Bcl2-associated X protein
PROGNOSTIC VALUE OF BCL2 ASSOCIATED X PROTEIN (BAX) EXPRESSION IN ADULT EGYPTIAN PATIENTS WITH ACUTE MYELOID LEUKEMIA
... [2] groups, to allow tailoring of treatment strategies. Understanding of the molecular pathways that participate in the biology of leukemia may lead to the design of new therapies which may improve patients' survival ...
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Molecular pattern of lncRNAs in hepatocellular carcinoma
... BAX: BCL2-associated X protein; BRM: Brahma; CAMTA1: calmodulin binding transcription activator 1; c-CBL: casitas B- lineage lymphoma; ceRNA: competing endogenous RNA; CHIP: Carboxy- Terminus ...
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Original Article Identification of genes associated with apoptosis-sensitive acute lymphoblastic leukemia responsive to ionising radiation by bioinformatics analyses
... and protein-protein interaction (PPI) network was ...as BCL2-associated X protein (BAX) and Fas cell surface death receptor (FAS), were mainly enriched in the BP terms related to ...
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Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer
... Akt: protein kinase B; ARID3A: AT-rich inter- action domain 3A; BAX: BCL2 associated X protein, apoptosis regulator; BCL-xL: apoptosis inhibiting protein; BRCA1/2: DNA repair ...
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The determination of changes in the expression of genes for selected specific transcriptional factors in in vitro ductal breast cancer cells under the influence of paclitaxel
... – BCL2-antagonist/killer; Bax – BCL2-associated X protein; Bcl-2 – B-cell CLL/lymphoma 2; BRCA1 – breast cancer type 1 susceptibility protein; cDNA – complementary ...
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The role of death-associated protein 3 in apoptosis, anoikis and human cancer
... AKT/PKB: Protein kinase B; APAF1: Apoptotic protease activating factor 1; BAX: BCL2 associated X protein; BCL2: B-cell lymphoma 2 protein; BID: BH3 interacting domain ...
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Molecular mechanisms of HPV mediated neoplastic progression
... Activator protein 1; ATM: Ataxia telangiectasia mutated; ATR: Ataxia telangiectasia and Rad3-related protein; Bax: BCL2-associated X protein; BRCA1: Breast cancer type1; BRD4: ...
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A BCL2 promoter polymorphism rs2279115 is not associated with BCL2 protein expression or patient survival in breast cancer patients
... tumour BCL2 protein ex- pression and oestrogen has also been widely ...of BCL2 mRNA and protein, but down- regulation of Bcl-x(L) mRNA and protein ...the BCL2 family ...
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Clarification of the molecular pathway of Taiwan local pomegranate fruit juice underlying the inhibition of urinary bladder urothelial carcinoma cell by proteomics strategy
... Akt/PKB: protein kinase B; BAG2: BCL2-associated athanogene 2; BCL 10: B-cell lymphoma/leukemia 10; CAPZA1: F-actin-capping protein subunit alpha-1; CFL1: C ofilin; DUT: dUTP pyrophosphatase; ...
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More than just inflammation: Ureaplasma species induce apoptosis in human brain microvascular endothelial cells
... BAK: BCL2 homologous antagonist/killer; BAX: BCL2-associated X apoptosis regulator; BBB: Blood-brain barrier; BCL: B cell lymphoma; CCU: Color-changing units; CNS: Central nervous system; ...
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Pregnane X receptor activation potentiates ritonavir hepatotoxicity
... homologous protein (Chop), binding immunoglobulin protein (Bip), and cyclic AMP-depen- dent transcription factor 3 (Atf3) (Figure 4, B and ...genes associated with cell death and tissue injury, ...
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Molecular mechanisms of long non-coding RNAs in anaplastic thyroid cancer: a systematic review
... RNA; BCL2, BCL2 apoptosis regulator; CASC2, cancer susceptibility candidate 2; CCND1, cyclin D1; CDK6, cycling-dependent kinase 6; ceRNA, competing endogenous RNA; c-myc, avian myeocytomatosis virus ...
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The Diagnostic and Prognostic Impact of Serum miRNA 21 in a Sample of Hepatitis C/None Hepatitis Diffuse Large B Cell Lymphoma Egyptian Patients
... Background: Circulating microRNAs are potential biomarkers of diagnostic and prognostic impact in various inflammatory and malignant diseases. Aim: Linking in- flammation with malignancy, we studied miRNA-21 in sera of ...
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Expression of cardiac insulin signalling genes and proteins in rats fed a high-sucrose diet: effect of bilberry anthocyanin extract
... Using the multiple gene profiling feature of microarray analysis with real-time PCR quantitation techniques, we showed that expression of GLUT1, GLUT4, HK2, GLUT4 and Akt were down-regulated. Decreased ex- pression of ...
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Building Positive Future Orientations: The Role of Natural Mentors in the Lives of African American Girls
... and signaling proteins is essential for the regulation of cell motility and control of apoptosis. The importance of tyrosine phosphorylation in B. bacilliformis infection of host cells also has been demonstrated. Initial ...
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S100, bcl2 and myeloperoxid protein expirations during periodontal inflammation
... Elevated bcl2 expression levels can prevent cellular apoptosis, thereby inducing inflammatory cells to remain locally in the periodontal tissue, causing consequent ex- cessive cytokine secretion which leads to the ...
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BCL2 and hsa miR 181a 5p are potential biomarkers associated with papillary thyroid cancer based on bioinformatics analysis
... related protein 4 (LRP4) [6] and tektin 4 (TEKT4) [7], whose downregulation can sig- nificantly inhibit the proliferation, migration, and invasion of PTC ...
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BCL2 and P53 immunoexpression in colorectal carcinoma
... detect BCL2 and P53 expression and was applied to formalin- fixed, paraffin embed- ded tissues, with each batch of stain positive and negative control sections were ...For BCL2, positive controls were ...
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ROLE OF BCL-2 IN ORAL SQUAMOUS CELL CARCINOMA: A SYSTEMATIC REVIEW
... Bcl-2 protein is one of the most assuring anti- apoptotic proteins expressed in OPMD’s and OSCC. Most of the articles reviewed in this research suggested that the expression of Bcl-2 might be used as a prognostic ...
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Expression levels of the <em>BAK1</em> and <em>BCL2</em> genes highlight the role of apoptosis in age-related hearing impairment
... Abstract: Age-related hearing impairment (ARHI) is a progressive and a common sensory disorder in the elderly and will become an increasingly important clinical problem given the growing elderly population. Apoptosis of ...
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