beta-adrenergic receptor
Hypoxia and glucose independently regulate the beta adrenergic receptor adenylate cyclase system in cardiac myocytes
... the beta-adrenergic receptor (beta AR)-adenylate cyclase system in a model of hypoxic injury in cultured neonatal rat ventricular ...surface beta AR density (3H-CGP-12177) decreased ...
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Parainfluenza 3 Infection Blocks the Ability of a Beta Adrenergic Receptor Agonist to Inhibit Antigen induced Contraction of Guinea Pig Isolated Airway Smooth Muscle
... Guinea pigs, actively sensitized to ovalbumin, were inoculated by nasal insufflation with parainfluenza 3 or virus growth medium 4 d before performing in vitro pharmacological studies on tracheal and bronchial smooth ...
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Elevation of beta adrenergic receptor density in human lymphocytes after propranolol administration
... membranes. Receptor density was quantitated by direct binding assays with the radioligand ...of beta-adrenergic receptors had increased 43 +/- 4% (P less than ...of beta-adrenergic ...
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Hypothyroidism modulates beta adrenergic receptor adenylate cyclase interactions in rat reticulocytes
... thyroidectomy. Beta adrenergic receptor interactions were assessed by measuring the number of (-)[3H]-dihydroalprenolol binding sites and the ability of an agonist to compete for occupancy of the ...
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Rapid desensitization of neonatal rat liver beta adrenergic receptors A role for beta adrenergic receptor kinase
... of beta-adrenergic receptors (BAR) to agonists often leads to a rapid loss of receptor ...rapid receptor desensitization include receptor phosphorylation by either cAMP-dependent ...
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Reduced beta adrenergic receptor activation decreases G protein expression and beta adrenergic receptor kinase activity in porcine heart
... in beta-adrenergic receptor-dependent stimulation of adenylyl cyclase and a persistent high affinity state of the beta-adrenergic ...ventricular beta-adrenergic ...
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Impaired beta adrenergic receptor binding and function in cystic fibrosis neutrophils
... abnormal adrenergic and cholinergic physiologic responses in addition to decreased beta adrenergic-induced cyclic AMP generation in human ...assessing beta adrenergic receptor ...
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An antiidiotypic antibody that recognizes the beta adrenergic receptor
... adrenergic receptor. Allotype-identicaL rabbits were immunized with this fraction. After 6 mo, antisera exhibited antiidiotypic activity inhibiting [3H]alprenolol binding to the original antibody and to ...
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Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma
... vitro [53]. Pharmacokinetic data suggests that in patients treated with propranolol the peak serum concentrations range from 200-400 ng/ml, which is equivalent to 0.77- 1.5µM [54]. There are many possible explanations ...
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Pharmacodynamic Effects of Beta Adrenergic Receptor Blockade in Patients with Hyperthyroidism
... The effects of isoproterenol on the individual heart rates, cardiac indexes, and mean arterial and mean right atrial pressures of three additional patients before, 10 minutes after intra[r] ...
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Pinpointing beta adrenergic receptor in ageing pathophysiology: victim or executioner? Evidence from crime scenes
... in receptor density on lymphocyte mem- branes taken from subjects between the ages of twenty and eighty years ...the receptor and post receptor levels, with parallel modifications in membrane ...
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The Glucose Receptor A DEFECTIVE MECHANISM IN DIABETES MELLITUS DISTINCT FROM THE BETA ADRENERGIC RECEPTOR
... pancreatic beta adrenergic receptors and the implications of this relationship with regards to abnormal insulin secretion in diabetes mellitus, two questions were ...upon beta adrenergic ...
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Beta adrenergic receptor blockade of feline myocardium Cardiac mechanics, energetics, and beta adrenoceptor regulation
... during beta-adrenergic stimulation under fixed mechanical ...that beta-blockade may reduce oxygen consumption through effects independent of its influence on mechanical conditions and contractile ...
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Beta-adrenergic receptor stimulation limits the cellular proarrhythmic effects of chloroquine and azithromycin
... that beta-adrenergic stimulation could be a potential protective factor against CQ- and AZM-induced proarrhythmia by lowering the APD prolongation and preventing the occurrence of ...of ...
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Impaired formation of beta adrenergic receptor nucleotide regulatory protein complexes in pseudohypoparathyroidism
... H, receptor (R), and N. To test this hypothesis, we compared beta-adrenergic agonist-specific binding properties in erythrocyte membranes from five patients with PHP-Ia (N = 45% of control), five ...
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Beta adrenergic receptor polymorphisms: A basis for pharmacogenetics
... β- adrenergic receptors may alter the response to β-adren- ergic stimulation and ...to receptor po- lymorphism. Better understanding of β-adrenergic rece- ptor function will help to optimize therapy ...
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The Role of Beta-Adrenergic Receptor Blockers in Autism
... Extracellular dopamine increased following the intrastriatal infusion of NOS substrate [94]. Increased RBC NO levels and plasma GSH peroxidase (GSH-Px) were detected in patients with autism [95]. In addition, GSH plasma ...
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Exercise induced pulmonary vasoconstriction during combined blockade of nitric oxide synthase and beta adrenergic receptors
... We studied the effects of inhibition of nitric oxide (NO) (endothelium-derived relaxation factor) synthase in combination with alpha and beta adrenergic receptor blockade on pulmonary vascular tone ...
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Beta adrenergic neuroeffector abnormalities in the failing human heart are produced by local rather than systemic mechanisms
... myocardial adrenergic receptors, adrenergic neurotransmitters, and beta-adrenergic receptor-effector responses in nonfailing and failing hearts taken from nonfailing organ donors, ...
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Adrenergic receptor control mechanism for growth hormone secretion
... Alpha adrenergic blockade with phentolamine during insulin hypoglycemia, ...U/kg). Beta adrenergic blockade with propranolol during insulin hypoglycemia significantly enhanced HGH concentrations in ...
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