cartilage injury
Up regulated expression of E2F2 is necessary for p16INK4a induced cartilage injury
... It has been proved that p16INK4a was able to inhibit cell cycle by targeting CDK4/6, and therefore maintain- ing the activity of retinoblastoma (pRb) that could con- trol cell fate decision of chondrocytes [42–44]. E2F ...
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Original Article Notch pathway and matrix metalloproteinases in the repair of cartilage injury with bone marrow mesenchymal stem cells
... of cartilage injury with bone marrow mesenchymal stem cells (BMMSCs), aiming to explore the interaction among Notch path- way, MMP-1 and MMP-13 in the cartilage matrix ...of cartilage ...
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Original Article Effect of sheep tail fat on the knee joint cartilage injury induced in rats with formalin
... the cartilage injury induced in the rat knee joint with forma- lin: STFF group (n=6) was administered STF 500 mg/kg and GCMHBF group (n=6) GCMHB mixture of 500 mg/kg doses with ...
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Transplantation of a Scaffold Free Cartilage Tissue Analogue for the Treatment of Physeal Cartilage Injury of the Proximal Tibia in Rabbits
... hyaline cartilage have distinct genetic properties differ- ent from those of the growth plate ...plate cartilage comprise more compati- ble genetic properties for the treatment of growth plate ...hyaline ...
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Does Low intensity pulsed ultrasound treatment repair articular cartilage injury? A rabbit model study
... protect cartilage by inhibiting matrix metalloproteinase-13 (MMP-13) mRNA expres- sion, and stimulate chondrocyte proliferation and matrix production in chondrocytes ...articular cartilage metabolism has ...
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Autologous cell derived, tissue engineered cartilage for repairing articular cartilage lesions in the knee: study protocol for a randomized controlled trial
... of cartilage dam- age and harvesting of cartilage seed cells): the scope, lo- cation, and size of articular cartilage injury will be assessed with preoperative ...niscus injury will be ...
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Synoviocytes protect cartilage from the effects of injury in vitro
... and cartilage are limited, intercellular interactions have been identified where synovial cells and chondrocytes communicate by direct contact [16] or indirectly by synovial cell release of mo- lecular agents ...
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“D-003, A MIXTURE OF SUGARCANE WAX ACIDS, REDUCES JOINT DAMAGE IN MONOSODIUM IODOACETATE-INDUCED OSTEOARTHRITIS IN RATS” by Sarahi Mendoza Castaño, Miriam Noa Puig, Maikel Valle Clara, Nilda Mendoza Hernández, Rosa Mas Ferreiro, Cuba. Digital copy link
... of cartilage and produce adverse side effects that may limit their ...and cartilage damage, cellular abnormalities, matrix staining, extent of inflammation, pannus formation and presence of ...of ...
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<p>Cordycepin Alleviates Anterior Cruciate Ligament Transection (ACLT)-Induced Knee Osteoarthritis Through Regulating TGF-β Activity and Autophagy</p>
... Methods: Sprague Dawley rats were induced by anterior cruciate ligament transection (ACLT) to establish knee osteoarthritis model. To investigate the role of COR in knee osteoarthritis, rats were injected with 5, 10, and ...
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Different responses to mechanical injury in neonatal and adult ovine articular cartilage
... to cartilage injury in neonatal and adult sheep by microarray analysis of gene ...injured cartilage relative to normal ...injured cartilage relative to normal ...normal cartilage ...
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Osmolarity influences chondrocyte repair after injury in human articular cartilage
... injured cartilage to predict the responses of sharply wounded ar- ticular cartilage during articular surgery ...of cartilage and preventing cartilage degen- eration ...thickness ...
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Original Article Correlation between signal changes on MRI sequences and cartilage histopathologic variation after cartilage impact injury in the knee joint: an animal study
... joint injury is the most fre- quently-occurred articular injury in ...articular cartilage, result- ing in traumatic ...the cartilage injury, accu- rate judgement of the severity of ...
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Molecular changes indicative of cartilage degeneration and osteoarthritis development in patients with anterior cruciate ligament injury
... knee injury affecting mainly young and active population ...post injury [2, ...of injury, time from the onset of injury, obesity, joint malignment, concomitant presence of an acute meniscal or ...
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Usefulness of using laser induced photoacoustic measurement and 3 0 Tesla MRI to assess knee cartilage damage: a comparison study
... the cartilage, with its value reportedly being increased by damage to the cartil- age matrix and especially by a decrease in collagen or an increase in water content ...assessing cartilage damage [4, ...
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Early cartilage abnormalities at the hip are associated with obesity and body composition measures – a 3 0T MRI community based study
... The mechanisms by which an increased BMI and fat mass adversely affects hip cartilage is unknown. It is possible that deleterious structural changes may in part be due to excessive loading of the hip joint caused ...
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Biomarkers in Osteoarthritis
... in cartilage homeostasis [286], characterised by overactive catabolic activity and reduced anabolic activity in cartilage matrix ...and cartilage oligometric matrix protein (COMP) [288], have shown ...
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Association of adiposity measures in childhood and adulthood with knee cartilage thickness, volume and bone area in young adults
... knee cartilage surfaces ...the cartilage surface areas, quantitative parameters of cartilage and bone morphology were derived, including cartilage thickness, cartilage volume and ...
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Preoperative considerations, operative preparation, and postoperative care for rib cartilage use in rhinoplasty
... Seventh rib cartilage has been known as the safest anatomically. It is situated over the abdominal cavity and thus can lessen the chance of pneumothorax since the parietal pleura of the lung runs down to reach the ...
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MMP13 is a critical target gene during the progression of osteoarthritis
... notably cartilage loss down to and even below the tidemark in saline control mice, was decelerated with 1, 5, or 10 mg/kg of CL82198 injection, particularly with the 10 mg/kg dose (Figure ...3C). Cartilage ...
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Degradation of cartilage proteoglycan by human leukocyte granule neutral proteases a model of joint injury II Degradation of isolated bovine nasal cartilage proteoglycan
... Extracts of human peripheral blood polymorphonuclear leukocyte granules, and two purified proteases derived from such extracts, an elastase and a chymotrypsin-like enzyme, degrade isolated bovine nasal cartilage ...
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