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Brain connectome

Disrupted topological organization of human brain connectome in diabetic retinopathy patients

<p>Disrupted topological organization of human brain connectome in diabetic retinopathy patients</p>

... Methods: Thirty- fi ve DR patients (18 males and 17 females) and 38 healthy controls (HCs) (18 males and 20 females), matched for age, sex, and education, underwent resting-state magnetic resonance imaging scans. Graph ...

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Adolescence is associated with genomically patterned consolidation of the hubs of the human brain connectome

Adolescence is associated with genomically patterned consolidation of the hubs of the human brain connectome

... that brain networks generally have complex to- pological properties, including hubs, modules, and rich clubs (39, ...structural brain connectome are disproportionately located in association cortex ...

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Computing the social brain connectome across systems and states

Computing the social brain connectome across systems and states

... disparate brain states, significant clusters-wise whole-brain connectivity was also assessed using resting-state correlations as an independent modality of functional ...all brain scans to the first ...

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The intrinsic geometry of the human brain connectome

The intrinsic geometry of the human brain connectome

... the brain are mapped near each ...of brain imag- ing as well ...of brain con- nectome after dimensionality reduction could be compared groupwise in disease states, and/or could be regressed with ...

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Evaluation of machine learning algorithms for treatment outcome prediction in patients with epilepsy based on structural connectome data

Evaluation of machine learning algorithms for treatment outcome prediction in patients with epilepsy based on structural connectome data

... structural brain connectome. Specifically, the brain connectome is reconstructed using white matter fiber tracts from presurgical diffusion tensor ...two-stage connectome-based ...

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Rich club disturbances of the human connectome from subjective cognitive decline to Alzheimer's disease

Rich club disturbances of the human connectome from subjective cognitive decline to Alzheimer's disease

... Previous graph theory studies found a decrease of strength and an increase of characteristic path length in preclinical AD, which was consistent with our results [25, 77]. In addition, in line with MCI and AD DTI network ...

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PubMedCentral-PMC5555750.pdf

PubMedCentral-PMC5555750.pdf

... static-but-attuned brain architecture has a fundamental role in conferring the benefits of shared and synchronized emotional experiences to some of the most important people in our social ...dyadic brain ...

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Neural and genetic determinants of creativity

Neural and genetic determinants of creativity

... whole-brain connectome (34,716 functional connectivities) and whole genome data (309,996 SNPs) in two datasets (all collected by Southwest University, Chongqing) consisting of altogether 236 subjects, for a ...

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Of what use is connectomics? A personal perspective on the Drosophila connectome

Of what use is connectomics? A personal perspective on the Drosophila connectome

... Knowledge of the fly connectome enables us to interpret functional interactions revealed either by imaging (e.g. Seelig et al., 2010; Akerboom et al., 2012; Simpson and Looger, 2018) or by electrophysiological ...

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PubMedCentral-PMC5619942.pdf

PubMedCentral-PMC5619942.pdf

... A connectome was built which describes how strongly inter- connected a given cortical or subcortical region is with all other ...whole connectome included mean strength (K), global efficiency (E), and mean ...

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Predicting Surgery Targets in Temporal Lobe Epilepsy through Structural Connectome Based Simulations

Predicting Surgery Targets in Temporal Lobe Epilepsy through Structural Connectome Based Simulations

... Connectome creation from the acquired data is summarised in Fig 6, while Fig 7 shows nodes and connections imaged in pseudo-3D space averaged over all subjects, and indicates how this is then used to generate ...

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A predictive model of the cat cortical connectome based on cytoarchitecture and distance

A predictive model of the cat cortical connectome based on cytoarchitecture and distance

... of brain connectivity and found neural wiring length to be of critical importance (Bullmore and Sporns ...However, brain connectivity does not appear to be exclusively opti- mized with respect to physical ...

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General features of the retinal connectome determine the computation of motion anticipation

General features of the retinal connectome determine the computation of motion anticipation

... The brain estimates the location of an object in visual space by reading out which retinal ganglion cells (RGCs) respond to it. This ‘retinotopic map’ is preserved through the visual pathway and is used to guide ...

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Advances in diffusion MRI acquisition and processing in the Human Connectome Project

Advances in diffusion MRI acquisition and processing in the Human Connectome Project

... These predictions can be combined with the already obtained susceptibility-induced off- resonance field, a model of eddy-current-induced off-resonance field (quadratic spatial model used for the HCP), and a model of ...

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Whole animal modeling: piecing together nematode locomotion

Whole animal modeling: piecing together nematode locomotion

... Rapidly growing computational power, tools, and re- sources are facilitating a step change in the generation and analysis of big data, including static networks, behavioral, and brain-wide imaging data, or high- ...

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A unique pattern of cortical connectivity characterizes patients with attention deficit disorders: a large electroencephalographic coherence study

A unique pattern of cortical connectivity characterizes patients with attention deficit disorders: a large electroencephalographic coherence study

... The connectome manifested decreased and increased ...coherence connectome differentiating ADD from CON subjects including subgroups with and without comorbidities and/or ...‘ connectome ’ , ...

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Tau burden and the functional connectome in Alzheimer's disease and progressive supranuclear palsy

Tau burden and the functional connectome in Alzheimer's disease and progressive supranuclear palsy

... A between-subject analysis assessed the second and third hypotheses. This was undertaken at a variety of spatial scales. We first looked across the whole brain. For each individual, we first calculated a measure of ...

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Novel and rare functional genomic variants in multiple autoimmune syndrome and Sjögren’s syndrome

Novel and rare functional genomic variants in multiple autoimmune syndrome and Sjögren’s syndrome

... It must also be noted that ICA1, coding for ICA69 autoantigen, has been previously associated with Diabe- tes mellitus type 1 (T1DM), based on cDNA expression analysis in islet cells [41], as well as being implicated in ...

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Automated processing pipeline for neonatal diffusion MRI in the developing Human Connectome Project

Automated processing pipeline for neonatal diffusion MRI in the developing Human Connectome Project

... Human Connectome Project is set to create and make available to the scientific community a 4- dimensional map of functional and structural cerebral connectivity from 20 to 44 weeks post-menstrual age, to allow ...

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A powerful and efficient multivariate approach for voxel level connectome wide association studies

A powerful and efficient multivariate approach for voxel level connectome wide association studies

... real connectome data have shown that sKPCR can accurately control the false- positive rate and that it is more powerful than many state-of-the-art approaches, such as the connectivity-wise generalized linear model ...

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