Autoimmune type 1 diabetes
Higher cardiometabolic risk in idiopathic versus autoimmune type 1 diabetes: a retrospective analysis
... This pilot study was approved by the Institutional Review Board at the Faculty of Medicine of the University of Palermo. At the time of observation all patients regularly signed an informed consent for the scientific use ...
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Autoimmune type 1 diabetes: resolved and unresolved issues
... human type 1 diabetes comes largely from random autopsy specimens obtained from patients who died either near the time of diagnosis from acute metabolic diabetic ketoacidosis or late in the course of ...
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CD122 blockade restores immunological tolerance in autoimmune type 1 diabetes via multiple mechanisms
... Type 1 diabetes (T1D) is a prototypical autoimmune disease, characterized by specific destruction of insulin-pro- ducing β cells by a mistakenly activated self-immune system (1, ...
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Pernicious Anemia Associated Autoimmune Diseases in a Sub Saharian African Internal Medicine Service
... an autoimmune disease. It is characterized by the presence of an autoimmune atrophic gastritis and various autoantibodies that lead to a vitamin B12 deficiency responsible for a macrocytic ...with ...
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Helicobacter pylori infection might be responsible for the interconnection between type 1 diabetes and autoimmune thyroiditis
... years; diabetes duration: 7.29 ± 7.9) attending out- patient diabetes clinics at Pediatric and Specialized Med- ical Hospitals, Mansoura University, Egypt were studied (Table ...American Diabetes ...
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Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes
... Both islet cell death and Fas expression are enhanced in NOD compared to Idd9 islets following exposure to the inflammatory cytokines TNF and IFNγ in vitro, suggesting that NOD β cells are hyper-responsive to these ...
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High frequency of vitamin D receptor gene polymorphism FokI in Brazilian Type 1 diabetes mellitus patients with clinical autoimmune thyroid disease
... The susceptibility genes for T1DM and AITD identified to date, HLA class II, CTLA-4, PTNP22 and FOXP3 are involved in the immunological synapse and T cell acti- vation [8, 34]. Van Etten et al. [25] had studied in vitro ...
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Clinical, Autoimmune, and HLA Characteristics of Children Diagnosed With Type 1 Diabetes Before 5 Years of Age
... with type 1 diabetes before 5 years of age at the pediatric diabetes center of Loma Linda University Children’s Hospital, from 1995 to ...of type 1 dia- betes was based on ...
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Type 1 autoimmune pancreatitis
... Type 1 AIP predominantly affects adult males with > 90% of patients being more than 40 years of ...be type 1 AIP by histological examination ...of type 1 AIP patients is ...
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The interpretation and management of thyroid disorders
... with type 1 diabetes and a history or symptoms of thyroid dysfunction, and with lithium or amiodarone therapy to evaluate the risk of developing autoimmune thyroid ...
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Abstract
... in type 1 ...and diabetes, autoimmune thyroid disease, and rheumatoid ...concerning type 1 diabetes in Lithuanian, Finnish, British, Nor− wegian, and American Caucasian ...
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Ketosis-prone diabetes and SLE co-presenting in an African lady with previous gestational diabetes
... ketosis-prone diabetes with diabetes-associated autoantibodies, after being admitted for diabetic ketoacidosis (DKA) precipitated by her first presentation of systemic lupus erythematosus ...gestational ...
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Cytotoxic T lymphocyte antigen 4 +49A/G polymorphisms in Sudanese adults with type 1 diabetes and latent autoimmune diabetes
... A case–control study was conducted in Gadarif Teach- ing Hospital clinic in the eastern Sudan during the period of February through August 2017. The cases (were part of the patient who had the initial clinical diagno- ...
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Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes
... Since BMDCS consists of European-descent children ascertained from the USA, while the LADA cases were adults ascertained from the UK and Germany, we also leveraged 2820 healthy adult British birth cohort con- trols from ...
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Metabolic Syndrome in Type 1 Diabetes
... Type 1 diabetes mellitus (DM1) is due to the autoimmune destruction of beta cells within the pancreatic ...an autoimmune cause, the underlying defect that causes type 2 ...
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“Birds of a Feather Flock Together”: Type 1A Diabetes and Other Autoimmune Disease States
... C.S. is a 17-year-old girl who has had type 1 diabetes for 14 years. During early childhood, her hemoglobin A 1c (A1C) was usually < 8%, and her mother performed most of her dia- betes care tasks. ...
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Cutaneous vasculitis in patients with autoimmune polyendocrine syndrome type 1: report of a case and brief review of the literature
... hypothyroidism, type 1 diabetes, gastro- intestinal dysfunction, autoimmune hepatitis, asplenia and various ectodermal abnormalities (interstitial keratitis, alo- pecia, vitiligo, nail ...
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Postprandial Cardiometabolic risk in Autoimmune Thyroid Disease and Type 1 Diabetes Mellitus
... accordingly, diabetes is broadly classified based on its ...mediated autoimmune destruction of the insulin secreting β-cells of the islets of Langerhans in the pancreas, leading to insulin ...other ...
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Association of insulin gene VNTR INS -23/Hph1 A>T (rs689) polymorphism with type 1 diabetes mellitus in Egyptian children
... A mechanistic explanation of the association has been proposed, as the A T1DM-risk allele, suggested in some studies, is claimed to relate to lower levels of insulin tran- scription in thymus leading to non-effective ...
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Preclinical carotid atherosclerosis in patients with latent autoimmune diabetes in adults (LADA), type 2 diabetes and classical type 1 diabetes
... the type of diabetes the crude Odds Ratio was calculated and sub- sequently adjusted with the respective confidence inter- vals at ...the type of diabetes, were duration of diabetes, ...
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