The increase in bloodglucose level 1 hour postinduction (T2) and 1 hour postoperative (T3) shown in table 4.2 in the treatment group did not show statistically significant results with a value (p > 0.05), while in the control group the results were significant with the value (p < 0.05). This is consistent with the research conducted by Perrone, et al. (2011) who concluded that an increase in bloodglucoselevels was lower in the treatment group who received oral glucose solution at night and morning before surgery compared with the control group. From these results, it indicates that oral glucose administration before surgery has a significant effect in suppressing increased bloodglucoselevels postoperatively. This is very useful for preventing morbidity caused by hyperglycemia.
Abstract: Furosemide is a diuretic and is often used in the treatment of hypertension. This medicine is very good when it comes to lowering the blood pressure, and this is also a drug of choice when it comes to the stage of hypertensive urgencies and emergencies. It can be administered intravenously, and the effects reach a maximum within 30 minutes. Due to the fact that this medicine causes a loss of potassium ions it can also affect the reduction of insulin in the blood, and thus the increase in bloodglucose and arrhythmias. A prospective random study was carried out in Emergency Medical Service of Public Health Institution Center “Zivinice’’, where we analyzed 120 patients which were suffering from hypertension heart disease, and diabetes. We included all 120 patient whom suffering from hypertension and diabetes starting February till end of July 2016. Data for analysis: age, gender, bodymass index, analysis of the arterial blood pressure value, characteristic laboratory changes, analysis of electrocardiography. Looking at all the three groups of patients, it can be noticed that the maximum value of arterial blood pressure upon arrival at the Emergency Medical service had patients suffering from hypertension and diabetes, where the average value of arterial blood pressure was 173/113 mmHg. According to analysis for all three observed groups of patients, after treatment with furosemide there is no statistical significance in the incidence of arrhythmias between the groups where. Looking at the summary for all three groups of patients, the average value increase of bloodglucose after treatment with furosemide is 0.7 mmol/l. Furosemide is safe for the treatment of hypertension in diabetic patients. It does not cause an increase in bloodglucoselevels.
Diabetic patients were those who had previously been diagnosed by having had two fasting bloodglucose lev- els of >7.0 mmol/L, but who did not require insulin for management and had not had ketonuria in the previous six months. All respondents were measured for weight, height and truncal circumferences. The body mass index (BMI) and waist-hip (W-H) ratios were calculated and random bloodglucoselevels were clinically determined. Blood pressure was measured as three supine readings taken at 5 minute intervals. Diastolic pressure was meas- ured as Korotkoff phase 5.
cycle ergometer efforts separated by rest) on bloodglucose during exercise and in the immediate 1-hour postexercise period. Participants injected their normal dose of insulin and had breakfast. After the postprandial peak in bloodglucose, on alternate days, participants either exercised or rested. During exercise bloodglucose declined more rapidly as compared to the nonexercising controls, indicating that high intensity exercise may increase the risk of hypoglcemia. This finding is not supported by the other studies reviewed. However during the recovery period bloodglucoselevels continued to decline in the controls while remaining stable in the exercise group suggesting a decreased risk of postexercise hypoglycemia. Guelfi et al 56 also compared a HIT protocol that was com-
CONCLUSION: Thus the present study establishes that Roflumilast is effective in lowering bloodglucoselevels significantly in streptozotocin induced diabetic albino rats and comparable to the standard hypoglycemic drug, glibenclamide. The mechanisms such as enhanced intestinal GLP-1 secretion and amplification of the insulin-secretory response in the pancreas can be a leading novel and promising combination concepts for treating type 2diabetes.
Conclusion: Current study evidences that the organotherapic drug obtained from the pancreas of a young pig, diluted 1x10 12 in alcohol/ water 8% improves bloodglucoselevels in patients with hyperglycemia keeping within the normal range after four months of treatment. Considering the HAART therapy that significantly increases the life expectancy of AIDS patients but with significant metabolic alterations this study shows the possibility of utilization of complementary and alternative therapies. Although results indicate a significant effect of the organotherapic drug, additional studies are needed to evaluate the long-term effects.
Results from analysis indicate that obesity is a signifi- cant predictor for risk of periodontal disease. Hence, periodontists need to be aware of the potential health problems related to obesity and increase blood glu- cose level and should take them into account during treatment. Periodontists should counsel obese persons regarding the possible oral complications of obesity and abnormal bloodglucose level. Finally, intervention and prevention approaches may ultimately lead to amelio- ration of the significant health burden associated with obesity, elevated bloodglucoselevels, and periodontitis.
Hypoglycemia and related symptoms may occur at varying bloodglucoselevels for each individual. Most diabetes healthcare professionals recommend treating for hypoglycemia when symptoms are present or bloodglucoselevels fall below 70 mg/dL. Left untreated, bloodglucoselevels continue to drop, symptoms worsen, and you may feel faint or pass out. It’s important to become aware of how your body feels when hypoglycemia is occurring, so you are prepared to treat the symptoms immediately and effectively.
diabetic status influences the mortality. Moreover there is a positive correlation between the bloodglucoselevels and a poor outcome as the patients in high bloodglucose group had high killip class and low mean Left ventricular ejection fraction. These results were supported by many previous studies especially the one done by Hafiner et al in which the patients with diabetes have two times high incidence of myocardial infarction and these patients also have four times high mortality
The most common form of diabetes, type II can be prevented, or controlled to some extent with a healthy lifestyle, which means enjoying healthy easting, maintaining a healthy weight, and being physically active. Healthy eating involves developing a plan to control glucose intake, lower cholesterol, and improve overall health. In particular, meals should include at least one food with low Glycemic Index (G.I) such as grainy bread, cereals and some fruits to balance bloodglucoselevels. These low G.I. foods provide a steady release of glucose into the blood, as they contain more complex carbohydrates, which take longer to digest. For a healthy diet, diabetics in particular but also all other people should limit the amount of medium to high G.I. foods, like those that contain large amounts of sucrose or table sugar and glucose, as these foods can rapidly change the glucoselevels in the blood.
Effect of aqueous and alcoholic extracts of Eugenia jambolana leaves on fasting bloodglucoselevels (mg/dl) of nicotinamide-streptozotocin-induced diabetic rabbits is given in Table 2. It is worthy to mentioned that animals treated with glibenclamide (3 mg/kg) showed highly significant reduction in bloodglucose level (p<0.01). There was no significant effect of aqueous extract of Eugenia jambolana leaves on fasting bloodglucoselevels through out the 30 days, when compared with the diabetic control. However, there was highly significant reduction 64% (p<0.01) in fasting bloodglucoselevels of alcoholic extract-treated animals, when compared with the diabetic control. Table 2: Effect of aqueous and alcoholic extracts of Eugenia jambolana leaves on fasting bloodglucoselevels (mg/dl) of nicotinamide-streptozotocin-induced diabetic rabbits (mean ± SEM).
Several efforts can be done to control bloodglucose and prevent early. Bloodglucose level measurements are examined in the laboratory or using glucometers. The measurement is done by injuring the limbs that is known as the invasive method. At present, there is a growing detection of bloodglucoselevels with non- invasive methods (without injuring the body) [5-21]. This method is an alternative for patients who are not comfortable using injection with relatively more affordable cost.
The present study was undertaken to evaluate the efficiency of gingival crevicular blood (GCB) for assessment of bloodglucose level as a chairside test in the dental clinics and evalu- ate the influence of Phase I periodontal therapy on the glycemic control of diabetic subjects. A comparative evaluation of glucoselevels of gingival blood and fingerstick capillary blood was done before the periodontal therapy and 45 days after the periodontal therapy. Totally, 50 known diabetic patients having untreated moderate-to-severe periodontitis in the age group of 25 to 60 years from the Department of Periodontology and Implanto- logy, D. J. College of Dental Sciences and Research, Modinagar, India, were selected for the study. Patients requiring antibiotic premedication, any disorder that is accompanied by an abnor- mally low or high hematocrit, having intake of substances that interfere with the coagulation system, severe cardiovascular, hepatic, immunologic, renal, hematological, or other organ disorders were excluded from the study. Glucoselevels were measured from the gingival blood using glucometer and from the capillary blood (finger puncture method) using glucometer during dental examination. Phase I periodontal therapy was carried out in all the patients, and the bloodglucoselevels were measured at baseline and 45th day after the periodontal treat- ment. Using statistical analysis, the glucoselevels of GCB and capillary bloodglucoselevels were analyzed and compared. The analysis showed no statistically significant difference in bloodglucoselevels between the two above-mentioned groups. With this study, we can arrive at the conclusions that GCB can provide an acceptable source for measuring bloodglucose in the study’s specific glucose self-monitor, and it can be used for the dental office evaluation of bloodglucose level. A better glycemic control is observed in diabetic subjects after the Phase I periodontal therapy. Hence, prevention and control of
Converting Enzyme inhibition) trial, patients with stable coronary artery disease had a significantly lower incidence of new-onset diabetes when randomised to trandalopril than the placebo over a median follow-up period of 4.8 years . In the Ramipril-based versus Diuretic-based Antihypertensive Primary Treatment in Patients with Pre-diabetes (ADaPT) Study , both treatments were equally effective in reducing BP and new-onset diabetes was less frequent in the ramipril than in the diuretic group at the 4 year follow-up. However no significant differences were found for a change in HbA1c as well as for fasting bloodglucoselevels during follow-up . Among the several meta-analyses [21–24] of which the one by Al-Mallah  is the most comprehensive and the one by Tocci  is the most recent one. The results of both meta-analyses were virtually identical although Al-Mallah also included results of trials with active comparators (diuretics, beta-blocker, and calcium channel blockers) while Tocci only considered placebo controlled trials. Al-Mallah reported a relative risk of 0.78 (95% CI 0.70–0.88) for the development of diabetes with ACE inhibitors and a relative risk of 0.8 (95% CI 0.75–0.86) for ARBs versus non-RAS based treatments . In the analysis by Tocci both ACE inhibitors and ARBs reduced new-onset diabetes as compared to placebo . Given that 50 to 100 patients have to be treated with RAS blocking agents to prevent one case of new onset diabetes . For this purpose the oral glucose tolerance test (OGTT) is useful but it is not convenient under daily practice conditions and the determination of fasting glucose or the HbA1c alone yields low sensitivity (62 and 58% respectively) .
Abstract: Objective: This study aimed to investigate the efficacy of Liraglutide on insulin resistance, physical dis- tribution and oxidative stress level in patients with type 2 diabetes mellitus (T2DM) complicated with metabolic syndrome (MS). Methods: In total, 86 patients with T2DM complicated with MS in our hospital were selected as the study subjects. The patients were divided into control group (CG) (n = 43) and research group (RG) (n = 43) in accordance with a random number table. The patients in the CG received metformin. The patients in RG received Liraglutide. Bloodglucoselevels, blood lipid levels, insulin resistance, physical distribution, oxidative stress levels were compared between the two groups. Results: FBG, 2hPPG and HbA1c in both groups dramatically decreased after treatment. The three measures in RG were lower than those in CG (P < 0.05). TG, TC and LDL-C levels reduced and HDL-C level increased. The TG, TC and LDL-C levels in CG were higher than those in RG (P < 0.05). HOMA-IR reduced and HOMA-β increased. The level of HOMA-IR in RG was lower than that in CG (P < 0.05). The level of HOMA-β was higher than that in CG (P < 0.05). Weight, body mass index and waistline reduced. The three measures in CG were higher than those in RG (P < 0.05). Urine 8-isoprostaines F2α and MDA remarkably reduced and T-AOC significantly increased compared with those before treatment. The 8-isoprostaines F2α and MDA in RG were lower than those in CG (P < 0.05). The level of T-AOC was higher than that in CG (P < 0.05). Conclusion: Liraglutide can significantly improve the postprandial bloodglucose, bloodglucose level, insulin resistance and physical distribu- tion of T2DM patients with MS. Its effect may be related to the improvement of oxidative stress levels in the body.
The bloodglucoselevels were checked every seven days. After continuously administrated drugs for 28 days, all mice were fasted overnight (18 - 24 hours), and their blood was drawn from the orbital sinus after anesthetization with ether and collected into the tubes containing potassium oxalate and sodium fluoride. These indexes including the blood insulin, glucose and fructosamine levels, Fe 2+ and total iron content, blood total cholesterol,
The Background: Tramadol, is a central acting analgesic that possesses weak affinity for the µ-opioid receptor and modifies transmission of nociceptive impulses through inhibition of monoamine reuptake. This study was designed to determine the effect of tramadol on bloodglucoselevels and also to investigate whether or not alpha-2 adrenergic re- ceptors were responsible for this effect. Methods: Twenty-five Wistar male rats were assigned to four groups to receive: Group I: saline; Group II: tramadol (1 mg·kg −1 ); Group III and Group IV: pretreatment with
Methods: This was a cross-sectional study with a sample size of 62 people selected by non-random sampling method on a consecutive basis, patients with acute stroke were taken blood to measure bloodglucoselevels, HbA1c, Hb and Leucocytes when entering the hospital room. Outcomes were assessed using NIHSS and MRS. The calculation of NIHSS and MRS scores was performed on the first day of admission and the fourteenth day. To analyze the correlation of blood sugar levels during HbA1c, Hb and leukocytes in acute stroke, this study used Spearman's correlation test. The p value <0.05 was considered statistically significant.
Relatively large sample size, community-based popula- tion, and the ﬁ rst attempt to show the modi ﬁ cation of bloodglucoselevels when higher blood pressure level increases arterial stiffness are strengths of this study. However, several limitations should be noted. The limitation of our analysis is its cross-sectional design. We can only ﬁ nd the correlations between variables by regression analysis. More research is needed to reveal the cause – effect relationship. In our work, to avoid excessive collinearity that may make the models robust, we adjusted for some important confounding factors which could increase the arterial stiffness. But we did not control for the phase of the menstrual cycle in premenopausal women, this causes variations in blood pressure and vascular function. And we did not control for caffeine, alcohol con- sumption or any unaccustomed physical activity 24-h before each visit. This plays a role in vascular function.
length was measured and they were ear tagged with indi- vidual numbers. Mean age at data collection was 19.45 (SD = 7.86) hours. Blood sampling was performed first to minimize the impact of stress on blood-glucoselevels. A droplet of blood was collected by puncture of Vena subcutanea abdominis  and blood-glucoselevels (mmol/l) were analyzed with the handheld glucometer Contour next USB (Bayer Consumer Care AG, Peter Merian-Strasse 84, 4052 Basel, Switzerland). If it was not possible to get enough blood form Vena subcutanea abdominis, blood was collected by puncture of Vena cephalica. Weights were recorded in grams rounded to the nearest 10 g (EKS premium 8006 GR-ST), and length measured in centimeters from Crista nuchalis to the first coccygeal vertebrae (crown to rump length). The piglets were given an IUGR-score based on head morphology as described by Chevaux et al. and Hales et al [16, 21]; the criteria that characterize growth restriction in piglets are 1) steep, dolphin-like forehead, 2) bulging eyes, and 3) wrinkles perpendicular to the mouth. Piglets with no sign of intrauterine-growth restriction were given score 1 (normal), piglets with one or two characteristics of intra- uterine growth restriction were given score 2 and piglets with all the characteristics of intrauterine growth restric- tion were given score 3. Piglets with IUGR score 3 are hereafter called IUGR-piglets.