Calcium-dependent potassium channels
In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root
... of potassium ion currents have been described in rat myometrium: a fast transient current and two calcium-dependent noninactivating currents ...conductance calcium-dependent ...
7
Resveratrol attenuates cortical neuron activity: roles of large conductance calcium-activated potassium channels and voltage-gated sodium channels
... neurotoxicity [16, 42, 49, 54] and also protects against pentylenetetrazole-induced seizures [31, 40]. Furthermore, resveratrol has the ability to inhibit the electrical activity of neurons [26, 30, 50], enabling this ...
9
Stimulation of hERG1 channel activity promotes a calcium- dependent degradation of cyclin E2, but not cyclin E1, in breast cancer cells
... Potassium channels such as the hERG1 protein, that shows enhanced expression in several cancers of different origins and/or stages may represent therapeutic targets if, manipulation of activity of such ...
9
Two pore channels and NAADP dependent calcium signalling
... approximately 1 x 10 6 cells was retrieved from a liquid nitrogen storage facility and rapidly thawed for approximately 2 minutes by partial submersion in a water bath set at 37 ° C. Once thawed, the cell suspension was ...
303
Genetic aspects of primary hyperaldosteronism
... TASK channels, Kir 3.4 channels and the sodium- potassium pump ...voltage dependent L and T-type calcium channels ...allowing calcium influx into the cell. Calcium ...
10
Regulation of vascular ATP-sensitive potassium channels by calcium and inflammatory mediators
... Ca^"^- dependent and -Independent Isoforms exist, although how specificity of action Is achieved Is not completely ...Ca^* channels, K^ channels and phosphollpases (Andrea and Walsh, ...
281
Modulation of pulmonary vasomotor tone in the fetus and neonate
... decades, calcium-dependent (K Ca ), ATP- dependent (K ATP ), and several voltage-dependent (K V ) potassium channels have been identified on both pulmonary endothelial and ...
6
COMPARISON OF ACUTE AND CHRONIC EFFECTS OF NIFEDIPINE ON NALOXONE-PRECIPITATED MORPHINE WITHDRAWAL IN MICE
... of calcium channels in various ac tions of ...ing calcium channels, as well as activating potassium channels, and these effects are thought to contribute to their central ...
8
ATP-dependent potassium channels are implicated in simvastatin pretreatment-induced inhibition of apoptotic cell death after renal ischemia/reperfusion injury
... associated with the membrane depolari- zation and influx of Ca2+ ions and de- crease mitochondrial membrane poten- tial (14). Coalescence of Ca2+ ions in the cytosol triggers apoptotic cell death. This is potentially ...
10
Ion channels expression and function are strongly modified in solid tumors and vascular malformations
... cation channels, calcium Channels voltage-dependent, cation channels sperm associated, FXYD domain containing ion transport regulators, gamma-aminobutyric acid (GABA) receptors, ...
15
The pharmacology of calcium and ATP-dependent potassium channels in erythrocytes and in smooth skeletal muscle
... buffered calcium solution sealed into red cell ...Mg^% calcium caused half-maximal activation at ...pM potassium efflux was ...to calcium was somewhat ...
215
Action Potentials in Rhodnius Oocytes: Repolarization is Sensitive to Potassium Channel Blockers
... These increases in overshoot and duration of APs in barium salines suggest that barium might not only permeate through calcium channels, but might also block a voltage-dependent potassiu[r] ...
14
ATP-sensitive Potassium Channels and L-type Calcium Channels are Involved in Morphine-induced Hyperalgesia after Nociceptive Sensitization in Mice
... channel blockers induce analgesia in laboratory animals (Horvath, Brodacz & Holzer-Petsche, 2001; Miranda et al., 1992). However, in the present study nimodipine by itself did not induce either algesic or analgesic ...
8
Scanning mutagenesis of the I-II loop of the Cav2.2 calcium channel identifies residues Arginine 376 and Valine 416 as molecular determinants of voltage dependent G protein inhibition
... were identified as functionally important binding sites for the Gbg heterodimer [27,30]. To test the contribu- tion of individual residues of these sections to Gbg- mediated channel inhibition, alanine/cysteine scanning ...
7
Membrane potential oscillations in molluscan “burster” neurones
... Both are carried by potassium ions but one depends on an increase in intracellular calcium during the pulse, while the other appears to be simply dependent on the voltage across the cell[r] ...
20
The Effect of Electrolytes on the Muscle of the Fore Gut of Dytiscus Marginalis, With Special Reference to the Action of Potassium
... In all the potassium-calcium mixtures in which a rhythm could be maintained the potassium concentration was so high that, had sodium and calcium been present in the concentrations of the[r] ...
11
Ion Channels in Peripheral Blood Mononuclear Cells – Effect of Culture and Ascorbic Acid.
... on potassium currents, patch clamp experiments were done in PBMC s cultured in the ascorbic acid for 48 hrs and in control cells cultured without ascorbic ...patch. Potassium currents were recorded in ...
126
Regularities and Causality; Generalizations and Causal Explanations
... ion channels and other neuronal structures as if they were Ohmic conductors in order to measure their potentials, currents, resistance, and conductance, Voltmeters and other equipment used to measure electrical ...
43
Short Review of Sulphites as Food Additives
... Sulphites or sulphiting agents refer to sodium hydrogen sulphite, sodium metabisulphite, potassium metabisulphite, calcium sulphite, calcium hydrogen sulphite, and potassium hydrogen sulphite. ...
8
Pharmacological and biophysical characteristics of voltage-dependent calcium channels in rat cerebellar granule neurones
... Species differences between am clones and differences in expression systems together with the coexpression of different accessory subunits from one study to another have complicated the interpretation of data from ...
229