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Bone Collagen

Chronic arthritis leads to disturbances in the bone collagen network

Chronic arthritis leads to disturbances in the bone collagen network

... lamellar bone, thus providing maximal strength to the structure ...array, collagen has the ability to generate a sec- ond-harmonic signal ...like collagen superhelix, is not symmetrical, the ...

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Biochemical markers of bone collagen type I metabolism

Biochemical markers of bone collagen type I metabolism

... the bone marrow also performs blood cell production and functioning of the immune system ...[10]. Bone has a complex ...(25%). Bone calcium and phosphorus are presented in the hydroxyapatite Ca 10 ...

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Abnormal cancellous bone collagen metabolism in osteoarthritis

Abnormal cancellous bone collagen metabolism in osteoarthritis

... of bone and the deposition of in- creased collagen may be features of other bones in OA sub- ...increased bone den- sity in OA, which they suggest protects against hip ...increased bone ...

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Development of clinical utility of zoledronic acid and patient considerations in the treatment of osteoporosis

Development of clinical utility of zoledronic acid and patient considerations in the treatment of osteoporosis

... BAP, bone alkaline phosphatase; BCE, bone collagen equivalents; BMD, bone mineral density; BSAP, bone specific alkaline phosphatase; BTMs, bone turn over markers; CTx, Serum type ...

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A Multi-isotope Investigation of Two Medieval German Populations: Insight into the Relationship Among Diet, Disease, and Tissue Isotopic Compositions

A Multi-isotope Investigation of Two Medieval German Populations: Insight into the Relationship Among Diet, Disease, and Tissue Isotopic Compositions

... and bone, thyroid, and kidney ...fragmentary bone pieces, slices, and sections. As a result, a single bone type could not be sampled consistently, and lesions of interest were usually not ...Cortical ...

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25 hydroxycholecalciferol enhanced bone maturation in the parathyroprivic state

25 hydroxycholecalciferol enhanced bone maturation in the parathyroprivic state

... In vitro evidence presently favors a direct osteolytic effect of biologically active vitamin D metabolites. Studies were designed to evaluate the effect of 25-hydroxycholecalciferol (25OHD3) on bone ...

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Mineral deposition and vascular invasion of hydroxyapatite reinforced collagen scaffolds seeded with human adipose-derived stem cells

Mineral deposition and vascular invasion of hydroxyapatite reinforced collagen scaffolds seeded with human adipose-derived stem cells

... for bone tissue engin- eering because they mimic the key components of bone, collagen and mineral, and possess improved mechanical properties compared to either component alone [4, ...

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Vertical ridge augmentation using a porous composite of uncalcined hydroxyapatite and poly-DL-lactide enriched with types 1 and 3 collagen

Vertical ridge augmentation using a porous composite of uncalcined hydroxyapatite and poly-DL-lactide enriched with types 1 and 3 collagen

... formed bone was demonstrated histologically in both the experimental and the control ...formed bone in direct contact with the surface of the ...host bone. The newly formed bone had ...

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Mechanisms and functions of collagen glycosylations in bone

Mechanisms and functions of collagen glycosylations in bone

... In addition, mutations in PLOD1 were also found in patients affected with Nevo syndrome, a rare, autosomal recessive disorder with clinical features similar to those of EDS VIA (90). Plod1 null mice, recently generated, ...

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Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow derived mesenchymal stem cells and articular chondrocytes

Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow derived mesenchymal stem cells and articular chondrocytes

... OAB bone tissue and cells that might modulate the chondrogenic phenotype of BMSC is not comprehensively ...subchondral bone from OA-affected joints on chondrogenic differentiation of human BMSC derived from ...

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The biochemistry of metabolic bone disease: Investigation and experimental treatment

The biochemistry of metabolic bone disease: Investigation and experimental treatment

... measured bone formation (but not resorption) and with isotopic measurements of bone turnover in normal individuals and in post-menopausal osteoporosis and hyperparathyroidism (Brown et a l, 1984; Charles et ...

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Endochondral bone formation in toothless (osteopetrotic) rats: failures of chondrocyte patterning and type X collagen expression

Endochondral bone formation in toothless (osteopetrotic) rats: failures of chondrocyte patterning and type X collagen expression

... endochondral bone growth is cell division and hypertrophy of ...of collagen types II and X, are arranged in arrays across the growth ...in collagen II and X genes as well as the absence of their gene ...

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Trabecular bone loss in collagen antibody induced arthritis

Trabecular bone loss in collagen antibody induced arthritis

... generalized bone loss in CAIA ...and bone measurement were performed with peripheral quantitative computer tom- ography ...generalized bone loss, and this technique has also previously been ...

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The trans-well coculture of human synovial mesenchymal stem cells with chondrocytes leads to self-organization, chondrogenic differentiation, and secretion of TGFβ

The trans-well coculture of human synovial mesenchymal stem cells with chondrocytes leads to self-organization, chondrogenic differentiation, and secretion of TGFβ

... of bone marrow-derived mesenchymal stem cells (BMSC) in osteoarthritic knees resulted in a long-term improvement of clinical outcome parameters [3], and SMSC were successfully used for arthroscopically assisted ...

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Effectiveness of Xenograft and Porcine-Derived Resorbable Membrane in Augmentation of Posterior Extraction Sockets with a Severe Wall Defect. A Radiographic/Tomographic Evaluation

Effectiveness of Xenograft and Porcine-Derived Resorbable Membrane in Augmentation of Posterior Extraction Sockets with a Severe Wall Defect. A Radiographic/Tomographic Evaluation

... formed bone of ...and bone-to-implant contact ...xenogenic bone depends on the processing that can cause variations in physicochemical properties, hydrophilicity, and viscoelasticity of the material ...

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Study of human like collagen adsorption on true bone ceramic

Study of human like collagen adsorption on true bone ceramic

... the bone was placed in a furnace, and the temperature was increased to 700 °C at a heating rate of 5 °C/min and maintained for 3 h, and then cooling with the ...The bone was then immersed in ...

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The inhibitory effects of a RANKL binding peptide on articular and periarticular bone loss in a murine model of collagen induced arthritis: a bone histomorphometric study

The inhibitory effects of a RANKL binding peptide on articular and periarticular bone loss in a murine model of collagen induced arthritis: a bone histomorphometric study

... and bone resorp- tion [13, ...promote bone for- mation, as well as to inhibit bone resorption ...promote bone formation was de- creased in osteoblasts isolated from RANKL-deficient mice ...

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Collagen-grafted porous HDPE/PEAA scaffolds for bone reconstruction

Collagen-grafted porous HDPE/PEAA scaffolds for bone reconstruction

... For bone reconstruction such as skull base reconstruc- tion after tumor resection, an interconnected porous structure is critical to mimicking the bone extracellular matrix ...porous bone scaffolds ...

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Characterization of the Interaction Between Bone Sialoprotein and Type I Collagen

Characterization of the Interaction Between Bone Sialoprotein and Type I Collagen

... on collagen, future studies will be important to fully elucidate this domain and to determine how this interaction promotes nucleation of ...on collagen could involve the use of the biotinylated rBSP ...

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The role of biomarkers in the management of bone-homing malignancies

The role of biomarkers in the management of bone-homing malignancies

... In a recent proteomic analysis, performed on MDA-MB-231 sub- populations with variable organotropism, macrophage-capping protein (CAPG) and PDZ domain–containing protein member 1 (GIPC1) were up-regulated in ...

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