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Calcium release from the ER

Structural aspects of calcium-release activated calcium channel function

Structural aspects of calcium-release activated calcium channel function

... disrupting ER-PM targeting of STIM1 molecules which is dependent on the polybasic stretches of ...in ER stored Ca 2+ , 31,55 signaling the cytosolic domains to induce CRAC entry and maintain basal ...

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Calcium release channel RyR2 regulates insulin release and glucose homeostasis

Calcium release channel RyR2 regulates insulin release and glucose homeostasis

... 2+ release channel on the endoplasmic reticulum (ER) of several types of cells, including cardiomyocytes and pancreatic β ...2+ release is critical for excitation-contraction coupling; however, a ...

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Intracellular calcium release modulates polycystin-2 trafficking

Intracellular calcium release modulates polycystin-2 trafficking

... Our results indicate that CaMK is an important regulator of PC2 trafficking to the PM. Indeed, phos- phorylation has previously been demonstrated in PC2 trafficking [13]. Two evolutionarily conserved phosphor- ylation ...

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Calcium-induced calcium release (CICR) from the

Calcium-induced calcium release (CICR) from the

... The main observations are that (1) measurements of Na + /Ca 2+ exchange current in the presence of caffeine (ie, under conditions that allow measurement of SR release) reveal a slowing [r] ...

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Calcium Release from the Skeletons of Rachitic Puppies

Calcium Release from the Skeletons of Rachitic Puppies

... in calcium and vitamin ...both calcium and vitamin D, while another experimental group was fed a diet deficient in calcium but with adequate vitamin ...serum calcium response fell after ...

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Calcium signaling at ER membrane contact sites

Calcium signaling at ER membrane contact sites

... at ER – mitochondria MCSs, as discussed, is well established but MAMs have more recently been implicated in phospho- lipid transfer (reviewed in [29,61]), with transfer of phosphatidylserine (PS) from the ...

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Abstract We simulate elementary calcium release events (sparks) in a single calcium release unit in

Abstract We simulate elementary calcium release events (sparks) in a single calcium release unit in

... on calcium dependent electronic stochastic transitions, thus “domino-like” CICR process occurs during the first period of Ca 2+ spark ...2+ release at t=10 ms was sufficient to decrease Ca jSR below the ...

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Controlling Bovine Serum Albumin Release From Biomimetic Calcium Phosphate Coatings

Controlling Bovine Serum Albumin Release From Biomimetic Calcium Phosphate Coatings

... BSA Release Behavior in Vitro from Biomimetic Coatings Prepared with Different BSA Adding Time To study the effect of BSA adding time on BSA release behavior, the biomimetic apatite coated titanium ...

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Influence of Sodium and Parathyroid Hormone on Calcium Release from Intestinal Mucosal Cells

Influence of Sodium and Parathyroid Hormone on Calcium Release from Intestinal Mucosal Cells

... and release of 45 Ca from the intestinal mucosal epithelium were investigated under a variety of ...a calcium pool with a half-time of saturation of less than 2 ...- from the ...

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HPM Method Applied to Solve the Model of Calcium Stimulated, Calcium Release Mechanism

HPM Method Applied to Solve the Model of Calcium Stimulated, Calcium Release Mechanism

... , from its initial value to its asymptotic value given by stable critical points by means of analytical expressions provided in this ...the calcium stimulated, calcium released ...

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The Effect of Calcium and Other Salts upon the Release of Glucagon Like Immunoreactivity from the Gut

The Effect of Calcium and Other Salts upon the Release of Glucagon Like Immunoreactivity from the Gut

... J Clin Invest. 1972;51(4):831-836. https://doi.org/10.1172/JCI106878. It has been suggested that glucagon-like immunoreactivity (GLI) of gastrointestinal tissues might, like pancreatic glucagon, have ...

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Involvement of mitochondrial swelling in cytochrome c release from mitochondria treated with calcium and Alloxan

Involvement of mitochondrial swelling in cytochrome c release from mitochondria treated with calcium and Alloxan

... K + +CsA Cyt c Mitochondria were incubated in a medium at a concentration of 1 mg protein/ml. The incubation medium consisted of 0.25 M sucrose, 0.1 M rotenone, 5 mM succinate, 0.1 mM EGTA, and 10 mM Tris-HCl (pH 7.4). ...

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Abnormality in calcium release from skeletal sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia

Abnormality in calcium release from skeletal sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia

... isolated from gracilis muscle of control and malignant hyperthermia (MH)-susceptible ...the calcium-releasing effects of caffeine on isolated SR ...caffeine-induced calcium released from SR is ...

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Calcium entry via TRPV1 but not ASICs induces neuropeptide release from sensory neurons

Calcium entry via TRPV1 but not ASICs induces neuropeptide release from sensory neurons

... 11 Calcium entry via TRPV1, but not ASICs induces CGRP secretion We show that acidification induces CGRP secretion that largely depends on the presence of extracellular Ca 2+ , indicating that Ca 2+ -independent ...

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Calcium Ion Permeation through the Calcium Release Channel (Ryanodine Receptor) of Cardiac Muscle

Calcium Ion Permeation through the Calcium Release Channel (Ryanodine Receptor) of Cardiac Muscle

... The fits to the corresponding IV relations in the mixtures of NaCl and CsCl with CaCl 2 are similar to the fits in the KCl solutions (not shown). Figure 2 compares experimental data in two mixtures of KCl and CaCl 2 with ...

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In vitro gentamicin release from commercially available calcium phosphate bone substitutes influence of carrier type on duration of the release profile

In vitro gentamicin release from commercially available calcium phosphate bone substitutes influence of carrier type on duration of the release profile

... total release was smaller in cements than in granules, possibly indicating that the cement mixing procedure gives a more homogeneous drug-distribution than drug-adsorption onto the irregular porous granules- ...

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Permeation through the Calcium Release Channel of Cardiac Muscle

Permeation through the Calcium Release Channel of Cardiac Muscle

... differs from its bulk value (for this reason the scale of the horizontal axis is different inside the channel 0 < x < 10Å and outside the channel in the baths, x < 0 & x > ...

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Formulation and evaluation of atorvastatin calcium sustained release tablets

Formulation and evaluation of atorvastatin calcium sustained release tablets

... drug release from solid dosage form may be modified by the technologies, which in general are based on modifying drug dissolution through the use of barrier coatings and controlling drug diffusion rates ...

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Inositol Trisphosphate Induces Calcium Release from Nonmitochondrial Stores in Sea Urchin Egg Homogenates"

Inositol Trisphosphate Induces Calcium Release from Nonmitochondrial Stores in Sea Urchin Egg Homogenates"

... Ca" Transport and IP3-induced Rebase in Egg Homogenates Since the previous experiments with intact eggs provide only indirect evidence for IPB-induced Ca2+ release in [r] ...

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Nitrogen, phosphorus, potassium, calcium and magnesium release from two compressed fertilizers: column experiments

Nitrogen, phosphorus, potassium, calcium and magnesium release from two compressed fertilizers: column experiments

... elements. Under the conditions of this study, Ca 2+ and Mg 2+ were usually released at lower rates, especially in the treat- ment 8–8–16 (less than 60 %), while more than 99 % of N was released from both tablets. ...

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