C-type lectin receptors
C-type lectin receptors and RIG-I-like receptors: new points on the oncogenomics map
... recognition receptors includes families of Toll-like receptors, NOD-like receptors, C-type lectin receptors, and RIG-I-like ...these receptors and proteins and ...
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Myeloid dendritic cells display downregulation of C type lectin receptors and aberrant lectin uptake in systemic lupus erythematosus
... phagocytic receptors and upregulation of antigen-presenta- tion machinery, and migration to lymphoid tissues to trigger secondary specific immune ...nition receptors, which recognize specific molecular ...
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<p>NOD1/2 and the C-Type Lectin Receptors Dectin-1 and Mincle Synergistically Enhance Proinflammatory Reactions Both In Vitro and In Vivo</p>
... It was previously demonstrated that combined stimula- tion of TLR2, TLR4, or TLR9 combined with NOD1 or NOD2 signi fi cantly enhances production of IL-8 in cul- tured THP-1 cells. 16 Herein, we evaluated whether produc- ...
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Chemoenzymatic Synthesis of N-glycan Positional Isomers and Evidence for Branch Selective Binding by Monoclonal Antibodies and Human C-type Lectin Receptors
... 2, with compound 2 presenting an additional benzyl group at C2 of the central mannose residue. The synthesis of both sca ff olds 1 and 2 42 follows a [3 + 2 + 2] building block approach and is described in detail in the ...
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Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors
... and receptors such as MHC1 and b1 integrins via steric occlusion, referred to as the ‘‘glycan umbrella’’ effect ...MBL receptors to enter cells with or without engaging EBOV-specific ...potential ...
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Targeting CLL-1 for acute myeloid leukemia therapy
... other c-type lectin receptors, DACL-2/ CLL-1 is mainly expressed on myeloid DC, it can be used as Ag capture receptor due to its internalization after lig- and binding and it can also interact ...
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Mutated Von Hippel-Lindau-renal cell carcinoma (RCC) promotes patients specific natural killer (NK) cytotoxicity
... activating receptors: human activating receptors comprise the natural cytotoxicity receptors (NCRs: NKp46, NKp30, and NKp44), C-type lectin receptors (CD94/NKG2C, NKG2D, ...
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Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets
... to C-type lectin receptors (CLRs) such as DC-SIGN expressed by human dermal DCs and Langerin expressed by Langerhans cells (LCs), which facilitate endocytosis and processing for antigen ...
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Immune-related Lectin-like Receptors in Zebrafish Innate Immunity
... recognition sites, and co-injected with the I-SceI meganuclease enzyme into zebrafish embryos at the one cell stage. The injected embryos were evaluated for GFP expression to select germline transmitting founder ...
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Lectin Glycan Interaction Network Based Identification of Host Receptors of Microbial Pathogenic Adhesins
... Candidiasis is a fungal infection caused by the adhesion of Candida yeast species to host cells. Candida albicans and C. glabrata are commensal yeasts of the human gastrointestinal tract, but they are also the ...
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The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus
... specific receptors that mediate IAV entry have not been defined and multiple receptors may ...the C-type lectin receptor langerin in Lec2 cells (Lec2-Lg) rendered them permissive to IAV ...
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mosGCTL-7, a C-Type Lectin Protein, Mediates Japanese Encephalitis Virus Infection in Mosquitoes
... recognition receptors (PRRs) that are involved in the induction of innate immunity gene expression in response to pathogen invasion in vertebrates (16, ...specific C-type lectin 1 (mosGCTL-1) ...
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Macrophage Receptors for Influenza A Virus: Role of the Macrophage Galactose-Type Lectin and Mannose Receptor in Viral Entry
... cellular receptors involved in infection of M by influenza virus and extends our previous study that impli- cated the MMR in this process ...surface C-type lectin, MGL, was demonstrated, ...
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Composition, Structure, Dynamics and Function of C-Type Lectin Receptor Domains
... membrane receptors in cell ...of receptors? Second, what other components reside in the DC-SIGN and CD206 nanodomains and how are these nanodomains stabilized? For DC-SIGN, these questions are particularly ...
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Tumor therapy in mice via antigen targeting to a novel, DC restricted C type lectin
... face receptors that mediate endocytosis of bound ...Possible receptors include ones shared by DCs and other cell types, such as the macrophage mannose receptor or the Fcγ receptors, as well as others ...
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The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120
... For some time, only three broadly neutralizing MAbs to HIV-1 were known (5, 12). Two of these MAbs bind to the surface glycoprotein, gp120, which is the viral receptor for CD4 and chemokine receptors CCR5 and ...
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Identification and Characterization of a Spliced C-Type Lectin-Like Gene Encoded by Rat Cytomegalovirus
... Cytomegaloviruses belong to the betaherpesvirus family, whose members exhibit characteristic species specificity and sal- ivary gland tropism (33). They generally cause a benign infec- tion and dwell permanently in the ...
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The Structure of the Poxvirus A33 Protein Reveals a Dimer of Unique C-Type Lectin-Like Domains
... A33 expression and purification. We expressed several A33 proteins that differed in their N termini but extended to the full-length C terminus at residue 185. The first A33 length variant encoded residues 82 to ...
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Hemagglutinating activity of Chickpea extracts for lectin
... study, lectin from desi chickpea (Cicer arietinum ...L. lectin i;e CAL possessed complex-sugar ...The lectin was basic in nature (pI ...this lectin; however, pronase-treated versions of both ...
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<p>Functional Relevancies of Trans-Differentiation in the Juxtaglomerular Apparatus of Rat Kidney</p>
... Angiotensin II attenuates the TGF β induced trans-differ- entiation via the angiotensin II AT1 receptors. 36,37 Any physiological or pathophysiological pathway makes the changes in the salt and water balance like ...
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