovarian failure
... (mean age 23.85 ± 6.78 years) (Table 1). 8% (32/400) of cases had a positive family history, i.e., at least two first- or second-degree female family members with POF or early menopause including the index POF patient. ...
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Investigation of KIT gene mutations in women with 46,XX spontaneous premature ovarian failure
... The SSCP technique has been used successfully for muta- tion searching in other genes. [23–26] Using the PCR- SSCP technique we were able to detect only one polymor- phism in the entire coding regions of the KIT gene, ...
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Beneficial Effects of Tibolone on Sexual Dys function in Women with Premature Ovarian Failure (POF)
... 2 Factors that could contribute to sexual dysfunction and, 3 The effect of hormone replacement therapy using Tibolone among women with premature ovarian failure in Kuwait... Patients and[r] ...
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THE ROLE OF GENE THERAPY IN PREMATURE OVARIAN INSUFFICIENCY MANAGEMENT
... Premature ovarian insufficiency (POI) affects 1% of women by 40 years of age and less than ...defects, autoimmune and enzymatic disorders are among the known ...
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Human chorionic plate-derived mesenchymal stem cells transplantation restores ovarian function in a chemotherapy-induced mouse model of premature ovarian failure
... been used to recover the ovarian function damaged by chemotherapy and have shown a therapeutic prospect for POI [8–13]. Human placenta-derived MSCs (pdMSCs) were considered as good sources of MSCs for various ...
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Chromosome territories, X;Y translocation and Premature Ovarian Failure: is there a relationship?
... Family history was negative for birth defects, mental retar- dation, congenital malformations, or consanguinity. Preg- nancy history was normal and at birth the patient had no dysmorphic features. At the age of 10 she ...
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Emotional Impacts of Premature Ovarian Failure in Kuwait
... Premature Ovarian Failure (POF) is cessation of ovarian functions before the age of 40 years with consequent cessation of ...have Premature Ovarian Failure seen at the ...
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Fetal liver mesenchymal stem cells restore ovarian function in premature ovarian insufficiency by targeting MT1
... POI ovarian granule cells recovered ovarian function by pro- moting the proliferation rate and inhibiting the apop- tosis ...rescue ovarian function ...
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