Cell death and survival
Gene trapping identifies transiently induced survival genes during programmed cell death
... the identity of the trapped known genes, the strategy seems highly specific for regulatory genes induced during pro- grammed cell death. Accordingly, the majority of genes upregulated by IL-3 withdrawal ...
10
Reduction of Cardiac Cell Death after Helium Postconditioning in Rats: Transcriptional Analysis of Cell Death and Survival Pathways
... which cell death/survival pathways are ...the cell protective ef- fects of helium postconditioning by PCR array analysis of genes involved in necrosis, apoptosis and ...of cell ...
11
Theranostic Imaging of the Kinases and Proteases that Modulate Cell Death and Survival
... exacerbates cell death in the heart during is- chemia ...in cell death/survival and the need for novel imaging tools to better understand how to modulate these ...
8
GSK-3β-mediated regulation of cadmium-induced cell death and survival
... When cells were pretreated for 30 min with the Ca 2+ chelator BAPTA-AM (10 μ M) before treatment with 25 μ M Cd, the Cd-induced upregulation of Akt and GSK-3 β phosphorylation was found to have significantly decreased ...
10
Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival.
... apoptotic cell death response following DISC formation to the activation of NF- k B and cell survival (Figure 7), both beneficial features for tumor ...to death-ligand-induced apoptosis ...
14
The Role of Autophagy in Cell Survival and Cell Death
... temporary survival mechanism, under stressful conditions is well recognized (Mizushima, ...in cell death (Baehrecke, ...sustain survival upon severe stress and/or ...of cell ...
9
Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia
... induce death in lymphoid cells through the glucocorticoid receptor (GR) and p53 ...ALL cell death and the contribution of the bone marrow microenvironment to drug response/resistance remain ...and ...
21
Cytoplasmic vacuolization in cell death and survival
... Ras-induced methuosis is accompanied by activation of caspases; however, their suppression has no effect on cell survival [31]. Methuosis process does not depend on the activity of kinase PI3K class I, ...
27
Systematic analysis of NLMP suggests nuclear localization of RTK/MET kinases resemble cancer cell clearance
... of death signaling but also elevated Bcl-2 for ...of cell cycle, ...cancer cell death and ...both cell sur- vival and cell death in cancerous ...and cell lines. ...
12
Zinc in innate and adaptive tumor immunity
... normal cell survival (as above) and for cell death via its role in ...of survival due to its early sensitivity to cell ...on cell death and survival, where ...
16
Obligatory participation of macrophages in an angiopoietin 2 mediated cell death switch
... including cell-survival through the PI3-kinase-Akt signaling pathway (Datta et ...with survival signal ...endothelial cell growth factor (VEGF), is an important angiogenic stimulus ...
10
Mesenchymal stem/stromal cell function in modulating cell death
... as cell therapy to individuals with degenerative and/or inflammatory disorders can help improve organ features and resolve inflammation, as demonstrated in preclinical studies and to some extent in clinical ...’ ...
12
CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin
... Programmed cell death that are often governed by similar molecular mechanisms ...and survival pathways regulated by CK2 include WNT/β-catenin, Erk, and AKT signaling ...evading cell Programmed ...
13
Characterisation of ERK distribution and activity in rat pheochromocytoma cells : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Biology at Massey University
... Nerve growth factor NGF binds to the NGF receptor, TrkA, at the tips of nerve cell axons, sending a signal that prevents programmed cell death and causes survival, growth, and differenti[r] ...
9
Computational Modelling of HT Carcinoma Cells using different Averaging Tree Techniques
... for cell survival/ death by using Random forest and boosting tree and random forest methods which are different Averaging tree ...in cell survival/ ...to cell death while ...
9
ATF6 Signaling Is Required for Efficient West Nile Virus Replication by Promoting Cell Survival and Inhibition of Innate Immune Responses
... T he endoplasmic reticulum (ER) is a multifunctional signaling organelle, controlling protein and lipid synthesis, calcium ho- meostasis, and components of redox signaling (1). Accumulation of misfolded or unfolded ...
9
The C1 Domain in Cancer Signaling Molecules: Regulation by Lipids and Protein-Protein Interactions
... induced cell death/survival and also suggested that inhibition of PKCε may be a useful therapeutic approach to radiosensitize prostate cancer ...
161
Delayed Inflammatory and Cell Death Responses Are Associated with Reduced Pathogenicity in Lujo Virus-Infected Cynomolgus Macaques
... and survival. Notably, the delay of cell death-related path- ways may contribute to improved survival of distinct populations of immune cells, which in turn can alter pathogenesis in the ...
10
Understanding the role of PD-L1/PD1 pathway blockade and autophagy in cancer therapy
... tumor cell survival and decreases the effectiveness of chemo- therapy by enhancing cancer cell metabolism and inhibiting its cell death pathway, there have been suggestions about using ...
5
Hoffmann, Ruth (2010): Investigation of helenalin-induced cell death in Bcl-2 overexpressing Jurkat cells. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... against cell death but it also can cause cellular ...to cell death, or, autophagy can occur upstream of apoptosis whereas it also simultaneously modulates independent means of cell ...
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