C-F bond activation
Selectivity of C-H activation and competition between C-H and C-F bond activation at fluorocarbons
... from C-H and C-F that dominates over the alternative where two C-H bonds have been activated (Scheme ...double C-H activation product is observed while if water is added the ...
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Utilising sodium-mediated ferration for regioselective functionalisation of fluoroarenes via C-H and C-F bond activations
... To conclude, by exploiting synergistic effects in sodium ferrate chemistry, we have unveiled a new regioselective method for the direct ferration of a wide range of fluoroarenes under mild reaction conditions as well as ...
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Enzyme-catalyzed C–F bond formation and cleavage
... The C–F bond is the strongest σ bond, and thus, it is difficult to cleave it under mild conditions (Goldman 1969; Lemal ...Enzyme-catalyzed C–F bond cleavage has attracted ...
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Organometallic chemistry using partially fluorinated benzenes
... Fluorobenzenes, in particular fluorobenzene (FB) and 1,2-difluorobenzene (1,2-DiFB), are increasingly becoming recognised as versatile solvents for conducting organometallic chemistry and transition-metal- based ...
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Stereochemical outcomes of C F activation reactions of benzyl fluoride
... benzylic C–F bond activation ...protic activation driven by the capacity of organic fluoride to form hydrogen bonds ...hydrogen bond donors have shown considerable success. This ...
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Activation of B-H, Si-H, and C-F bonds with Tp′Rh(PMe3) complexes : Kinetics, mechanism, and selectivity
... of bond is ...to C − H ...ecting C − H ...consider C − H functionalization reactions such as the conversion of methane to methanol because suitable methane activators react more rapidly with ...
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Tuning the Reactivity of Terminal Nickel(III)?Oxygen Adducts for C?H Bond Activation
... 8. (a) Hikichi, S.; Yoshizawa, M.; Sasakura, Y.; Akita, M.; Moro- oka, Y., J. Am. Chem. Soc. 1998, 120 , 10567-10568; (b) Itoh, S.; Bandoh, H.; Nagatomo, S.; Kitagawa, T.; Fukuzumi, S., J. Am. Chem. Soc. 1999, 121 , ...
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Iridium(I)-catalyzed regioselective C[BOND]H activation and hydrogen-isotope exchange of non-aromatic unsaturated functionality
... Dröge, F. Liu, F. Glorius, Chem. Soc. Rev. 2011, 40, 4740-4761; c) ...McMurray, F. O’Hara, M. J. Gaunt, Chem. Soc. Rev. 2011, 40, 1885-1898; f) ...
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C-C bond-forming reactions of ground-state aryl halides under reductive activation
... (b) Bud en, M. E.; Guastavino, J. F.; Rossi, R. A. Org. Lett. 2013, 15, 1174e1177; (c) Liu, W.; Tian, F.; Wang, X.; Yu, H.; Bi, Y. Chem. Commun. 2013, 2983e2985; (d) Kumar, A.; Bhakuni, B. S.; ...
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Driving forces for covalent assembly of porphyrins by selective C H bond activation and intermolecular coupling on a copper surface
... processes from other molecular sites with relatively low removal energies - like the 6-methyl groups and the βCH groups - and hence these events cannot be completely excluded. Assuming diffusion along the Cu rows and a ...
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Low coordinate iridium NHC complexes derived from selective and reversible C–H bond activation of fluoroarenes
... transition-metal-mediated C–H bond activation of partially fluorinated arenes is a potentially powerful means for accessing aryl fluoride synthons in organic chemistry, 1,2 providing an ortho- gonal ...
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Mechanistic study of Ru NHC catalyzed hydrodefluorination of fluoropyridines : the influence of the NHC on the regioselectivity of C–F activation and chemoselectivity of C–F versus C–H bond cleavage
... 5 F 4 HN as a minor product, but this species is then inert to any further ...of C 5 F 5 N is favored at the para-position and gives 2,3,5,6-C 5 F 4 HN as the major ...undergoes ...
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New approaches for C F bond formation in organic chemistry
... Both imidazolidinones show better enantiomeric excesses than the proline derivative catalysts with good yields (54 to 96%) and high enantioselectivities (91 to 99% ee). This method could be applied using a wide range of ...
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{[4 (4 [2,2′]Bipyridyl)phenyl]dimethylphosphine}dichloro(η5 pentamethylcyclopentadienyl)iridium(III)
... Therefore, it would be advantageous to attach a chromo- phore to an Ir-Cp* dihydride. Ef®cient energy transfer from the chromophore would activate the Ir-Cp* center. The title compound, (I), possesses a ...
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Dalton Discussion 12: Catalytic C–H and C–X Bond Activation91-97
... Suzuki-Miyaura cross-coupling over palladium nano- particles stabilised by polyvinylpyrrolidinone (PVP). This work, in collaboration with Professor Adam Lee, gave details about the reaction mechanism, including results ...
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Synthesis and Reactivity of Ruthenium Alkyl and Aryl Complexes and Their Application towards Aromatic C-H Bond Activation and Olefin Hydroarylation
... metal-mediated C-H activation step (see below) similar to that directly observed in stoichiometric aromatic C-H oxidative addition ...of C-H bonds to ethylene using 1 as catalyst is ...
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Biocatalyzed C-C bond formation for the production of alkaloids
... of C-C bonds in the alkaloid skeleton have been ...three C-C bond forming enzymes: two Pictet-Spenglerases and the oxidative C-C bond forming flavoenzyme Berberine ...
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Design, synthesis and biological evaluation of new substituted benzofuran-based derivatives via C−H bond activation
... hydrogen bond between ligand and enzyme is the most important, because in most cases it can decide the binding strength and the location of ligand, whereas the hydrophobic interaction of some certain groups can ...
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DEVELOPMENT OF COPPER APATITE CATALYST FOR C-C AND C-N BOND FORMATIONS
... Nitrogen containing heterocycles are found in numerous natural products and in many biologically active pharmaceuticals. N-arylimidazole derivatives have been reported to have biomedical applications, serving as cyclic ...
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3 Phenylpyrrolo[2,3 b]tropone
... The C—C bond lengths of the seven-membered ring show bond alternation typical of tropone; the C1—O1 bond length ...The C —C and C—N bond lengths in the ...
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