Cap-independent translation element
Structure and function of a novel cap independent translation element in the 3' untranslated region of a viral RNA
... Because the mRNAs of BYDV gRNA, sgRNAl and sgRNA2 all contain the same 3'terminal sequence, they use a common translation element that allows expression of their mRNAs equivalent to that[r] ...
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trans Regulation of Cap-Independent Translation by a Viral Subgenomic RNA
... allow translation of 5 ⴕ -distal open reading ...cellular translation machinery. Translation of the uncapped Barley yellow dwarf virus genomic RNA (gRNA) and subgenomic RNA1 (sgRNA1) is driven by the ...
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Cap-Independent Translational Enhancement of Turnip Crinkle Virus Genomic and Subgenomic RNAs
... of translation have been reported. The enhancement of the translation of specific viral mRNAs leading to high levels of protein synthesis of specific genes in plants may well be a fundamental mechanism by ...
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A Small Yeast RNA Blocks Hepatitis C Virus Internal Ribosome Entry Site (HCV IRES)-Mediated Translation and Inhibits Replication of a Chimeric Poliovirus under Translational Control of the HCV IRES Element
... IRES-mediated translation both in vivo and in ...IRES-mediated cap-independent translation was markedly inhibited in cells constitutively expressing IRNA compared to control hepatoma ...
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The 3′ Untranslated Region of Pea Enation Mosaic Virus Contains Two T-Shaped, Ribosome-Binding, Cap-Independent Translation Enhancers
... cis-acting element known as an internal ribosome entry site (IRES), which is located in the 5= untranslated region (5=UTR) and may overlap the initiation codon and extend into the trans- lated open reading frame ...
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A single nucleotide substitution in the internal ribosome entry site of foot-and-mouth disease virus leads to enhanced cap-independent translation in vivo.
... Ribavirin cures cells of a persistent Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest DISCUSSION In this report, we have shown that a point mutation in the IRES element [r] ...
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THE WARBURG EFFECT: A POSSIBLE ROLE OF CAP INDEPENDENT TRANSLATION Ajaz Ahmad Waza*, Shabir Ahmad Bhat, Sajad AliDOWNLOAD/VIEW
... protein translation in normal and stress conditions. A) Cap dependent translation: Eukaryotic initiation factor binds to the 5’- cap on the mRNA, followed by recruitment of 40S subunit to the ...
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Cap-Independent Translation Mechanism of Red Clover Necrotic Mosaic Virus RNA2 Differs from That of RNA1 and Is Linked to RNA Replication
... no cap structure at the 5 ⴕ end and no poly(A) tail at the 3 ⴕ ...RNA element (3 ⴕ TE-DR1), which is required for cap-independent ...a cap-independent translational mechanism of ...
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The 5′ Untranslated Region of the Human T-Cell Lymphotropic Virus Type 1 mRNA Enables Cap-Independent Translation Initiation
... RNA element does not contain an IRES, it does suggest that transfection of a DNA bicistronic reporter cannot be used exclusively to establish IRES activity (or ...vitro translation assays ...monocistronic ...
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Core Protein-Coding Sequence, but Not Core Protein, Modulates the Efficiency of Cap-Independent Translation Directed by the Internal Ribosome Entry Site of Hepatitis C Virus
... rected translation in ...cient cap-independent translation of reporter proteins (43) or for the replication of a chimeric poliovirus in which the HCV IRES replaced the picornavirus ...
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A Primary Determinant of Cap-Independent Translation Is Located in the 3′-Proximal Region of the Tomato Bushy Stunt Virus Genome
... Our initial trans-expression assay used DI-82 and DI-83 for expression of p33. An undesirable feature of these mRNAs is that they are both replicable, a property which could influence the abundance of the messages and/or ...
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Ribosome Binding to a 5′ Translational Enhancer Is Altered in the Presence of the 3′ Untranslated Region in Cap-Independent Translation of Turnip Crinkle Virus
... during cap-dependent translation (24, 29), allowing for protection of terminal regions of the RNA, recruitment of eIFs, and recycling of ribosomal ...enhance translation by bringing CITE-bound ...
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A Viral Noncoding RNA Generated by cis-Element-Mediated Protection against 5′→3′ RNA Decay Represses both Cap-Independent and Cap-Dependent Translation
... both cap-independent and cap-poly(A)-de- pendent translation in vitro and in ...both cap-independent translation (14, 27) and neg- ative-strand RNA synthesis ...of ...
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CUNI System for the WMT17 Multimodal Translation Task
... The challenge of the WMT Multimodal Transla- tion Task is to exploit cross-lingual information in automatic image caption generation. The state- of-the-art models in both machine translation and automatic image ...
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Sapovirus Translation Requires an Interaction between VPg and the Cap Binding Protein eIF4E
... The VPg-containing plasmid was expressed in the B834(DE3) Esche- richia coli strain. Large-scale recombinant protein production was per- formed in autoinducible ZYP medium (1% N-Z-Amine, 0.5% yeast ex- tract, and salts) ...
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Taking aim at translation for tumor therapy
... Increased cap-dependent mRNA translation rates are frequently observed in human ...the cap binding protein eukaryotic translation initiation factor 4E (eIF4E), leading to enhanced ...
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In Vivo and In Vitro Identification of Structural and Sequence Elements of the Human Parechovirus 5′ Untranslated Region Required for Internal Initiation
... for translation initiation in cardio/aphthoviruses (13, 25, ...between translation and RNA replication (16), the structural domains defined here seem to represent the irreducible minimum for IRES ...in ...
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Translational Control Mediates Lifespan Extension Due to Dietary Restriction in Drosophila
... for translation of most mRNAs (Sonenberg, Hershey et ...most translation initiation begins with the interaction of the cap-binding complex (eIF4F) with the mRNA “cap” structure, m 7 GpppN ...
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A Phylogenetically Conserved Stem-Loop Structure at the 5′ Border of the Internal Ribosome Entry Site of Hepatitis C Virus Is Required for Cap-Independent Viral Translation
... initiates translation of its polyprotein under the control of an internal ribosome entry site (IRES) that comprises most of the 341-nucleotide (nt) 5 * nontranslated RNA (5 * ...
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Chinese translation and validation of the Sport Concussion Assessment Tool 3 (SCAT3)
... In this stage, a bilingual native Chinese-speaking univer- sity graduate of English language studies was made responsible for back-translating the first common trans- lation from Chinese to English. The translator had no ...
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