Bone marrow derived macrophage (BMDM)
Original Article Effect of rTsP53 on the M1/M2 activation of bone-marrow derived macrophage in vitro
... sepsis, macrophage can directly phagocytose pathogenic microor- ganisms, directly causing damage to a variety of pathogenic microorganisms by enzymes and bioactive substances generated itself, and can also change ...
16
M2 bone marrow-derived macrophage-derived exosomes shuffle microRNA-21 to accelerate immune escape of glioma by modulating PEG3
... ments. BMDM-Exos was obtained by ultra-high speed centrifugation and then was ...identified. BMDM-Exos was co- cultured with U87 cells to detect the biological ...
17
Aging impairs peritoneal but not bone marrow derived macrophage phagocytosis
... Bone marrow progenitors, differentiated in vitro, showed no age- related defect in macrophage phagocytosis ...the bone marrow environment in old mice could impact on macrophage ...
10
Evaluation of polarising stimuli on bone marrow derived macrophage phenotypes in two models of neuroinflammation
... It has been acknowledged for over a decade that macrophages adopt different phenotypes in response to different stimuli. In the past few years, it has become apparent that macrophages infiltrate the brain under certain ...
182
Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts
... 1; BMDM: bone marrow‑derived macrophage; C4HSU: control helper‑dependent adenoviral vector; cDNA: complementary deoxyribonucleic acid; C/EBP: CAAT enhancer binding protein; COX‑2: ...
12
The immune suppressive microenvironment of human gliomas depends on the accumulation of bone marrow-derived macrophages in the center of the lesion
... and BMDM in each layer ...of BMDM and MG, we performed an un- supervised T-Distributed Stochastic Neighbor Embedding (t-SNE) analysis by combining all these parameters, and we obtained the clusterization of ...
14
New application of anti-TLR monoclonal antibodies: detection, inhibition and protection
... BM-cDC: bone marrow-derived conventional dendritic cell; BM-MC: bone marrow-derived macrophage; BM-pDC: bone marrow-derived plasmacytoid dendritic ...
8
Aging, inflammation, stem cells, and bone healing
... In addition to intrinsic changes of aging, macrophages are modulated by their aging microenvironment and a poorly described number of external factors. When challenging young macrophages with aged serum, Gomez et al. ...
7
Anti osteoclastogenic activity of matairesinol via suppression of p38/ERK NFATc1 signaling axis
... mouse bone marrow-derived macrophage cells (BMMs) were cultured for 4 days in the presence of RANKL and M-CSF with the vehicle (DMSO) or ...
8
Macrophage phenotype in response to ECM bioscaffolds
... pro-inflammatory macrophage phenotype has been associated with the therapeutic use of bioscaffolds composed of extracellular matrix (ECM), but phenotypic characterization of macrophages has typically been limited ...
37
Mast cell–derived angiopoietin 1 plays a critical role in the growth of plasma cell tumors
... ng/ml). Bone marrow mast cells, obtained from C57BL/6 mice (National Cancer Institute), were cultured with 10 ng/ml IL-3 (these are referred to here as BMMCs) or with 100 ng/ml SCF plus 50 ng/ml IL-6 plus ...
10
Role of the IL-33-ST2 axis in sepsis
... BMDMs: Bone marrow-derived macrophages; CLP: Cecal ligation and puncture; DAMPs: Danger-associated molecular patterns; DCs: Dendritic cells; GMC- SF: Granulocyte macrophage colony-stimulating ...
9
IL-15 Generates IFN-γ-producing Cells Reciprocally Expressing Lymphoid-Myeloid Markers during Dendritic Cell Differentiation
... BM: bone marrow; BMDCs: bone marrow-derived dendritic cells; BMDMs: bone marrow-derived macrophages; CD: cluster of differentiation; CFU: colony-forming unit; DCs: ...
17
Role of whole bone marrow, whole bone marrow cultured cells, and mesenchymal stem cells in chronic wound healing
... Mesenchymal stem cells were generated according to the protocol described by Stem Cell Technologies Inc. Cat No 28453. These methods do not support the long- term growth of hematopoietic stem and progenitor cells. WBM ...
11
Current Concepts in Bone Graft Substitutes
... Autogenous bone grafts retain their viability for 2 h when kept in normal saline ...new bone growth to fill the defect even after autoclaving, but freeze-drying of autogenous bone did not alter the ...
16
The Current Perspectives of Stem Cell Therapy in Orthopedic Surgery
... Stem cells are described as to have a potential to dif- ferentiate more than 200 different cell types in the body. They are specific cell types that can create new cells in exist- ing healthy tissues and may help to ...
8
Role of Bone Marrow-Derived Mesenchymal Stem Cells Differentiate into β Cells in the Pancreatic Microenvironment
... BM-MSCs have exhibited a surprising capacity to differentiate into various ectoderm, mesoderm and endoderm-derived cells [7], and contribute to the formation of tissues. It has been shown that BM-MSCs can ...
14
Intramuscular injection of human umbilical cord-derived mesenchymal stem cells improves cardiac function in dilated cardiomyopathy rats
... Adult male Sprague-Dawley rats (average body weight 180 ± 20 g) purchased from Shandong Lukang Pharma- ceutical (Jining, Shandong, China) were caged and main- tained in an SPF-grade animal facility at the Affiliated ...
10
Autologous bone marrow cell therapy for peripheral arterial disease
... The average follow-up of these clinical studies was 8.4 ± 9.55 months. Considering all studies, the reported outcomes for therapeutic efficacy of cell therapy involved the ankle-brachial index, TcPO 2 , LDF, pain-free ...
10
Meniscus repair using mesenchymal stem cells – a comprehensive review
... study where 22.4 million precultured autologous MSCs along with 1 ml nucleated cells (isolated from fresh bone) and 1 ml 10% v/v platelet lysate were intra-articularly injected into a 46-year-old male patient ...
10