Breast Cancer (BC)
Next-generation sequencing in familial breast cancer patients from Lebanon
... individualized cancer therapy of Lebanese pa- tients with ...other breast cancer- associated genes, the clinical usefulness of the data is currently ...of breast cancer will remain ...
12
A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case control, population based study of African American women
... American Breast Cancer Epidemiology and Risk (AMBER) Consortium, genotyping and imputed data from four studies on BC in AA women were combined into a final dataset containing 224,188 miRNA gene ...
13
Decoding the usefulness of non coding RNAs as breast cancer markers
... of breast cancer (BC) have been recently accomplished, it still con- stitutes the leading cause of cancer death in women ...worldwide. BC is a heterogeneous and complex disease, making ...
15
Establishment and characterization of three new human breast cancer cell lines derived from Chinese breast cancer tissues
... three breast cancer cell lines had been proved to have severe tumorigenicity when injected into nude mice, and their tumorigenicity was higher than that of MCF-7 cell ...with BC-019 cells and ...
10
Application prospective of nanoprobes with MRI and FI dual-modality imaging on breast cancer stem cells in tumor
... into BC cells, which were probably used in biomedical diagnosis fields ...MCF-7 BC cells could be effectively tracked by FI and MRI in vitro ...human BC, and tracked BC in the lymphatic system ...
10
Locoregional recurrence-associated factors and risk-adapted postmastectomy radiotherapy for breast cancer staged in cT1-2N0-1 after neoadjuvant chemotherapy
... with BC staged in cT1-2N0-1M0 and treated with mastectomy after NAC in our institute between 2011 and 2013 were retrospectively ...and breast ultrasonography prior to chemo- ...bilateral breast ...
8
Serum concentrations of active tamoxifen metabolites predict long term survival in adjuvantly treated breast cancer patients
... of breast cancer [23 – ...in breast cancer patients with high serum metabolite ...and breast cancer outcome in patients receiving low doses of tamoxifen (1 mg, 5 mg, and 10 mg) ...
13
Topographic expression of the Hippo transducers TAZ and YAP in triple-negative breast cancer treated with neoadjuvant chemotherapy
... In breast cancer (BC), the activation of the TAZ/YAP- transcriptional program feeds a number of tumor- promoting functions ...with BC stem cells (BCSCs) [4, ...in BC is am- biguous, ...
8
Nanoparticle Delivery of miR-34a Eradicates Long-term-cultured Breast Cancer Stem Cells via Targeting C22ORF28 Directly
... HME, BC and BCSC had not been altered significantly after the corresponding transfection with Ctrl, TV-miR-Ctrl or TV-miR-34a, respectively (Figure ...parental breast cancer cells, as depicted in ...
20
Long non-coding RNAs: implications in targeted diagnoses, prognosis, and improved therapeutic strategies in human non- and triple-negative breast cancer
... (urothelial cancer associated 1, non-protein coding), which silence tumor suppressor ...in BC, regulat- ing genes involved in the EGFR/mammalian target of the rapamycin pathway and is required for cell ...
15
NEDD4 expression is associated with breast cancer progression and is predictive of a poor prognosis
... of BC, comprising approximately 60–75% of all breast carcinomas ...for BC develop- ment involves a sequential progression from hyperplasia, atypical ductal hyperplasia, ductal carcinoma in situ ...
16
Thymidylate synthase gene (TYMS) polymorphisms in sporadic and hereditary breast cancer
... Background: Breast cancer (BC) is a genetic disorder characterized by growth and proliferation of breast cells in a ...of BC, every year. The BC etiology is still poorly ...
6
Targeted Pten deletion plus p53 R270H mutation in mouse mammary epithelium induces aggressive claudin low and basal like breast cancer
... R270H, in mammary epithelium via WAP-Cre induces di- verse mammary tumor subtypes including PDA and spin- dle tumors. Intra- and inter-species cluster analysis classified most PDA and spindle tumors as basal-like and ...
16
Development of an exercise intervention for the prevention of musculoskeletal shoulder problems after breast cancer treatment: the prevention of shoulder problems trial (UK PROSPER)
... We are very grateful to experts who contributed to the Intervention Development Day hosted by the Warwick Clinical Trials Unit: Lizzie Fort, Catherine Hegarty, Lyn Ankcorn, Jocelyn Choyce, Alison Jelly, Wendy Leonard, ...
12
Couplelinks an online intervention for young women with breast cancer and their male partners: study protocol for a randomized controlled trial
... of Cancer Therapy-Breast (FACT-B) - Physical Well-Being (PWB) [105] subscale is part of the widely used FACT-B that assesses quality of life among breast cancer ...The Breast ...
15
Genetic risk variants associated with in situ breast cancer
... BC: breast cancer; BCAC: Breast Cancer Association Consortium; BCIS: breast cancer in situ; BMI: body mass index; BPC3: National Cancer Institute ’ s Breast ...
10
TSH receptor antibodies have predictive value for breast cancer – retrospective analysis
... and breast cancer was arguable and the results were summarized in Table 5 ...with breast cancer, with similar importance to the tumor size and to the axillary nodal status ...with ...
8
Clinicopathological and prognostic significance of Ras Association and Pleckstrin Homology domains 1 (RAPH1) in breast cancer
... in breast cancer using large annotated ...The Cancer Genome Atlas (TCGA) dataset (n=1039) and the results were validated using the Molecular Taxonomy of Breast Cancer International ...
29
Prolonged survival in patients with breast cancer and a history of brain metastases: results of a preplanned subgroup analysis from the randomized phase III BEACON trial
... No cytotoxic or molecularly targeted agent is approved for the treatment or prevention of BCBM [11, 12]. Molecular weight, lipophilicity, biodistribution, and drug efflux pumps all contribute to poor penetration of drugs ...
13
Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer
... The low prevalence of IBC, and the small size of diag- nostic biopsy specimens have been obstacles in under- standing of IBC pathogenesis. To date, current treatments are based on multimodal approaches, are non-specific ...
13