Baculovirus infection
Baculovirus Infection Induces a DNA Damage Response That Is Required for Efficient Viral Replication
... by baculovirus infection, suggesting a possible relationship between baculoviruses and the DNA damage ...the baculovirus Autographa californica M nucleopoly- hedrovirus (AcMNPV) in the cell line Sf9, ...
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In Vivo Induction of Apoptosis Correlating with Reduced Infectivity during Baculovirus Infection
... the infection, strong-phenotype caterpillars showed a pattern of increasing eGFP expression in the peripheral, and to a lesser extent the perivisceral, fat body coupled with very large reduction in fat body ...
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Downregulation of a Chitin Deacetylase-Like Protein in Response to Baculovirus Infection and Its Application for Improving Baculovirus Infectivity
... to baculovirus infection as a protective mechanism was supported by the increase in virulence and pathogenicity of HaCDA5a-expressing virus in comparison to the parental ...after infection ...
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Persistent Baculovirus Infection Results from Deletion of the Apoptotic Suppressor Gene p35
... persistent baculovirus infection can be used as an efficient protein ex- pression system, continuous protein expression using persis- tent viral infection may have several advantages over stable ...
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Effects of baculovirus infection on IE1-mediated foreign gene expression in stably transformed insect cells.
... IEl-mediated expression of the integrated genes in transformed insect cells is likely to be blocked at the transcriptional level at late times of baculovirus infection, when the foreign [r] ...
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Baculovirus Infection of Nondividing Mammalian Cells: Mechanisms of Entry and Nuclear Transport of Capsids
... nucleocapsid. Baculovirus enters insect cells via re- ceptor-mediated endocytosis (32, ...related baculovirus species (Ploidia inter- punctella granulosis virus) were observed docking at the nu- clear pore ...
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Responses of insect cells to baculovirus infection: protein synthesis shutdown and apoptosis.
... model of the responses of Ld652Y cells to AcMNPV infection (Fig. 7). Since protein synthesis shutdown and apoptosis ap- peared to be separate responses, two separate pathways were hypothesized. The specific ...
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Nuclear Marginalization of Host Cell Chromatin Associated with Expansion of Two Discrete Virus-Induced Subnuclear Compartments during Baculovirus Infection
... as baculovirus-infected cell nu- clei, are highly compartmentalized into functional units or nuclear ...structures. Baculovirus IE1 might also be able to gen- erate a network to form the IE1-accociated ...
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Baculovirus Infection Raises the Level of TATA-Binding Protein That Colocalizes with Viral DNA Replication Sites
... The transcriptional analysis demonstrated that the high level of TBP protein did not correlate with increased transcription of the TBP gene during the late phases of infection. Thus, it is conceivable that virus ...
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Enhancement of polyhedrin nuclear localization during baculovirus infection.
... Together, the results of these experiments suggest that there are at least three different factors that could contribute to the higher efficiency of polyhedrin nuclear localization at la[r] ...
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Nuclear IE2 Structures Are Related to Viral DNA Replication Sites during Baculovirus Infection
... the infection cycle than IE2, one might envision that DBP and LEF-3 structures assemble at preexist- ing IE2 nuclear ...in infection, there were always some dots that had no IE2 counterpart, suggesting that ...
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Transcriptome Responses of the Host Trichoplusia ni to Infection by the Baculovirus Autographa californica Multiple Nucleopolyhedrovirus
... The baculovirus Autographa californica multiple nucleopoly- hedrovirus (AcMNPV) has a large genome (⬃134 kbp) that en- codes ⱖ 156 ...AcMNPV infection is completed in a relatively short time period ...
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The GP64 envelope fusion protein is an essential baculovirus protein required for cell-to-cell transmission of infection.
... insects. Infection of the host begins when insect larvae acquire the virus ...orally. Infection is first observed in the epithelial cells of the midgut, and this is followed in most cases by systemic ...the ...
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Baculovirus VP1054 Is an Acquired Cellular PURα, a Nucleic Acid-Binding Protein Specific for GGN Repeats
... viral infection. To explore the role of VP1054 in the baculovirus infection cycle, we deleted the vp1054 gene from the AcMNPV ...tsVP1045 infection under nonpermissive conditions ...
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Reactive-Site Cleavage Residues Confer Target Specificity to Baculovirus P49, a Dimeric Member of the P35 Family of Caspase Inhibitors
... upon baculovirus infection of cultured Drosophila cells but still blocks apoptosis through inhibition of the down- stream effector caspases, including DrICE ...
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Identification of a Hydrophobic Domain of HA2 Essential to Morphogenesis of Helicoverpa armigera Nucleopolyhedrovirus
... of infection and then appeared within the nucleus (data not shown), and finally, microfilaments were transported to the cytoplasm and plasma membrane, again at a very late stage of infection ...of ...
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Gastrointestinal Delivery of Baculovirus Displaying Influenza Virus Hemagglutinin Protects Mice against Heterologous H5N1 Infection
... recombinant baculovirus with the immediate-early pro- moter 1 of WSSV was constructed to facilitate high-level ex- pression of influenza virus H5 hemagglutinin in both insect and mammalian ...the ...
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Baculovirus DNA Replication-Specific Expression Factors Trigger Apoptosis and Shutoff of Host Protein Synthesis during Infection
... of baculovirus DNA replication-induced apop- ...during infection or the detection of replicating viral DNA as damaged DNA are potent proapoptotic signals in vertebrates (reviewed in references 29, 30, and ...
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Synthesis of functional human immunodeficiency virus tat protein in baculovirus as determined by a cell-cell fusion assay.
... Abundant synthesis of functional human T-cell leukemia virus type I p4Y protein in eucaryotic cells by using a baculovirus expression vector.. A baculovirus vector can express intron-con[r] ...
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Cell Susceptibility to Baculovirus Transduction and Echovirus Infection Is Modified by Protein Kinase C Phosphorylation and Vimentin Organization
... With a confocal microscope, we monitored changes in the vi- mentin organization in response to the culture medium and PMA treatment. With thorough analysis of multiple cells, we were able to observe subtle but consistent ...
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