Bone development and metabolism
Role of Nrf2 in bone metabolism
... embryonic bone development and postnatal osteoblastic function ...intramembranous bone formation is almost completely suppressed in mice defi- cient for Runx2, and chondrocyte maturation is arrested ...
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Proteomics approaches for the studies of bone metabolism
... from bone tissues, have high heterogeneity, and there is still limitation for the LC-MS/MS technology to detect the low abundant proteins, current elucidation of complex mechanisms during skeletogenesis in vivo by ...
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Vitamin D metabolism in human pregnancy with an emphasis on the placenta and bone metabolism
... of bone metabolism appear to be inconsistent with two recent randomized controlled trials (42,43) which demonstrated no effects of maternal vitamin D3 supplementation (1,000 IU/d (43) and 200 IU/d (42)) on ...
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An essential role for IGF2 in cartilage development and glucose metabolism during postnatal long bone growth
... postnatal bone development, which involves proper timing of chondrocyte maturation and perichondrial cell differentiation and ...glucose metabolism in the Igf2 null ...
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Regulation of Bone Metabolism
... a bone-derived phosphaturic hormone and a member of the FGF19 subfamily, which is expressed in osteoblasts/osteocytes in response to phosphate and vitamin D (35, 45, ...for bone homeostasis and ...and ...
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The Effects of Adiponectin on Bone Metabolism
... 3. Bone Remodeling Bone remodeling is a continuous process throughout adult life consisting of the resorption of senescent bone Figure ...and development of obesity-related disease, such as ...
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Physiology of Bone Formation, Remodeling, and Metabolism
... Normal bone remodeling cycle requires that the process of bone resorption and bone forma- tion take place in a coordinated fashion, which in turn depends on the orderly development and ...
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Sclerostin : a key regulator of bone metabolism
... osteoblast development and inhibits their activity and reduces their life-span ...excessive bone formation which, however, decreases considerably when this pool is reduced, as occurs in ...of bone ...
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The influence of thyroid dysfunction on bone metabolism
... normal development and function of human ...if bone changes observed in state of thyrotoxi- cosis are related to lack of TSH or to excess of thyroid hormones or both of ...on bone metabolism ...
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Parameters Of Bone Tissue Metabolism In Women With Rheumatoid Arthritis
... in bone mass and micro- architectural violation of bone tissue, resulting in an increased risk of fractures and deсline in the quality of life of ...in bone mineral density is not only formed locally ...
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Diabetes Mellitus Related Bone Metabolism and Periodontal Disease
... Oxidative stress Oxidative stress is central to the development of insulin resistance and diabetic complications. 33–34 Oxidative stress plays a critical role in diabetic complications. Hyperglycemia leads to the ...
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Obesity and Bone Metabolism
... favourable bone microarchitecture and greater bone strength than adults with a normal BMI, associated with lower bone turnover which might be driven by the effects of greater leptin and E2 in ...
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CALCIUM METABOLISM OF BONE IN VITRO INFLUENCE OF BONE CELLULAR METABOLISM AND PARATHYROID HORMONE
... concentration at 2 hours between living and heat- inactivated samples (Figure 1) suggests that in both experiments the reduction was the result of cessation of cellular metabolism rather[r] ...
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Antiepileptic drugs and bone metabolism
... these bone effects and are potentially treatable ...with bone loss and needs to be considered in the management of bone dis- ease associated with ...on bone, there appears to be a general lack ...
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Effects of obesity on bone metabolism
... to bone mass. To our knowledge, obesity possibly affects bone metabolism through several ...and bone resorption through modifying the receptor activator of NF- B (RANK)/RANK ...
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The Effects of Warfarin on Bone Metabolism
... on Bone Metabolism Introduction Bone is a metabolically active organ which has a permanent renewal in the life ...the bone as a reservoir for calcium, phosphate, and magnesium ...
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The Role of Claudins in Bone Metabolism
... of bone mineral density variation, as evident from twins and family studies that suggest a high (50-85%) heritability of bone mineral density (Arden, Baker, Hogg, Baan, & Spector, 1996; Smith, Nance, ...
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Review Article Transdifferentiation between bone and fat on bone metabolism
... of bone and fat is a new insight in studying the increasingly bone marrow fat in the process of osteoporosis of elderly or menopause crowd which is increasing in ...of bone mass in osteoporosis is ...
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5. Calcium metabolism & bone physiology.pptx
... the bone where it mobilizes Ca ++/ PO4 -3 by increasing the active transport of Ca +2 out of osteoblasts in to ...new bone fails to mineralize because of ...
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Drugs affecting calcium and bone metabolism
... inhibits bone resorption and stimulates bone formation - Mechanism (?): stroncium is similar to calcium, absorbed on the hydroxyapatite crystals, exchanged to calcium in the bone minerals and remain ...
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