CCAAT-enhancer-binding proteins
CCAAT/enhancer binding proteins in normal mammary development and breast cancer
... CCAAT/enhancer binding proteins (C/EBPs) are a family of leucine zipper, transcription factors that bind to DNA as homodimers and heterodimers. They regulate cellular proliferation, ...
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Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats
... transfer proteins; CEBP β , CCAAT-enhancer binding proteins; CON, control; CPT-1A, Carnitine palmitoyltransferase 1A; CYP27A1, sterol 27-hydroxylase; FABP1, fatty acid binding ...
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Anti adipogenic effects of the traditional herbal formula Dohongsamul tang in 3T3 L1 adipocytes
... : CCAAT/enhancer binding proteins alpha; CCK-8: Cell counting kit-8; DEX: Dexamethasone; DHSMT: Dohongsamul- Tang; DMEM: Dulbeco ’ s modified eagle ’ s medium; DMSO: Dimethyl sulfoxide; DPBS: ...
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Contaminating reactivity of a monoclonal CCAAT/Enhancer Binding Protein β antibody in differentiating myoblasts
... Objective: CCAAT/Enhancer Binding proteins (C/EBPs) are transcription factors involved in the regulation of a variety of cellular processes. We used the Abcam Recombinant Anti‑C/EBP beta ...
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Endoplasmic reticulum stress and apoptosis
... luminal binding protein; C/EBP – CCAAT/enhancer- binding proteins; eIF-2α – eukaryotic translation initiation factor; EOR – ER overloaded response; ER – endoplasmic reticulum; GADD 153 ...
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Molecular structure and transcriptional regulation of the gene for the platelet derived growth factor alpha receptor in cultured vascular smooth muscle cells
... nuclear proteins from VSMC through the binding site for CCAAT/enhancer-binding proteins, and members of the C/enhancer-binding protein family play a significant ...
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A Protein Encoded by the Bovine Herpesvirus 1 Latency-Related Gene Interacts with Specific Cellular Regulatory Proteins, Including CCAAT Enhancer Binding Protein Alpha
... bound proteins electrophoresed by 12% ...lysate. Proteins were transferred to a PVDF membrane and probed with anti-C/EBP- ␣ antibody that was diluted ...contain proteins bound to the Ni ⫹ ...bound ...
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CEBPD amplification and overexpression in urothelial carcinoma: a driver of tumor metastasis indicating adverse prognosis
... the CCAAT/enhancer-binding protein family. These proteins function as transcription factors and modulate many biological processes including cell differentiation, motility, growth arrest, ...
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CCAAT/enhancer binding protein β is required for satellite cell self-renewal
... cell population, marked by loss of MyoD expression. In addition to downregulation of MyoD expression, it is known that the SC population itself is heterogeneous and can undergo both asymmetrical and symmetrical divisions ...
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Myostatin gene promoter: structure, conservation and importance as a target for muscle modulation
... : CCAAT/enhancer-binding protein- α ; ChoRE: Carbohydrate responsive element; ChREBP: Carbohydrate responsive element binding protein; CIK: Grass carp kidney cells; COMP1: Cooperates with ...
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Biological roles of CCAAT/Enhancer-binding protein delta during inflammation
... Activation of CEBPD has been observed in several acute inflammation diseases. However, the detailed mechanisms and regulations involving CEBPD need to be studied extensively. The acute-phase response (APR) protein takes ...
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Oligonucleotides targeting coagulation factor mRNAs: use in thrombosis and hemophilia research and therapy
... key proteins are produced in the liver, and thereby siRNAs and ASOs can also be used as appropriate tools to target these proteins in ...these proteins in physiology and ...
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Next-Generation Sequence Analysis of the Genome of RFHVMn, the Macaque Homolog of Kaposi's Sarcoma (KS)-Associated Herpesvirus, from a KS-Like Tumor of a Pig-Tailed Macaque
... four CCAAT/enhancer binding protein (C/ EBP) motifs that have been identified in the KSHV Ori-L and Ori-R regions as critical for binding the ORF K8/bZIP homolog of KSHV and lytic DNA ...
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The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice
... hepatic triglyceride in ob/ob ; Shp −/− mice, mRNA from livers of control- and troglitazone-treated mice was an- alyzed (Figure 3B). mRNA levels of fatty acid translo- case (CD36), fatty acid synthase (FAS), adipocyte ...
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The Many Faces of C/EBPδ and their Relevance for Inflammation and Cancer
... Proteins whose aberrant activity can drive tumor development are termed oncogenes. Proteins whose normal activity primarily inhibits tumor development have been termed tumor suppressors. However, since the ...
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Low-dose monobutyl phthalate stimulates steroidogenesis through steroidogenic acute regulatory protein regulated by SF-1, GATA-4 and C/EBP-beta in mouse Leydig tumor cells
... Results: In this study, various doses of MBP (0, 10( − 9), 10( − 8), 10( − 7), or 10( − 6) M) were added to the medium followed by stimulation of MLTC-1 cells with human chorionic gonadotrophin (hCG). The results showed ...
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The role of stromal cancer-associated fibroblasts in pancreatic cancer
... The heterogeneity demonstrated within CAF popula- tions necessitates reliable markers. Some have been established, but a true, unique marker is yet to be discovered. Native fibroblasts stain for vimentin and, once ...
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A novel BCR-ABL1 fusion gene with genetic heterogeneity indicates a good prognosis in a chronic myeloid leukemia case
... AML: Acute myeloid leukemia; C/EBP α : CCAAT enhancer binding protein α ; CML: Chronic myelogenous leukemia; CMML: Chronic myelomonocytic leukemia; CNL: Chronic neutrophilic leukemia; FI[r] ...
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Genomic effects of the vitamin D receptor: Potentially the link between vitamin D, immune cells, and multiple sclerosis
... C/EBP, CCAAT/enhancer-binding protein; ChIA-PET, chromatin interaction analysis by paired-end tag sequencing; ChIP- seq, chromatin immunoprecipitation sequencing; CIS, clinically isolated syn- drome; ...
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TSG-6 secreted by human adipose tissue-derived mesenchymal stem cells ameliorates severe acute pancreatitis via ER stress downregulation in mice
... CHOP: CCAAT-enhancer-binding protein homologous protein; DMEM: Dulbecco ’ s modified Eagle ’ s medium; ELISA: Enzyme-linked immunosorbent assay; ER: Endoplasmic reticulum; FBS: Foetal bovine serum; ...
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