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Cancer Biology

Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapy

Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapy

... of cancer stem cell ...in cancer biology and the underlying molecular mechanisms of Lgr5-mediated tumor-promoting/suppressive activities, as well as potentially useful preventive strategies in ...

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Testicular teratomas: an intersection of pluripotency, differentiation and cancer biology

Testicular teratomas: an intersection of pluripotency, differentiation and cancer biology

... and cancer biology, and the study of these unusual tumors may hold clues about how natural populations of stem cells are regulated and how their differentiation is ...

11

The progression of HMGB1-induced autophagy in cancer biology

The progression of HMGB1-induced autophagy in cancer biology

... in cancer biology, such as proliferation, migration and che- ...combat cancer from different perspectives, especially in terms of its drug ...

13

How clinical imaging can assess cancer biology

How clinical imaging can assess cancer biology

... of cancer biology together with developments in diagnostic technologies, and expansion of therapeutic options have all contributed to the concept of personalized cancer care with accurate and ...

35

Cancer biology of reading textbook

Cancer biology of reading textbook

... Cancer is a disease that begins when a single cell escapes from the regulation of its own division. Cell division is the process a cell undergoes in order to make copies of itself. This division is normally ...

5

Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology

Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology

... the cancer associated fibroblasts (CAFs), and how these cells are key players in orchestrating the tumor microenvironment composition and tissue microarchitecture, hence also driving tumorigenesis and affecting ...

12

Ecology meets cancer biology: The cancer swamp promotes the lethal cancer phenotype

Ecology meets cancer biology: The cancer swamp promotes the lethal cancer phenotype

... advanced cancer patients, individualized antibody therapy using therapeutics already in use such as anti-inflammatory agents for arthritis, psoriasis, and asthma, could be used to specifically neutralize a ...

10

Circadian Rhythm Disruption in Cancer Biology

Circadian Rhythm Disruption in Cancer Biology

... protecting DNA integrity from exogenous and/or endogenous stimuli (73,74). Sev- eral components of these pathways seem to be entrained by circadian oscillations. Nucleotide excision repair is a DNA re- pair mechanism ...

12

Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2

Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2

... in cancer due to gain-of- function mutations, down-regulation of its suppressors, amplification of gene expression or increase of protein abundance by oncogenic pathways such as PI3K-AKT and MEK-ERK, ...

17

Role of arginine and its methylated derivatives in cancer biology and treatment

Role of arginine and its methylated derivatives in cancer biology and treatment

... 14. Ogilvie GK, Fettman MJ, Mallinckrodt CH, Walton JA, Hansen RA, Davenport DJ, Gross KL, Richardson KL, Rogers Q, Hand MS: Effect of fish oil, arginine, and doxorubicin chemotherapy on remis- sion and survival time for ...

5

DNA Repair in Prostate Cancer: Biology and Clinical Implications.

DNA Repair in Prostate Cancer: Biology and Clinical Implications.

... prostate cancer (PC) have improved over the last decade, castration-resistant PC (CRPC) remains a lethal disease ...other cancer types [2,3], there may be an opportunity to potentially improve patient care ...

9

Cancer Genomics and Biology 2015 – Meeting Report

Cancer Genomics and Biology 2015 – Meeting Report

... Professor Rakesh Kumar from the George Washington University started his plenary lecture by elaborating on the significance of extra- and intra-cellular milieu in modifying the genome through chromatin remodeling and ...

6

Is systems biology a promising approach to resolve controversies in cancer research?

Is systems biology a promising approach to resolve controversies in cancer research?

... context, cancer research should benefit from rejoining the long and successful tradition in the exact sciences and in the biology of yore of dis- carding premises and falsifying ...yes, cancer ...

5

Biology-driven cancer drug development: back to the future

Biology-driven cancer drug development: back to the future

... modern biology and of course this is extremely important in defining the neoplastic ...of cancer cells and tumors ­ a limitless replicative potential, resistance to apop tosis, insensitivity to anti­growth ...

12

The microenvironment in breast cancer progression: biology and implications for treatment

The microenvironment in breast cancer progression: biology and implications for treatment

... requires cancer cells to escape from the primary tumor, survive in the circulation, seed at distant sites and ...the cancer cell to be seeded. For the cancer cells to invade into the blood ...

11

Stress and breast cancer: from epidemiology to molecular biology

Stress and breast cancer: from epidemiology to molecular biology

... Th e animal studies discussed above for the most part demonstrate a connection between stress exposure and breast tumor incidence and growth, corroborating the fi ndings of a subset of the epidemiologic literature. Th is ...

15

The biology and treatment of oligometastatic cancer

The biology and treatment of oligometastatic cancer

... of cancer metastasis ...(aggressive cancer clones to multiple ...aggressive cancer clones to few ...the cancer cells (quality of the diaspora migrants), the quality of the original tumor site ...

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A Review on the Biology of Cancer Stem Cells

A Review on the Biology of Cancer Stem Cells

... the cancer cells capable of differentiation and self-renewal which is the role of CSCs chemotherapy ...that cancer begins from stem ...that cancer does not simply appear ...

8

Mechanical and Systems Biology of Cancer.

Mechanical and Systems Biology of Cancer.

... tumors, cancer cells are embedded in a dense fibrillar ...and cancer cells, cancer-related parameters can be tuned in generalizable models to explore disease ...in cancer progression and ...

18

The biology and role of CD44 in cancer progression: therapeutic implications

The biology and role of CD44 in cancer progression: therapeutic implications

... pancreatic cancer cell population (CFPAC1- CD44 Low cells) that expressed low levels of CD44s but with expression of multiple CD44 variant isoforms also expressed higher levels of ...different cancer stages ...

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