cAMP-activated protein kinase
Original Article Association detection between genetic variants in the microRNA binding sites of toll-like receptors signaling pathway genes and bladder cancer susceptibility
... TLRs signaling pathway genes polymorphisms and bladder cancer risk mitogen-activated protein kinase 1 protein kinase C, beta 1 protein kinase C, alpha protein kinase, cAMP-dependent, reg[r] ...
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Counteracting Regulation of Chromatin Remodeling at a Fission Yeast cAMP Responsive Element-Related Recombination Hotspot by Stress-Activated Protein Kinase, cAMP-Dependent Kinase and Meiosis Regulators
... CRE-binding protein (CREB) family (Takeda et ...Pat1 kinase (Li and Ohta, ...Pat1 kinase by Mei3 then results in M26 chromatin remodeling as well as M26 hotspot acti- activation of Mei2, a key ...
12
Flavonoids in modulation of cell survival signalling pathways
... N-terminal kinase (JNK), and p38, MAPKs (Johnson and Lapadat ...the cAMP response element-binding protein (CREB) (Arany et ...anti-apoptotic protein Bcl-2, and non- transcriptional inhibition ...
9
Non-esterified fatty acids in the ovary: friends or foes?
... monophosphate-activated protein kinase; ATF4: Activating transcription factor 4; cAMP: Cyclic adenosine monophosphate; CCND2: Cyclin D2; CLA: Conjugated linoleic acid; COC: Cumulus oocyte ...
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Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors
... of cAMP, activation of Protein kinase A (PKA) and phosphorylation of the cAMP-response element binding protein (CREB), which, in turn, suppresses the transcription of numerous ...
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Phosphoproteomic Characterization Of Glycogen Synthase Kinase-3
... ribonucleoproteins (snRNPs) and a number of associated proteins (Maniatis and Tasic, 2002). Splicing is catalyzed by a series of sequential steps that bring the 5’ and 3’ ends of splice sites together to from an intron ...
124
The MK2/HuR signaling pathway regulates TNF-α-induced ICAM-1 expression by promoting the stabilization of ICAM-1 mRNA
... It was reported that activation of p38 MAPK via IL-1β and TNF-α is implicated in HuR-mediated stabilization of mRNAs coding for key inflammatory mediators in- cluding IL-6, cyclooxygenase-2 (COX-2) and TNF-α [24]. MK2 ...
11
Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5)
... mitogen-activated protein kinase-activated protein kinase 5 ...MK5 protein is a highly conserved protein kinase within vertebrates sharing 87 to 99% amino ...
21
PubMedCentral-PMC5198172.pdf
... a kinase network ...p21- activated kinases; PKD, protein kinase D; GRK, G-protein coupled receptor kinase; DMPK, dystrophia myotonica-protein kinase; CK, casein ...
15
Supplementing L-isoleucine increases medium protein and alters the expression of genes and proteins involved in milk protein synthesis and energy metabolism in bovine mammary cells
... milk protein synthesis, using an immortalized bovine mammary epithelial (MAC-T) cell ...for protein synthesis for each amino acid was determined by measuring the cell, medium and total protein at 0, ...
14
PKM2, function and expression and regulation
... signal-regulated kinase 2 (ERK2) and bind to the Iso429/Leu431 region of PKM2, mediate Ser37 site phosphorylation on PKM2, and recruit PIN1 to form PRKM2/PIN1 complex, if the Ser37 site is mutated to other amino ...
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Oligopeptide transporter PepT1 in Atlantic cod (Gadus morhua L ): cloning, tissue expression and comparative aspects
... specificity, protein sorting to the membrane, ...and protein domains that are relevant to the general function of the transporter or, conversely, to the determination of a species-specific ...
14
Relationship of the cAMP-dependent protein kinase pathway to the SNF1 protein kinase and invertase expression in Saccharomyces cerevisiae.
... Suppression of the R a f phenotype is not due to restoration of invertase expression: T h e snfl and snf4 mutants are defective i n growth on raffinose at least i n [r] ...
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cAMP/PKA/CREB/GLT1 signaling involved in the antidepressant-like effects of phosphodiesterase 4D inhibitor (GEBR-7b) in rats
... final protein concentration of 1 mg/mL, and then centrifuged at 13,000 × g for 30 minutes at 4 ° ...The cAMP levels from the samples were determined by ELISAassay (Assay Designs, Ann Arbor, MI, ...The ...
9
Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487
... AMP-activated protein kinase (AMPK) is a heterotrimeric Ser/Thr kinase consisting of catalytic (α) and regulatory (β and γ) subunits that acts as a key sensor of cellular and whole-body energy ...
17
Empagliflozin Attenuates Hyperuricemia by Upregulation of ABCG2 via AMPK/AKT/CREB Signaling Pathway in Type 2 Diabetic Mice
... Figure 5. Effects of empagliflozin on uric acid transporters and AMPK/Akt/CREB signaling in cultured HK-2 cells. (A-B) Protein levels and analysis of ABCG2 were assessed by western blot. Levels of ABCG2 were ...
14
Kinase Activity Profiling of Gram-Negative Pneumonia
... approach. Kinase activity arrays enable the analysis of 1,024 con- sensus sequences of protein kinase ...a kinase activity array on whole lung lysates, cellular kinase activities were ...
7
Mitogen-Activated Protein Kinase-Activated Kinase RSK2 Plays a Role in Innate Immune Responses to Influenza Virus Infection
... either protein (data not ...PB2 protein possesses glutamic acid at position 627 (PB2-627E), which supports efficient replication in avian cells but not in mammalian cells at ...RSK2 protein selected ...
8
From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis
... 7.2.3.3 TLRs 1 and 2 Toll-like receptor 2 (TLR2), through the formation of heterodimers with TLRs 1 and 6, has the potential to bind to a range of PAMPs [66]. Poly- morphisms of TLR2 have been associated with increased ...
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Molecular responses to abiotic stress and the development of drought tolerance in plants
... A gene encoding a mitogenactivated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, c[r] ...
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