c-FLIP
ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells
... with c-FLIP to trigger c-FLIP ubiquitination and degradation, concomitantly with early ITCH recruitment to HER3 ...ITCH-induced c-FLIP degrad- ation after TNFα stimulation [26] ...
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Original Article Protective effect of RIP and c-FLIP in preventing liver cancer cell apoptosis induced by TRAIL
... and c-FLIP high expression were speculated to be the key fac- tor this ...and c-FLIP play an important function in TRAIL induced apoptosis through the RIP and c-FLIP gene ...
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Expression and biological significance of c-FLIP in human hepatocellular carcinomas
... TRAIL. c-FLIP has a more central role in the antiapoptotic NF-kB response than the TRAF/IAP ...hand, c-FLIP expression is regu- lated by NF-κB and phosphatidylinostiol-3 kinase (PI-3)/ Akt ...
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Original Article Impact of TILs on the prognosis of IIIB colon cancer associated with c-FLIP expression
... of c-FLIP L and the density of TILs in tumor tissues were examined through immunohistochemical ...of c-FLIP L and TILs, with the prognosis of patients was ...Results: C-FLIP L ...
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The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition
... exert c-Myc-independent activity [2, 6, ...increased c-Myc levels in H157 and A549 cells but decreased its levels in H1299 ...shows c-Myc upregulation by JQ1 in some lung cancer cell lines ...of ...
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E1A Sensitizes Cells to Tumor Necrosis Factor Alpha by Downregulating c-FLIPS
... formed with 5 mM manganese acetate. All reactions were done in triplicate. The threshold cycle represents the cycle at which an increase in fluorescence was statistically significant. The difference in one cycle value ...
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Multiple Functions of Cellular FLIP Are Essential for Replication of Hepatitis B Virus
... and C) Effect of c-FLIP knockdown on HBV replication and cccDNA level in HepG2-NTCP ...of c-FLIP knockdown on HBV replication in differentiated HepaRG ...after c-FLIP ...
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Iterative multi-channel radio frequency pulse calibration with improving B1 field uniformity in high field MRI
... The flip angle maps on an axial slice are shown in Figure 7a, b, c for the quadrature mode excitation, the iterative RF pulse calibration, and the B 1 shimming, ...The flip angle maps on a coronal ...
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Design and Analysis of Dual Edge Triggered (DET) Flip Flops Using Multiple C Elements
... DET flip- flops using simulation in the 180nm CMOS technology. The DET FLIP-FLOPS design and derivatives were shown significantly to consume the area related to previous works which improves process speed ...
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AN EFFICIENT IMPLEMENTATION OF GRAPHICAL CONVOLUTION TECHNIQUE USING SYNTHESIS TOOL FOR COMMUNICATION RELEVANCES
... To reset the register we have a clear input i.e., it clears all flip flops to 0. Register has another property to shift.. the data from one flip flop to another flip flop. That could be [r] ...
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RW-300_Theory_of_Operation_May59.pdf
... c (called dynamic) flip flops. pletion of the conversion, the status of each flip flop is shifted sequentially into a. sector on one of the analog input tracks on t[r] ...
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A Greedy Heuristic Algorithm for Flip-Flop Replacement Power Reduction in Digital Integrated Circuits
... of flip-flops in a chip increases dramatically the complexity would increase exponentially, which makes the method ...mergeable flip-flops transform the coordinate system of ...of flip-flops first ...
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Design of Sequential Circuits Using MV Gates in Nanotechnology
... JK flip flop can be considered as a refinement of the RS flip flop since the indeterminate state of the RS type is defined in the JK ...JK flip flop switches to its complement state, when inputs are ...
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Cells of the synovium in rheumatoid arthritis Synovial fibroblasts
... chemokines, C-X-C motif ligand (CXCL)2 (gro-2) and C-C motif ligand (CCL)8 (monocyte chemoattractant protein [MCP]-2) probably contribute significantly to the accumu- lation of inflammatory ...
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Performance Characteristics of the 10hp Induction Machine
... the flip-flop. This new family of flip-flops are called Embedded Logic Flip- ...logic flip-flop is shown in Fig. 1. Embedded Logic Flip-Flop(ELFF) are simple high speed low-power ...
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ALL OPTICAL 3-BIT SERIAL INPUT SHIFT REGISTER DESIGN
... In this paper, using analytical solutions of nonlinear effects in InGaAsP semiconductor optical amplifier, we have shown that with high input pump power generated conjugate pulses can be utilized to generate different ...
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animal weapon flip
... Hyatt and Salmon (1978) observed interspecifi c battles of the Atlantic Sand Fiddler Crab (Uca pugilator). Th ey defi ned each individual as either a “Resident” (one who currently has a burrow) or a “Wanderer” ...
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Design of a more Efficient and Effective Flip Flop to JK Flip Flop
... Logic equations (1a, 1b) & (1.1a, 1.2b) are derived from the K-Map and they can be used to construct the Flip Flop using the different gates as given by the equations. However, it is customary to use NOR and ...
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An Efficient D-Flip Flop Using Current Mode Signalling Scheme
... Fig 4 shows the current mode pulsed flip -flop with enabling architecture. This circuit uses an input current comparator stage, a register stage, and a static storage cell. The current comparator stage compares ...
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Design and Implementation of Four Level Asynchronous Counter Using D-Flipflop
... D flip-flop with preset and clear is designed this quaternary D flip-flop is compared to previously designed binary and multi-valued D ...D flip-flop is better than all other flip-flops ...
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