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bone marrow-derived MSCs

Mesenchymal stem cell therapy for osteoarthritis: current perspectives

Mesenchymal stem cell therapy for osteoarthritis: current perspectives

... conditions, bone marrow may be impacted to the greatest ...on bone marrow-derived MSCs, with adipose-derived MSCs maintain- ing a greater level of ...

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Placental mesenchymal stem cells of fetal and maternal origins demonstrate different therapeutic potentials

Placental mesenchymal stem cells of fetal and maternal origins demonstrate different therapeutic potentials

... by MSCs in high levels under inflamma- tion conditions but not under normal physical condi- tions ...the MSCs are used for cell ...decreased bone morphogenetic protein (BMP)-induced osteoblast activ- ...

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Characterization, recellularization, and transplantation of rat decellularized testis scaffold with bone marrow-derived mesenchymal stem cells

Characterization, recellularization, and transplantation of rat decellularized testis scaffold with bone marrow-derived mesenchymal stem cells

... passage, bone marrow-derived MSCs were harvested and loaded at a density of 5 × 10 4 per each scaffold for 24, 48, and 72 ...of MSCs was seeded in a 2D conventional condition as the ...

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Regeneration of a full-thickness defect of rotator cuff tendon with freshly thawed umbilical cord-derived mesenchymal stem cells in a rat model

Regeneration of a full-thickness defect of rotator cuff tendon with freshly thawed umbilical cord-derived mesenchymal stem cells in a rat model

... [6]. Bone marrow-derived MSCs (BM MSCs) and adipose tissue-derived MSCs (AD MSCs) improve collagen organization and collagen fiber coherence and enhance the tensile ...

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The expression of cytochrome P4502J2 gene and 14, 15 epoxyeicosatrienoic acid level influence the amount of insulin secreted from human mesenchymal stem cell-derived insulin-producing cells

The expression of cytochrome P4502J2 gene and 14, 15 epoxyeicosatrienoic acid level influence the amount of insulin secreted from human mesenchymal stem cell-derived insulin-producing cells

... and bone marrow (Vanella et ...conditions, bone marrow-derived MSCs (BM-MSCs) can be differentiated into insulin-producing cells ...

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Optimization of adipose tissue-derived mesenchymal stem cells by rapamycin in a murine model of acute graft-versus-host disease

Optimization of adipose tissue-derived mesenchymal stem cells by rapamycin in a murine model of acute graft-versus-host disease

... aGVHD. MSCs can decrease GVHD when co-transplanted with hematopoietic stem cells ...of bone marrow-derived MSCs (BM-MSCs) that were isolated from the haploidentical donor, ...

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Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway

Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway

... MSC- derived exosomes in wound healing are promotion of cell proliferation, migration, differentiation, angiogenesis, and matrix reconstruction ...that MSCs exert their therapeutic effect via secretion of ...

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Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells

Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells

... BM-MSCs: Bone marrow- derived mesenchymal stem cells; CT: Culture time; CPD: Cumulative population doubling; EC-MSCs: Equine cadaver mesenchymal stem cells; DMSO: Dimethyl sulfoxide; ...

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Adipose Tissue and Bone Marrow-Derived Mesenchymal Stem Cells Role in Regeneration of Cleft Alveolus in Dogs

Adipose Tissue and Bone Marrow-Derived Mesenchymal Stem Cells Role in Regeneration of Cleft Alveolus in Dogs

... of bone defects as cleft alveolus remains a clinical challenge. Bone tissue engineering is considered as a promising substitute to bone grafting, autogenous and allogenic grafting ...Highest ...

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Abstract: Mesenchymal Stem Cells derived from bone marrow (hBM-MSCs) are utilized in tendon

Abstract: Mesenchymal Stem Cells derived from bone marrow (hBM-MSCs) are utilized in tendon

... Taking these indications into account, the same treatment was imparted on hWJ-MSCs which showed several similarities but also some differences. First, given their faster population doubling levels (Figure 2) [44], ...

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Characterization of menstrual stem cells: angiogenic effect, migration and hematopoietic stem cell support in comparison with bone marrow mesenchymal stem cells

Characterization of menstrual stem cells: angiogenic effect, migration and hematopoietic stem cell support in comparison with bone marrow mesenchymal stem cells

... MenSCs derived from multiple donors using a large battery of markers, aiming not only for typical mesen- chymal and embryonic markers but also for endothelial and epithelial lineage markers, since these cell types ...

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Galectin-3 mediates bone marrow microenvironment-induced drug resistance in acute leukemia cells via Wnt/β-catenin signaling pathway

Galectin-3 mediates bone marrow microenvironment-induced drug resistance in acute leukemia cells via Wnt/β-catenin signaling pathway

... Figure 5 Gal-3 up-regulation promotes phosphorylation of Akt and GSK-3 β , thereby supporting β -catenin stabilization. (A) The protein level of phosphorylated Akt (Pho-Akt), total Akt (T-Akt), phosphorylated GSK-3 β ...

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Tissue-derived mesenchymal stromal cells used as vehicles for anti-tumor therapy exert different in vivoeffects on migration capacity and tumor growth

Tissue-derived mesenchymal stromal cells used as vehicles for anti-tumor therapy exert different in vivoeffects on migration capacity and tumor growth

... of bone marrow [10,11], and since then, they have been isolated from a wide variety of adult [12-20] and fetal (both first and second trimester) tissues, including blood, liver, bone marrow, ...

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Study on chemotaxis and chemokinesis of bone marrow-derived mesenchymal stem cells in hydrogel-based 3D microfluidic devices

Study on chemotaxis and chemokinesis of bone marrow-derived mesenchymal stem cells in hydrogel-based 3D microfluidic devices

... of MSCs, MSC migration in three dimensional environments remains largely ...human MSCs in the presence of stromal-cell derived factor-1 α (SDF-1 α ), interleukin 8 (IL-8) and Substance P (SP) which ...

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Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial

Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial

... using bone marrow or adipose-derived stem cells [33, 70–77], many of which are case reports [70, 74, 75, ...the bone heal- ing is dependent on the location of the defected ...induce ...

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Nascent osteoblast matrix inhibits osteogenesis of human mesenchymal stem cells in vitro

Nascent osteoblast matrix inhibits osteogenesis of human mesenchymal stem cells in vitro

... demineralized bone matrix (DBM) because of their activity in inducing bone forma- tion ...enhance bone formation (e.g., collagen type I [21]), the reactivity of MSCs to na- tive OB matrix, ...

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Review Paper: Embryonic Stem Cell and Osteogenic Differentiation

Review Paper: Embryonic Stem Cell and Osteogenic Differentiation

... biological bone substitutes that re- store, maintain, or improve bone tissue ...for bone tissue engineering [1] (Figure ...(ESCs), bone marrow (BM)-de- rived or umbilical cord blood ...

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Mesenchymal Stromal Cells Derived from Human Embryonic Stem Cells, Fetal Limb and Bone Marrow Share a Common Phenotype but Are Transcriptionally and Biologically Different

Mesenchymal Stromal Cells Derived from Human Embryonic Stem Cells, Fetal Limb and Bone Marrow Share a Common Phenotype but Are Transcriptionally and Biologically Different

... of MSCs from three ontogenically different sources: human embryonic stem cells, fetal limb and bone ...marrow. MSCs are also known for their ability to secrete paracrine factors that promote ...

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Repair of Spinal Cord Injury; Mesenchymal Stem Cells as an Alternative for Schwann Cells

Repair of Spinal Cord Injury; Mesenchymal Stem Cells as an Alternative for Schwann Cells

... Bone marrow and adipose-derived stem cells (ADSCs) as mesenchymal stem cells (MSCs), which also derived from peripheral blood, placenta and umbilical cord, the lung, and the heart, are ...

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Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta

Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta

... differentiated MSCs were then collected, and the endothelial gene expression further comparatively ...EC-differentiated MSCs in comparison with undiffer- entiated cells; however, no statistical significance ...

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