Cancer Immunology
Small molecules as theranostic agents in cancer immunology
... With further research into the molecular mechanisms and roles linking immune suppression and restraint of (pre)malignancies, immunotherapies have revolutionized clinical strategies in the treatment of cancer. ...
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The role of regulatory T cells in cancer immunology
... of cancer patients can be viewed as one of multiple attempts by the tumor to promote its own escape from the host immune system by silencing antitumor immune effector ...
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Evolutionary paradigm in cancer immunology*
... During past years, many mathematical models have been developed describing important aspects of non linear interaction of cancer and human immune system. The idea to use the qualitative theory of dynamical systems ...
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Two Surface-Exposed Elements of the B30.2/SPRY Domain as Potency Determinants of N-Tropic Murine Leukemia Virus Restriction by Human TRIM5α
... Perron,1 Matthew Stremlau,1 and Joseph Sodroski1,2* Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Department of Pathology, Division of AIDS, Harvard Medical Sch[r] ...
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Adaptation of a CCR5-Using, Primary Human Immunodeficiency Virus Type 1 Isolate for CD4-Independent Replication
... MOONEY,1 HYERYUN CHOE,3 AND JOSEPH SODROSKI1,2* Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Department of Pathology,1 and Perlmutter Laboratory, Children’s Ho[r] ...
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Characterization of Simian-Human Immunodeficiency Virus Envelope Glycoprotein Epitopes Recognized by Neutralizing Antibodies from Infected Monkeys
... LETVIN,2 1,3 AND JOSEPH SODROSKI * Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute,1 and Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center,2 Har[r] ...
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Review of the 25th annual scientific meeting of the International Society for Biological Therapy of Cancer
... of Cancer (iSBTc, recently renamed the Society for Immunotherapy of Cancer, SITC) provided a scientific platform for ~500 attendees to exchange cutting-edge information on basic, clinical, and translational ...
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Forensic Immunology
... In order to be able to make positively the diagnosis of human origin of unknown material, the controls as outlined above are needed, viz: Normal rabbit serum: this is used to test if the[r] ...
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Contraindications to immunotherapy: a global approach
... effect cancer; low dose (1 and 3 μg/mL) of recombinant Der p 2 can enhance in vitro cell motil- ity and invasiveness of non-small cell lung cancer cells, promoting metastatic ability of carcinoma cells ...
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The immunology of neurodegeneration
... Increased plaque load and neurodegeneration Increased plaque load and neurodegeneration More rapid disease progression Increased Aβ levels, decreased survival Increased plaque load and m[r] ...
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Defining the critical hurdles in cancer immunotherapy
... of Cancer (SITC), convened an “Immunotherapy Summit” with representatives from immunotherapy organizations representing Europe, Japan, China and North America to discuss collaborations to improve development and ...
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Comparison of the Concentration of Salivary IL-8 in Patients with Oral Squamous Cell Carcinoma and Healthy Subjects
... 10.Su KJ, Lin CW, Chen MK, Yang SF.YU YL.Effects of EZH2 promoter polymorphisms and methylation status on oral squamous cell carcinoma susceptibility and pathology.Am J Cancer Res 2015;5(11):3475-84. 11.Murphy PM, ...
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Cancer: The Great Challenge for Immunology
... human cancer anti gens have made an astounding, although largely ig nored, contribution to our understanding of the pathogenesis of ...a cancer-specific antigen has not been isolated for any human ...for ...
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CLINICAL AND VACCINE IMMUNOLOGY (formerly Clinical and Diagnostic Laboratory Immunology)
... Once all the material intended for publication has been determined to be adequate, the manuscript is scheduled for the next available issue and an acceptance letter indicating the month [r] ...
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Critical view of anaphylaxis epidemiology: open questions and new perspectives
... AAAAI: American Academy of Allergy Asthma and Immunology; ACAAI: American College of Allergy Asthma and Immunology; ASCIA: Australian Soci‑ ety of Clinical Immunology and Allergy; EAACI[r] ...
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The Latency-Associated Nuclear Antigen Encoded by Kaposi's Sarcoma-Associated Herpesvirus Activates Two Major Essential Epstein-Barr Virus Latent Promoters
... ROBERTSON* Medical Scientist Training Program, Cell and Molecular Biology Graduate Program, Department of Microbiology and Immunology, and Comprehensive Cancer and Geriatrics Center, Uni[r] ...
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Tumorigenic Potential of a Recombinant Retrovirus Containing Sequences from Moloney Murine Leukemia Virus and Feline Leukemia Virus
... LEVY1* Department of Microbiology and Immunology and Tulane Cancer Center, Tulane Medical School, New Orleans, Louisiana 70112,1 and Department of Molecular Biology and Biochemistry and [r] ...
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Analysis of the cytolytic T-lymphocyte response to herpes simplex virus type 1 glycoprotein B during primary and secondary infection.
... JENNINGS1 2,3* Department of Microbiology and Immunology, 1 Center of Excellence for Arthritis and Rheumatology, 4 and Center for Excellence in Cancer Research and Education,2 Louisiana [r] ...
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Comparative analysis of immune checkpoint molecules and their potential role in the transmissible Tasmanian Devil facial tumor disease
... FIGURE 1 | Generalized schematic of checkpoint molecule structure and expression, and the balance between stimulatory and inhibitory signaling. (A) The net balance of inhibitory ( − , blue) and stimulatory ( + , red) ...
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Mutations which affect the inhibition of protein phosphatase 2A by simian virus 40 small-t antigen in vitro decrease viral transformation.
... MUMBY,2 AND KATHLEEN RUNDELL'* Department of Microbiology-Immunology and The Cancer Center, Northwestern University, Chicago, Illinois 60611-3008,l and Department of Pharmacology, Univer[r] ...
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