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cartilage/bone interface

Bioactive Scaffolds for Regeneration of Cartilage and Subchondral Bone Interface

Bioactive Scaffolds for Regeneration of Cartilage and Subchondral Bone Interface

... complex interface microstructure between them. The osteochondral interface is described by the interaction of calcified cartilage and the underlying subchondral ...osteochondral interface ...

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Dynamic viscoelastic characterisation of human osteochondral tissue: understanding the effect of the cartilage bone interface

Dynamic viscoelastic characterisation of human osteochondral tissue: understanding the effect of the cartilage bone interface

... of cartilage that has maintained health throughout its ...and cartilage viscoelasti- city was not established in the present study, despite being demonstrated in bovine tissue ...the cartilage ...

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Copper-incorporated bioactive glass-ceramics inducing anti-inflammatory phenotype and regeneration of cartilage/bone interface

Copper-incorporated bioactive glass-ceramics inducing anti-inflammatory phenotype and regeneration of cartilage/bone interface

... of cartilage via activating the immune response in ...of cartilage and subchondral bone tissues, indicating its promising application in preventing the development of ...

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Bone Mineral “Quality”: Differing Characteristics of Calcified Microsphere Populations at the Osteoporotic and Osteoarthritic Femoral Articulation Front

Bone Mineral “Quality”: Differing Characteristics of Calcified Microsphere Populations at the Osteoporotic and Osteoarthritic Femoral Articulation Front

... the cartilage/bone interface region by immersion in hydrazine hydrate to expose the anorganic mineral topography for microscopy and FEGSEM ...chondral bone a proportion of the filamentous ...

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Original Article Experimental study of biologically active icariin combined with a porous PLGA/TCP scaffold to repair cartilage and subchondral bone in articular cartilage defect in rabbits

Original Article Experimental study of biologically active icariin combined with a porous PLGA/TCP scaffold to repair cartilage and subchondral bone in articular cartilage defect in rabbits

... articular cartilage defect in ...articular cartilage defect animal model with a 5 mm diameter by 4 mm depth defect in the femoral intercondylar ...subchondral bone was in better shape in the ...

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Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA

Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA

... articular cartilage and the subchondral bone plate, it has been hypothesized that antiresorptive drugs can also reduce cartilage degradation, inhibit excessive turnover of the subchondral bone ...

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Randomized controlled studies on the efficacy of antiarthritic agents in inhibiting cartilage degeneration and pain associated with progression of osteoarthritis in the rat

Randomized controlled studies on the efficacy of antiarthritic agents in inhibiting cartilage degeneration and pain associated with progression of osteoarthritis in the rat

... MMP-13 activity as well as RANKL-mediated osteoclas- togenesis and at a range of concentrations (Figs. 1, 2 and 3, Table 2, and Additional file 1: Figs. S3–S18). The drug IMMD-0354 (Institute for Medicinal Molecular ...

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Tibial subchondral bone size and knee cartilage defects: relevance to knee osteoarthritis

Tibial subchondral bone size and knee cartilage defects: relevance to knee osteoarthritis

... Knee cartilage defects can also be visualized directly from ...of cartilage defects is graded on a 5-point scale similar to that used for ar throscopy as shown in Table 1 ...the cartilage surface can ...

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Assessment of Cartilage Strip and Bone Cement in Ossiculoplasty

Assessment of Cartilage Strip and Bone Cement in Ossiculoplasty

... (HAP) bone cement has been developed as an alternative to ionomeric cement, as the safety of HAP in middle ear surgery has been demonstrated for a long time (1) ...

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Pericellular collagen I coating for enhanced homing and chondrogenic differentiation of mesenchymal stem cells in direct intra-articular injection

Pericellular collagen I coating for enhanced homing and chondrogenic differentiation of mesenchymal stem cells in direct intra-articular injection

... on cartilage slices, enhancing MSC homing and retention to cartilage ...DIAI, cartilage defects have been repaired by MSCs to varying ...of cartilage regeneration judging from macroscopic ...

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High resolution MRI imaging at 9 4 Tesla of the osteochondral unit in a translational model of articular cartilage repair

High resolution MRI imaging at 9 4 Tesla of the osteochondral unit in a translational model of articular cartilage repair

... articular cartilage, repair tissue, subchondral bone plate and subarticular spongiosa within the osteochondral ...different cartilage repair ...articular cartilage defects have a history of ...

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Molecular changes in articular cartilage and subchondral bone in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis

Molecular changes in articular cartilage and subchondral bone in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis

... articular cartilage in similar experimental models of OA ...the cartilage layer, without integrating infor- mation from the pre-articular subchondral bone in response to the surgically-induced joint ...

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Articular cartilage mineralization in osteoarthritis of the hip

Articular cartilage mineralization in osteoarthritis of the hip

... After cartilage specimens were analyzed by DCR, electron microscope analysis was performed on a subset of the first 20 consecutive tangential-cut cartilage specimens out of the total ...

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Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice

Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice

... inflammation, cartilage damage, pannus formation, and bone resorp- ...pannus, bone resorption, and cartilage damage seen in all takinib-treated ...

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Effect of celastrol on bone structure and mechanics in arthritic rats

Effect of celastrol on bone structure and mechanics in arthritic rats

... Objective Rheumatoid arthritis (RA) is characterised by chronic inflammation leading to articular bone and cartilage damage. Despite recent progress in RA management, adverse effects, lack of efficacy and ...

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Cartilage specific RBPjκ dependent and  independent Notch signals regulate cartilage and bone development

Cartilage specific RBPjκ dependent and independent Notch signals regulate cartilage and bone development

... early cartilage progenitor cells of the chick limb using a Dll1 replication-competent retrovirus, the maturation and hypertrophic differentiation program of chondrocytes was inhibited (Crowe et ...6. ...

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Original Article An investigation over the impact of conventional Chinese bone setting to cartilage and the VEGF expression in cartilage cells in rats with knee osteoarthritis disease

Original Article An investigation over the impact of conventional Chinese bone setting to cartilage and the VEGF expression in cartilage cells in rats with knee osteoarthritis disease

... Chinese bone setting, named Xiao Yu San Plaster has been used for treating knee osteo- arthritis for hundreds of years and achieved dramatic ...this bone setting on cartilage tissue ...this ...

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New developments in osteoarthritis  Sex differences in magnetic resonance imaging based biomarkers and in those of joint metabolism

New developments in osteoarthritis Sex differences in magnetic resonance imaging based biomarkers and in those of joint metabolism

... Cartilage oligomeric matrix protein (COMP) is a 64-kDa pentameric matrix protein found in most joint tissues, including cartilage, bone, tendon, ligament, synovium, and vascular smooth muscle. It is ...

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Usefulness of using laser induced photoacoustic measurement and 3 0 Tesla MRI to assess knee cartilage damage: a comparison study

Usefulness of using laser induced photoacoustic measurement and 3 0 Tesla MRI to assess knee cartilage damage: a comparison study

... joint cartilage with trypsin and per- formed DT imaging, and they reported that the trypsin treatment group had a more elevated ADC than before treatment ...articular cartilage also was treated with trypsin ...

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Building the backbone: the development and evolution of vertebral patterning

Building the backbone: the development and evolution of vertebral patterning

... of bone that forms around and eventually replaces the cartilage template (Peignoux-Deville et ...calcified cartilage and arch bone is important, as it allows for comparison with ...the ...

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