Biliary Tract Cancer
Clinical Outcome of Patients with Advanced Biliary Tract Cancer in a Dedicated Phase I Unit.
... phase I unit may be considered, to allow patients to enter trials before the natural course of the disease reaches this in fl exion point. It is interesting to note that ABC patients who did eventually enter a phase I ...
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Bile Acid Analysis in Biliary Tract Cancer
... We found that the proportion of secondary bile acids, the most strongly suspected carcinogens, were low in bile from subjects with biliary tract cancer. Theoretically, this is because primary bile ...
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Relationship between UGT1A1*6/*28 polymorphisms and severe toxicities in Chinese patients with pancreatic or biliary tract cancer treated with irinotecan-containing regimens
... pancreatic, biliary tract, and gastric ...or biliary tract cancer, who were administered irinotecan-containing regimens as the second- or third-line ...
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New and emerging treatment options for biliary tract cancer
... Abstract: Biliary tract cancer (BTC) is a group of relatively rare tumors with a poor prognosis. The current standard of care consists of doublet chemotherapy (platinum plus gemcitabine); however, ...
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Phase I clinical trial of multiple peptide vaccination for patients with advanced biliary tract cancer
... Biliary tract cancer (BTC) is not a common disease world- wide, but is prevalent in East Asia and Latin ...Recently, cancer vaccines using synthetic peptides have been undergoing development ...
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Endoscopic inside stent placement is suitable as a bridging treatment for preoperative biliary tract cancer
... primary biliary tract cancer for the following ...distal biliary strictures have pancreatic or ampullary cancer, and the placement of an inside stent in the biliary stricture ...
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Practical Use of Gemcitabine and Cisplatin Combination Therapy as First Line Treatment for Japanese Patients with Advanced Biliary Tract Cancer
... Biliary tract cancer (BTC) is a rare type of cancer world- wide, but it is more common in East Asia and Latin America than in other regions ...from cancer [2] and its prevalence is ...
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The efficacy of fluoropyrimidine-based adjuvant chemotherapy on biliary tract cancer after R0 resection
... on Cancer (AJCC) Cancer Staging Manual (7th edition), lymph nodal status, preoperative serum carbohydrate antigen 19-9 (CA 19-9) level, and chemotherapeutic agents, were ...
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Transcatheter arterial chemoembolization with gemcitabine and oxaliplatin for the treatment of advanced biliary tract cancer
... Between July 2009 and December 2013, a total of 65 patients with advanced BTC were included in the current study. Baseline patient characteristics are reported in Table 1. The study population included 38 men and 27 ...
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<p>Efficacy and safety of nivolumab for metastatic biliary tract cancer</p>
... Patients were followed up till progression, death due to any reason, treatment interruption due to intolerable toxicity, or till the cut-off date of September 1, 2018. Disease progression and new lesion development were ...
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PHOTOSTENT-02: porfimer sodium photodynamic therapy plus stenting versus stenting alone in patients with locally advanced or metastatic biliary tract cancer
... malignant biliary obstruction, and that the use of porfimer sodium PDT Figure 2 Kaplan-Meier estimates of (A) overall survival and (B) progression-free survival by treatment ...
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Tumor growth effects of rapamycin on human biliary tract cancer cells
... Rapamycin acts by inhibiting the mTOR signaling pathway, as described above. This pathway is already known to be upregulated in various carcinoma cell lines, such as lung cancer, renal cancer, ovarian ...
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Prognostic factors for operable biliary tract cancer: serum levels of lactate dehydrogenase, a strong association with survival
... the biliary tract, there were no statistically significant differences between LDH and OS in multivari- ate analysis in individual ...the biliary tract did not affect ...
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<p>Completely resolved advanced biliary tract cancer after treatment by pembrolizumab: a report of two cases</p>
... lung cancer, pembrolizumab induced overall response rates of 19 – ...cervical cancer, recurrent locally advanced gastric or gastroesophageal junction adenocarcinoma, recurrent or metastatic head and neck ...
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HER2/neu-directed therapy for biliary tract cancer
... For subjects with adequate biopsy tissue, an amplicon library was generated from 10 ng of DNA from each sample using the Ion Ampliseq Cancer Panel (Life Tech- nologies, Carlsbad, CA, USA). FFPE cell pellets of the ...
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A nomogram to predict overall survival for biliary tract cancer
... Several variables, including demographics (age, sex, race); tumor grade; marital status; T, N, and M stage; tumor site (cholangiocarcinoma, ampulla of Vater cancer, and gall- bladder cancer); and treatment ...
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Biliary tract cancer: current challenges and future prospects
... Purpose: Incidence and mortality of biliary tract carcinoma (BTC) are increasing, especially in South America and Asia. Such a disease often bears a dismal prognosis because of diagnosis occurring at late ...
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Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tract
... in Biliary Carcinomas We analyzed alterations in gene expression in EHC, IHC, and GBC compared with non-cancerous bile duct or gall- bladder controls using the Human Genome U133A Gene- ...of biliary ...
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Aspirin use is associated with a reduced risk of cholangiocarcinoma: a systematic review and meta-analysis
... duct cancer or biliary tract cancer as the outcome; accessible OR/risk ratio (RR) values and corresponding 95% CIs or adequate data for ...
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Two cases of intrahepatic cholangiocellular carcinoma with high insertion-deletion ratios that achieved a complete response following chemotherapy combined with PD-1 blockade
... BTC: Biliary tract cancer; CIT: Combination of chemotherapy with an immune checkpoint blocker; CNVs: Copy number variations; CR: Complete response; DCR: Disease control rate; dMMR: DNA mismatch ...
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