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Biochemical and Bioprocess

Physical property indices to guide bioprocess synthesis and design

Physical property indices to guide bioprocess synthesis and design

... My supervisor. Professor Peter Dunnill, once said to me that: “The only thing you can write is what you see - that only - what you saw happen on the bench in front of you - just that. Everything else is opinion”. Thus ...

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Improvement of bioprocess monitoring: development of novel concepts

Improvement of bioprocess monitoring: development of novel concepts

... of bioprocess monitoring will play a crucial role to meet the future requirements of bioprocess ...of bioprocess monitoring reveals that only a limited number of metabolic variables show a close ...

11

Prediction of bioprocess production using deep neural network method

Prediction of bioprocess production using deep neural network method

... The escherichia coli model iJO1366 in system biology markup file is imported into FBA to get the respected growth rate and xylitol production of the organisms. Furthermore, gene deletion has been implemented to predict ...

9

Accelerated Bioprocess Development

Accelerated Bioprocess Development

... h, using feeding profile, feed rate, initial substrate concentration and hunger phase data. the applied experimental conditions, leading to high EPG activity and low ethanol 291.[r] ...

23

Developing a mesophilic co-culture for direct conversion of cellulose to butanol in consolidated bioprocess

Developing a mesophilic co-culture for direct conversion of cellulose to butanol in consolidated bioprocess

... CBP of cellulosic feedstock for butanol production using mesophiles offers additional advantages in processing over the use of thermophilic microbial systems in terms of potential savings on capital and operating costs ...

9

Implementation and use of cloud-based electronic lab notebook in a bioprocess engineering teaching laboratory

Implementation and use of cloud-based electronic lab notebook in a bioprocess engineering teaching laboratory

... The bioprocess engineering lab course is a graduate course offered to students in the Master of Biotechnology Program at Northwestern University. The lab course includes hands- on training in bench-scale upstream ...

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Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping

Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping

... Background: The throughput of cultivation experiments in bioprocess development has drastically increased in recent years due to the availability of sophisticated microliter scale cultivation devices. However, as ...

11

Bioprocess Control in Microscale: Scalable Fermentations in Disposable and User-Friendly Microfluidic Systems

Bioprocess Control in Microscale: Scalable Fermentations in Disposable and User-Friendly Microfluidic Systems

... To further improve the application of MTPs as micro- bioreactors, active process control has been implemen- ted. Buchenauer et al. [15] have described a microfluidic chip, replacing the bottom of a conventional MTP, ...

13

An automated workflow for enhancing microbial bioprocess optimization on a novel microbioreactor platform

An automated workflow for enhancing microbial bioprocess optimization on a novel microbioreactor platform

... Reliable results for early upstream bioprocess develop- ment are normally achieved in stirred tank reactors with well-defined environment. To characterize protein pro- duction processes in the MTP cultivation ...

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Nonlinear Control of Bioprocess Using Feedback Linearization, Backstepping, and Luenberger Observers

Nonlinear Control of Bioprocess Using Feedback Linearization, Backstepping, and Luenberger Observers

... The paper is organized as follows. Section 2 presents the bioprocess model for control design. Theoretical foundation of input-output feedback linearization (FBL) and controller design are outlined in Section 3 ...

14

Bioprocess for semi-industrial production of immunomodulator polysaccharide pleuran by pleurotus ostreatus in submerged culture

Bioprocess for semi-industrial production of immunomodulator polysaccharide pleuran by pleurotus ostreatus in submerged culture

... The process developed in this study shows high potential for industrial scale production o f the EPS pleuran in submerged culture with significant reduction of batch production time [r] ...

8

Bioprocess optimization for biomass production of probiotics yeast Saccharomyces boulardii in semi industrial scale

Bioprocess optimization for biomass production of probiotics yeast Saccharomyces boulardii in semi industrial scale

... boulardii in shake flask using five different cultivation media, followed by medium optimization study using different concentration of glucose, corn steep liquor and sodium nitrate in s[r] ...

11

Bioprocess strategy for the production of Lactobacillus Rhamnosus NRRL B442 high cell-beta-glucosidase activity

Bioprocess strategy for the production of Lactobacillus Rhamnosus NRRL B442 high cell-beta-glucosidase activity

... a bioprocess strategy to overcome the limitations and to control the key factors identified for the improvement of CBG ...the bioprocess strategy ...

36

Bioprocess Development Employing Design of Experiments for Antibiotic Production from Streptomyces parvulus Strain Sankarensis-A10

Bioprocess Development Employing Design of Experiments for Antibiotic Production from Streptomyces parvulus Strain Sankarensis-A10

... parvulus strain sankarensis-A10 by optimization of medium and fermentation conditions employing traditional and DOE approaches, which ultimately lead to the production of more than on[r] ...

10

Bioprocess conditions for Ethanol production from Banana waste using Bacillus subtilis in shake flask fermentation

Bioprocess conditions for Ethanol production from Banana waste using Bacillus subtilis in shake flask fermentation

... Bacillus subtilis strain obtained from Laboratory of Biochemical Engineering Department at the University of Baghdad, Al-Khwarizmi College of Engineering, Baghdad, Iraq. These strains have been preserved at -80°C ...

9

A BIOPROCESS DEVELOPMENT STUDY OF POLYPHENOL PROFILE, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF KOMBUCHA ENRICHED WITH Psidium guajava L.

A BIOPROCESS DEVELOPMENT STUDY OF POLYPHENOL PROFILE, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF KOMBUCHA ENRICHED WITH Psidium guajava L.

... Kombucha fermented on guava juice substrate showed a higher fresh and dry weight, then followed by black tea and finally the kombucha fermented on green tea substrate are the lowe[r] ...

7

Osteogenic commitment of Wharton’s jelly mesenchymal stromal cells: mechanisms and implications for bioprocess development and clinical application

Osteogenic commitment of Wharton’s jelly mesenchymal stromal cells: mechanisms and implications for bioprocess development and clinical application

... CM: Conditioned media; EV: Extracellular vesicle; FDR: False discovery rate; GMP: Good manufacturing practice; ISCT: International Society for Cell and Gene Therapy; MSC: Mesenchymal str[r] ...

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Production of Cytomegalovirus Dense Bodies by Scalable Bioprocess Methods Maintains Immunogenicity and Improves Neutralizing Antibody Titers

Production of Cytomegalovirus Dense Bodies by Scalable Bioprocess Methods Maintains Immunogenicity and Improves Neutralizing Antibody Titers

... The protein compositions of multiple lots of GT-DB and TFF-DB were analyzed by several methods (Fig. 3E to I, Tables 1 and 2, and data not shown). Protein lysates were evaluated by their reactivity against a ...

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Bioprocess And Medium Optimization For Glutamic Acid Production Using Submerged Fermentation In Shake Flask And Bioreactor

Bioprocess And Medium Optimization For Glutamic Acid Production Using Submerged Fermentation In Shake Flask And Bioreactor

... [13]. Dailin, D. J., Elsayed, E. A., Othman, N. Z., Malek, R., Phin, H. S., Aziz, R., Mohamad Wadaan & El Enshasy, H. A. (2016). Bioprocess development for kefiran production by Lactobacillus kefiranofaciens ...

5

BIOCHEMICAL DIAGNOSIS OF ALCOHOLISM

BIOCHEMICAL DIAGNOSIS OF ALCOHOLISM

... Only high alcohol intake group of alcoholic liver disease showed significant decrease in ascorbic acid content of serum in comparison to normal healthy persons and non-alcoholic liver di[r] ...

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