cell renewal
Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis
... T cell renewal in CSF following AHSCT ...T cell repertoire in CSF before therapy was undetectable at months 24 or 48 after AHSCT therapy (Figure 2A), we wanted to determine the proportion of new T ...
13
Perturbation of cell renewal in the haemopoetic tissues of drug treated and leukaemic mice
... K urland, K incade and M oore (1977) u sin g a tw o -la y e r cu ltu re sy ste m which p reven ted m a cro p h a g e-ly m p h o cy te contact and p erm itted B -cell activ a tion . A dherent p erito n ea l m a cro ...
284
CELL PROLIFERATION KINETICS IN THE GASTROINTESTINAL TRACT OF MAN I CELL RENEWAL IN COLON AND RECTUM
... The following measurements were made: 1 position of labeled epithelial cells in the colonic and rectal crypts, 2 counts of labeled and unlabeled mitoses at various intervals after labeli[r] ...
11
RASSF1C modulates the expression of a stem cell renewal gene, PIWIL1
... Total RNA from human lung cancer cell lines was iso- lated from confluent cultures using the Absolutely RNA Microprep Kit (Stratagene, La Jolla, CA). 1 μg of total RNA was used in reverse transcriptase (RT) ...
10
DNA methylation in stem cell renewal and multipotency
... stem cell? Is it possible to revert the diff erentiation program by manipu lating the epigenome? How safe is this reversion? Th e recent discovery that nearly one quarter of all methylation identifi ed in ES cells ...
9
Cell lineage branching as a strategy for proliferative control
... stem cell acts as the precursor of both the committed progenitors of neurons and sustentacular (glial) cells ...stem cell to in- hibit neuronal, and favor glial, ...stem cell numbers rise in activin ...
15
STUDIES OF THE ANEMIA AND IRON METABOLISM IN CANCER
... The T4 and the serum iron concentration are two of the chief parameters in the calculation of red cell renewal rates, and errors in the estimation of either may be responsible for the di[r] ...
16
Erythropoietin promotes breast tumorigenesis through tumor initiating cell self renewal
... cancer cell lines, and primary tumors have also been shown to produce EPO (6, 7, ...cancer cell lines (Figure 6, B and C), but not human mammary epithelial cells ...
12
The NOTCH1-HEY1 pathway regulates self-renewal and epithelial-mesenchymal transition of salivary adenoid cystic carcinoma cells
... stem cell-like cells (CSCs) in colorectal cancer ...stem cell characteristics in GBM cells ...tumor cell spheroids were significantly ...stem cell-like cell (CSC) marker in human cancer ...
13
Stem Cell Research: A Novel Boulevard towards Improved Bovine Mastitis Management
... Endothelial progenitor cells are a population of rare cells that circulate in the blood with the ability to differentiate into endothelial cells which make the lining of blood vessels and are capable of generating new ...
12
Impact of the SCF signaling pathway on leukemia stem cell- mediated ATL initiation and progression in an HBZ transgenic mouse model
... The global gene expression study results indicate that many HBZ-interacting genes, such as the AP-1 family genes including c-Jun, Junb [40], and Jund [41], which are associated with leukemogenesis, are highly upregulated ...
17
A Renewal Authority?
... commercial zones, as well as for homes in residential zones, can provide economically and on a pedestrian scale in many cases local, social amenities and cultural and recreational faci[r] ...
8
Disrupted in schizophrenia 1 (DISC1) inhibits glioblastoma development by regulating mitochondria dynamics
... Figure 5: Targeting DISC1 by shRNA decreases glioblastoma stem-like cells self-renewal and alters the mitochondrial dynamic. (A) The morphology of tumor spheres formed by the cancer stem cells from ...
12
Hypoxia promotes satellite cell self renewal and enhances the efficiency of myoblast transplantation
... signaling is known to activate Hes1, which then inhibits MyoD expression (Kopan et al., 1994). Hirai et al. reported that MyoD regulates miR-1 expression through directly binding to the upstream enhancer (Hirai et al., ...
9
The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells
... chromatin conformations, which make it possible to switch to any type of cells [68]. Epigenetic modification plays an important role in the proliferation and differen- tiation of ESCs, while the miR-290-295 cluster is ...
10
Drosophila small ovary gene is required for transposon silencing and heterochromatin organization, and ensures germline stem cell maintenance and differentiation
... Self-renewal and differentiation of stem cells is one of the fundamental biological phenomena relying on proper chromatin organization. In our study, we describe a novel chromatin regulator encoded by the ...
13
Clinical potentials of human pluripotent stem cells in lung diseases
... Pulmonary diseases are one leading cause of morbidity and mortality worldwide. Currently available treatments can only alleviate symptoms or delay disease progression within a limited time range for patients with ...
8
Epstein-Barr Virus Latent Membrane Protein 1 Induces Cancer Stem/Progenitor-Like Cells in Nasopharyngeal Epithelial Cell Lines
... Epstein-Barr virus (EBV) is a human herpesvirus that is associated with several malignancies, such as Burkitt lym- phoma (BL), Hodgkin lymphoma (HL), gastric cancer, and, most importantly, nasopharyngeal carcinoma (NPC) ...
10
CCAAT/enhancer binding protein β is required for satellite cell self-renewal
... self- renewal can be rescued in C/EBPβ-deficient myoblasts by overexpression of the Notch intracellular domain (NICD) indicating that C/EBPβ acts, at least in part, by regulating Notch ...
11
Integrin Rac signalling for mammary epithelial stem cell self renewal
... bipotent cell main- tenance and self-renewal, though both Rac1 and ILK are dispensable for the maintenance of luminal progenitors that form hollow ...
11