Bovine Leukemia Virus
Polyclonal bovine sera but not virus-neutralizing monoclonal antibodies block bovine leukemia virus (BLV) gp51 binding to recombinant BLV receptor BLVRcp1.
... Bovine leukemia virus (BLV) is a lymphotropic retrovirus of cattle that is closely related to human T-cell lymphotropic viruses 1 and 2 and causes enzootic lymphosarcoma/leukemia in a small ...
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Even Attenuated Bovine Leukemia Virus Proviruses Can Be Pathogenic in Sheep
... the virus. Bovine leukemia virus (BLV) replication occurs via two main processes: the infection of new cellular targets and the mitosis of the host cell (recently reviewed in references 7 and ...
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Assessment of Bovine Leukemia Virus Transcripts In Vivo
... Bovine leukemia virus (BLV), a B-cell lymphotropic retro- virus of the BLV–human T-cell leukemia virus (HTLV) genus, causes a persistent B-lymphocytosis (PL) and/or a neoplastic ...
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In vivo infection of sheep by bovine leukemia virus mutants.
... 4078-4085 0022-538X/93/074078-08$02.00/0 Copyright © 1993, American Society for Microbiology JOURNAL OF VIROLOGY, In Vivo Infection of Sheep by Bovine Leukemia Virus Mutants LUC WILLEMS,[r] ...
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Experiments with cloned complete tumor-derived bovine leukemia virus information prove that the virus is totally exogenous to its target animal species.
... 2 Experiments with Cloned Complete Tumor-Derived Bovine Leukemia Virus Information Prove that the Virus Is Totally Exogenous to Its Target Animal Species Received 24 March 1981/Accepted [r] ...
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Prevalence of bovine leukemia virus (BLV) infection in the northeast of Iran
... The purpose of this study was to determine the prevalence of bovine leukemia virus (BLV) in Khorasan Razavi and Khorasan Shomali provinces which are the main provinces located in the northeast of ...
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T-cell responses to highly conserved CD4 and CD8 epitopes on the outer membrane protein of bovine leukemia virus: relevance to vaccine development.
... Protection of sheep against bovine leukemia virus BLV infection by vaccination with recombinant vaccinia viruses expressing BLV envelope glycoproteins: correlation of protection with CD4[r] ...
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Molecular cloning of covalently closed circular DNA of bovine leukemia virus.
... Comprehensive restriction endonuclease mapping of the unintegrated bovine leukemia virus and the cloned DNA molecules showed that eight of the nine clones carried viral information witho[r] ...
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Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection
... for bovine Tim-3 and Gal-9 were cloned and sequenced, and their expression and role in immune reactivation were analyzed in bovine leukemia virus (BLV)-infected ...that bovine Tim-3 ...
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Bovine leukemia virus discovered in human blood
... cies: bovine leukemia virus and Homo sapiens, and to insure that the primers we used were detecting only bovine leukemia virus and not other retroviruses or the human genome, ...
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Molecular characterization of bovine leukemia virus reveals existence of genotype 4 in Chinese dairy cattle
... Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leucosis (EBL), and approximately 30% of infected cattle develop persistent lymphocyto- sis (PL) while a small percentage ...
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Bovine leukemia virus long terminal repeat variability: identification of single nucleotide polymorphisms in regulatory sequences
... Bovine leukemia virus (BLV) is the etiological agent of enzootic bovine leucosis (EBL), a chronic, lymphopro- liferative disease associated with persistent lymphocy- tosis and B-cell ...T-cell ...
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Epidemiology and genetic diversity of bovine leukemia virus
... Bovine leukemia virus (BLV), an oncogenic member of the Deltaretrovirus genus, is closely related to human T-cell leukemia virus (HTLV-I and ...
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Bovine Leukemia Virus Structural Gene Vectors Are Immunogenic and Lack Pathogenicity in a Rabbit Model
... replication-competent bovine leukemia virus structural gene vector (BLV SGV) is an innovative vaccination approach to prevent disease by complex ...SGV virus is replication competent and ...
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Early Syncytium Formation by Bovine Leukemia Virus
... In fact, when cell densities of 4 x 105 cells per 2.1 cm2 or greater are used, discrete syncytia are very difficult to observe even after 24 to 48 h Downloaded from http://jvi.asm.org/ o[r] ...
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Identification and characterization of common B cell epitope in bovine leukemia virus via high throughput peptide screening system in infected cattle
... cinia virus expressing Env vaccine had reduced the pro- viral load in vaccinated sheep used as an experimental model, nonetheless it had not effected in cows [43, ...
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Construction of a recombinant bovine leukemia virus vector for analysis of virus infectivity.
... In an attempt to determine whether cells transfected with pBLV913 are able to produce infectious virus, the plasmid was transfected into the human cell line RD-4 in combination with a ta[r] ...
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Expression of the bovine leukemia virus X region in virus-infected cells.
... Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene.. Identification of the putative transforming prot[r] ...
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Suppression of Viral Gene Expression in Bovine Leukemia Virus-Associated B-Cell Malignancy: Interplay of Epigenetic Modifications Leading to Chromatin with a Repressive Histone Code
... Epigenetic mechanisms such as DNA methylation are tightly connected to cancer. It is well documented that oncogenesis is promoted by local hypermethylation of tumor suppressor genes (7, 41). Here, local hypermethylation ...
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Lower mutation rate of bovine leukemia virus relative to that of spleen necrosis virus.
... Virus was harvested from Step 2 clones and was used to infect fresh FLK cells, which were then placed under G418 selection in the presence of os-BLV antiserum Step 3 cells.. Alternativel[r] ...
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